The HMG-domain protein Ixr1 blocks excision repair of cisplatin-DNA adducts in yeast

HMG domain proteins: architectural elements in the assembly of nucleoprotein structures

1994 • 813 citations

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair.

1994 • 759 citations

Specific Binding of Chromosomal Protein HMG1 to DNA Damaged by the Anticancer Drug Cisplatin

1992 • 492 citations

XPG endonuclease makes the 3′ incision in human DNA nucleotide excision repair

1994 • 481 citations

Analysis of Events Associated With Cell Cycle Arrest at G2 Phase and Cell Death Induced by Cisplatin

1990 • 447 citations

Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer.

1992 • 428 citations

Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair

1993 • 317 citations

Xeroderma pigmentosum complementation group C cells remove pyrimidine dimers selectively from the transcribed strand of active genes.

1991 • 313 citations

Mechanism of cis-diamminedichloroplatinum(II)-induced cytotoxicity: role of G2 arrest and DNA double-strand breaks.

1988 • 307 citations

Specific association between the human DNA repair proteins XPA and ERCC1.

1994 • 304 citations

Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA

1993 • 295 citations

Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair.

1994 • 275 citations

Specific Cleavage of Model Recombination and Repair Intermediates by the Yeast Rad1-Rad10 DNA Endonuclease

1994 • 265 citations

Influence of cis-diamminedichloroplatinum(II) on DNA synthesis and cell cycle progression in excision repair proficient and deficient Chinese hamster ovary cells.

1988 • 226 citations

ISOLATION AND CHARACTERIZATION OF MMS-SENSITIVE MUTANTS OF SACCHAROMYCES CEREVISIAE

1977 • 216 citations

Yeast DNA repair and recombination proteins Rad1 and Rad1O constitute a single-stranded-DNA endonuclease

1993 • 198 citations

RAD9-dependent G1 arrest defines a second checkpoint for damaged DNA in the cell cycle of Saccharomyces cerevisiae.

1993 • 195 citations

Formation of a ternary complex by human XPA, ERCC1, and ERCC4(XPF) excision repair proteins.

1994 • 186 citations

It was a very good year for DNA repair

1994 • 181 citations

Ixr1, a Yeast Protein That Binds to Platinated DNA and Confers Sensitivity to Cisplatin

1993 • 177 citations

Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast

1994 • 163 citations

Mutation of cysteine-88 in the Saccharomyces cerevisiae RAD6 protein abolishes its ubiquitin-conjugating activity and its various biological functions.

1990 • 155 citations

Purification of nuclear proteins that bind to cisplatin-damaged DNA. Identity with high mobility group proteins 1 and 2.

1992 • 150 citations

Cisplatin-DNA adducts are molecular decoys for the ribosomal RNA transcription factor hUBF (human upstream binding factor).

1994 • 149 citations

Yeast excision repair gene RAD2 encodes a single-stranded DNA endonuclease

1993 • 143 citations

Cloning and sequence analysis of the Saccharomyces cerevisiae RAD9 gene and further evidence that its product is required for cell cycle arrest induced by DNA damage.

1989 • 134 citations

Relationships between functionality and genetic toxicology of selected DNA-damaging agents

1984 • 123 citations

YeastRAD14 and human xeroderma pigmentosum group A DNA-repair genes encode homologous proteins

1992 • 120 citations

Repair synthesis by human cell extracts in DNA damaged bycis- andtrans-diamminedichloroplatinum(II)

1989 • 113 citations

Purification and characterization of the Saccharomyces cerevisiae RAD1/RAD10 endonuclease.

1993 • 112 citations

Interaction of Platinum Antitumor Compounds with DNA

1990 • 103 citations

Yeast DNA-repair gene RAD14 encodes a zinc metalloprotein with affinity for ultraviolet-damaged DNA.

1993 • 98 citations

Xeroderma Pigmentosum Complementation Group C Cells Remove Pyrimidine Dimers Selectively from the Transcribed Strand of Active Genes

1991 • 92 citations

Nucleotide-excision repair of DNA in cell-free extracts of the yeast Saccharomyces cerevisiae.

1993 • 87 citations

Cloning of a Subunit of Yeast RNA Oolymerase II Transcription Factor b and CTD Kinase

1992 • 77 citations

Yeast nucleotide excision repair proteins Rad2 and Rad4 interact with RNA polymerase II basal transcription factor b (TFIIH).

1994 • 75 citations

Gene-specific DNA repair in xeroderma pigmentosum complementation groups A, C, D, and F. Relation to cellular survival and clinical features.

1993 • 72 citations

Enhanced repair of a cisplatin‐damaged reporter chloramphenicol‐O‐acetyltransferase gene and altered activities of DNA polymerases α and β, and DNA ligase in cells of a human malignant glioma following in vivo cisplatin therapy

1994 • 55 citations

The ORD1 gene encodes a transcription factor involved in oxygen regulation and is identical to IXR1, a gene that confers cisplatin sensitivity to Saccharomyces cerevisiae.

1994 • 52 citations

Biological processing of DNA modified by platinum compounds

1990 • 51 citations

Saccharomyces cerevisiae RAD2 gene: isolation, subcloning, and partial characterization.

1984 • 51 citations

Formation and stability of interstrand cross-links induced by cis- and trans-diamminedichloroplatinum (II) in the DNA of Saccharomyces cerevisiae strains differing in repair capacity

1989 • 49 citations

Mechanisms of cisplatin (cis-diamminodichloroplatinum II)-induced cytotoxicity and genotoxicity in yeast

1984 • 45 citations

Molecular cloning and characterization of the yeast RAD10 gene and expression of RAD10 protein in E. coli.

1985 • 44 citations

Yeast RAD3 protein binds directly to both SSL2 and SSL1 proteins: implications for the structure and function of transcription/repair factor b.

1994 • 42 citations

Eukaryotic DNA repair: Glimpses through the yeast Saccharomyces cerevisiae

1991 • 41 citations

Yeast genes involved in DNA-repair processes: new looks on old faces

1991 • 40 citations

Deficient gene specific repair of cisplatin-induced lesions in Xeroderma pigmentosum and Fanconi's anemia cell lines

1993 • 40 citations

RAD4 gene of Saccharomyces cerevisiae: molecular cloning and partial characterization of a gene that is inactivated in Escherichia coli.

1987 • 37 citations

Purification of Rad1 Protein from Saccharomyces cerevisiae and Further Characterization of the Rad1/Rad10 Endonuclease Complex

1994 • 31 citations

Influence of DNA repair deficiencies on the UV sensitivity of yeast cells in different cell cycle stages

1990 • 30 citations

Consequences of HMG-Domain Protein Binding to Cisplatin-Modified DNA

1995 • 15 citations

Yeast Nucleotide Excision Repair Proteins Rad2 and Rad4 Interact with RNA Polymerase II Basal Transcription Factor b (TFIIH)

1994 • 11 citations

Flow Cytometric Analyses of the Characteristics of Tumor Cells Treated with Two Platinum Compounds: 1,1‐Cyclobutanedicarboxylato(2‐aminomethylpyrrolidine)‐platinum(II) and Cisplatin

1992 • 9 citations