The release of tumor necrosis factor from endotoxin-stimulated rat Kupffer cells is regulated by prostaglandin E2 and dexamethasone

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

Shock and Tissue Injury Induced by Recombinant Human Cachectin

1986 • 2,587 citations

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

1984 • 1,738 citations

Cachectin and tumour necrosis factor as two sides of the same biological coin

1986 • 1,659 citations

Control of Cachectin (Tumor Necrosis Factor) Synthesis: Mechanisms of Endotoxin Resistance

1986 • 1,305 citations

Human tumor necrosis factor. Production, purification, and characterization.

1985 • 922 citations

Cells of the hepatic sinusoid

1989 • 589 citations

Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression.

1986 • 585 citations

Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamine-treated mice.

1987 • 560 citations

Steroids in the Treatment of Clinical Septic Shock

1976 • 540 citations

The spread of tumors in the human body

1935 • 487 citations

[58] Rapid extraction of arachidonic acid metabolites from biological samples using octadecylsilyl silica

1982 • 423 citations

Macrophages as a source of tumoricidal activity (tumor-necrotizing factor)

1980 • 398 citations

Acute-Phase Reactants

1974 • 398 citations

Tumor necrosis factor type alpha stimulates human endothelial cells to produce granulocyte/macrophage colony-stimulating factor.

1986 • 396 citations

Cell-associated tumor necrosis factor (TNF) as a killing mechanism of activated cytotoxic macrophages.

1987 • 361 citations

Tumor necrosis factor: a potent effector molecule for tumor cell killing by activated macrophages.

1986 • 360 citations

Regulation of macrophage tumor necrosis factor production by prostaglandin E2

1986 • 344 citations

Studies on the anti-tumor efficacy of systemically administered recombinant tumor necrosis factor against several murine tumors in vivo.

1987 • 292 citations

Lipoprotein lipase suppression in 3T3-L1 cells by an endotoxin-induced mediator from exudate cells.

1982 • 272 citations

Centrifugation: A Practical Approach

1985 • 222 citations

The pit cell: Description of a new type of cell occurring in rat liver sinusoids and peripheral blood

1976 • 195 citations

Human Recombinant TNF Suppresses Lipoprotein Lipase Activity and Stimulates Lipolysis in 3T3-L1 Cells1

1987 • 175 citations

Rat hepatic sinusoidal endothelial cells in monolayer culture

1988 • 145 citations

Large granular lymphocytes or “Pit cells” from rat liver: isolation, ultrastructural characterization and natural killer activity

1987 • 141 citations

Eicosanoids, Signal Molecules of Liver Cells

1985 • 139 citations

Production of an anti-tumour cytotoxin by human monocytes.

1981 • 133 citations

Synthesis of prostanoids and cyclic nucleotides by phagocytosing rat Kupffer cells

1984 • 118 citations

Superoxide Release by Zymosan‐Stimulated Rat Kupffer Cells in vitro

1981 • 106 citations

Tumor necrosis factor production by human monocytes is a regulated event: induction of TNF-alpha-mediated cellular cytotoxicity by endotoxin.

1986 • 105 citations

Cachectin/tumor necrosis factor: An endogenous mediator of shock and inflammation

1986 • 103 citations

Macrophage-mediated cytotoxicity: role of a soluble macrophage cytotoxic factor similar to lymphotoxin and tumor necrosis factor.

1983 • 99 citations

Differential inhibition of prostaglandin and superoxide production by dexamethasone in primary cultures of rat Kupffer cells

1986 • 90 citations

Involvement of Prostaglandin E and Adenosine 3′ 5′‐Monophosphate in Lipopolysaccharide‐Stimulated Collagenase Release by Rat Kupffer Cells

1982 • 89 citations

Tumor necrosis factor as effector molecule in monocyte mediated cytotoxicity.

1986 • 89 citations

pH homeostasis : mechanisms and control

1988 • 83 citations

Glucocorticoid regulation of mouse mammary tumor virus gene expression

1979 • 82 citations

Leukotrienes: Biosynthesis, Metabolism, and Analysis

1985 • 63 citations

Role for macrophage products in endotoxin-induced polymorphonuclear leukocyte accumulation during inflammation.

1987 • 61 citations

Induction of acute phase proteins by dexamethasone in rat hepatocyte primary cultures

1984 • 58 citations

Lipopolysaccharide-mediated macrophage activation: the role of calcium in the generation of tumoricidal activity.

1987 • 55 citations

The effect of kupffer cell stimulation or depression on the development of liver metastases in the rat

1986 • 46 citations

Cultured Ito cells of rat liver express the α₂‐macroglobulin gene

1987 • 45 citations

A REGULATORY PATHWAY FOR FIBRINOGEN BIOSYNTHESIS INVOLVING AN INDIRECT FEEDBACK LOOP

1982 • 41 citations

Liver macrophages (Kupffer cells) as cytotoxic effector cells in extracellular and intracellular cytotoxicity

1985 • 41 citations

Calmodulin content and activity of Ca²⁺‐ATPase and phospholipase A² in rat Kupffer cells

1984 • 21 citations

Cortisol dependent acute metabolic responses in rat liver cells

1978 • 20 citations

Lipomodulin: A Modulator of Cellular Phospholipid Metabolism

1984 • 10 citations

Activation of cytotoxic activity in cultures of bone marrow‐derived macrophages by indomethacin

1987 • 6 citations

Interferon-beta-1 - an intermediate in the tnf-alpha induced increased mhc-class-i expression and autocrine regulator of the constitutional mhc-class-i expression

1987 • 3 citations

Extragenomic effects of glucocorticoids.

1982 • 3 citations

Deleted Work

1955 • 0 citations