Steady-state availability of sodium channels. Interactions between activation and slow inactivation

A quantitative description of membrane current and its application to conduction and excitation in nerve

1952 • 21,965 citations

Inactivation of the sodium channel. I. Sodium current experiments.

1977 • 1,509 citations

Structural parts involved in activation and inactivation of the sodium channel

1989 • 1,189 citations

Inactivation of the sodium channel. II. Gating current experiments.

1977 • 943 citations

Restoration of Inactivation in Mutants of Shaker Potassium Channels by a Peptide Derived from ShB

1990 • 752 citations

Identification of an Intracellular Peptide Segment Involved in Sodium Channel Inactivation

1988 • 382 citations

Slow inactivation of the sodium conductance in squid giant axons. Pronase resistance.

1978 • 263 citations

A neutral amino acid change in segment IIS4 dramatically alters the gating properties of the voltage-dependent sodium channel.

1990 • 186 citations

Distribution and kinetics of membrane dielectric polarization. 1. Long-term inactivation of gating currents.

1982 • 183 citations

Evidence for two types of sodium conductance in axons perfused with sodium fluoride solution

1970 • 166 citations

Fast and slow gating of sodium channels encoded by a single mRNA

1990 • 162 citations

The Effects of External Potassium and Long Duration Voltage Conditioning on the Amplitude of Sodium Currents in the Giant Axon of the Squid, Loligo pealei

1969 • 158 citations

Gating of Na channels. Inactivation modifiers discriminate among models.

1987 • 150 citations

Identification of an intracellular peptide segment involved in sodium channel inactivation

1988 • 135 citations

Sodium channel activation in the squid giant axon. Steady state properties.

1985 • 114 citations

Ionic Conductance Changes in Voltage Clamped Crayfish Axons at Low pH

1974 • 103 citations

Sodium and potassium currents in squid axons perfused with fluoride solutions

1970 • 102 citations

Solute inaccessible aqueous volume changes during opening of the potassium channel of the squid giant axon

1990 • 98 citations

Intramembrane charge movement in frog skeletal muscle fibres. Properties of charge 2.

1987 • 96 citations

Distribution and kinetics of membrane dielectric polarization. II. Frequency domain studies of gating currents.

1982 • 84 citations

Rate constants associated with changes in sodium conductance in axons perfused with sodium fluoride

1970 • 75 citations

Comparison between slow sodium channel inactivation in rat slow‐ and fast‐twitch muscle.

1987 • 74 citations

Slow sodium channel inactivation in rat fast‐twitch muscle.

1987 • 68 citations

Slow sodium inactivation in Myxicola axons. Evidence for a second inactive state

1976 • 62 citations

Slow mechanism for sodium permeability inactivation in myelinated nerve fibre of Xenopus laevis.

1977 • 60 citations

Burst kinetics of sodium channels which lack fast inactivation in mouse neuroblastoma cells.

1987 • 58 citations

Modification of slow sodium inactivation in nerve after internal perfusion with trypsin

1978 • 52 citations

Interactions of monovalent cations with sodium channels in squid axon. I. Modification of physiological inactivation gating.

1985 • 48 citations

Saxitoxin and tetrodotoxin. Electrostatic effects on sodium channel gating current in crayfish axons

1986 • 38 citations

Slow recovery of sodium current and 'gating current' from inactivation.

1977 • 31 citations

The steady-state distribution of gating charge in crayfish giant axons

1989 • 22 citations

Holding potential affects the apparent voltage-sensitivity of sodium channel activation in crayfish giant axons

1990 • 21 citations

On the voltage dependence of inactivation in the sodium channel of the squid giant axon

1991 • 20 citations

Gating current "fractionation" in crayfish giant axons

1991 • 16 citations

Osmotic and pharmacological effects of formamide on capacity current, gating current, and sodium current in crayfish giant axons

1989 • 14 citations

Gating current kinetics in Myxicola giant axons. Order of the back transition rate constants

1991 • 10 citations