Eukaryotic DNA repair: Glimpses through the yeast Saccharomyces cerevisiae

The molecular biology of the yeast saccharomyces

1982 • 1,165 citations

DNA REPAIR ENZYMES

1988 • 822 citations

Complementation of the xeroderma pigmentosum DNA repair defect in cell-free extracts

1988 • 448 citations

A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders xeroderma pigmentosum and Cockayne's syndrome

1990 • 440 citations

Nucleotide excision repair in Escherichia coli

1990 • 420 citations

Xeroderma Pigmentosum Group E Cells Lack a Nuclear Factor That Binds to Damaged DNA

1988 • 417 citations

Deoxyribonucleic acid repair in the yeast Saccharomyces cerevisiae

1988 • 361 citations

Molecular characterization of the human excision repair gene : cDNA cloning and amino acid homology with the yeast DNA repair gene

1986 • 330 citations

Recombination-stimulating sequences in yeast ribosomal DNA correspond to sequences regulating transcription by RNA polymerase I

1987 • 317 citations

The isolation, genetics and survival characteristics of ultraviolet light-sensitive mutants in yeast

1968 • 286 citations

ERCC2: cDNA cloning and molecular characterization of a human nucleotide excision repair gene with high homology to yeast RAD3.

1990 • 274 citations

REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymerase

1989 • 270 citations

Mutation of lysine-48 to arginine in the yeast RAD3 protein abolishes its ATPase and DNA helicase activities but not the ability to bind ATP.

1988 • 263 citations

RAD3 protein of Saccharomyces cerevisiae is a DNA helicase.

1987 • 222 citations

RAD1, an excision repair gene of Saccharomyces cerevisiae, is also involved in recombination.

1988 • 209 citations

RADH, a gene ofSaccharomyces cerevisiaeencoding a putative DNA helicase involved in DNA repair. Characteristics of radH mutants and sequence of the gene

1989 • 194 citations

RAD10, an excision repair gene of Saccharomyces cerevisiae, is involved in the RAD1 pathway of mitotic recombination.

1990 • 155 citations

Mechanisms and consequences of DNA damage processing

1987 • 152 citations

Cisplatin-resistant cells express increased levels of a factor that recognizes damaged DNA.

1990 • 143 citations

The yeast RAD50 gene encodes a predicted 153-kD protein containing a purine nucleotide-binding domain and two large heptad-repeat regions.

1989 • 139 citations

The RAD3 gene of Saccharomyces cerevisiae encodes a DNA-dependent ATPase.

1987 • 130 citations

A yeast excision-repair gene is inducible by DNA damaging agents.

1986 • 125 citations

Nucleotide sequence, transcript mapping, and regulation of the RAD2 gene of Saccharomyces cerevisiae

1986 • 97 citations

Phosphodiesterases Involved in DNA Repair

1987 • 95 citations

A constitutive damage-specific DNA-binding protein is synthesized at higher levels in UV-irradiated primate cells.

1990 • 92 citations

The nucleotide sequence of theRAD3gene ofSaccharomyces cerevisiae: a potential adenine nucleotide binding amino acid sequence and a nonessential acidic carboxyl terminal region

1985 • 83 citations

Interactions between Yeast Photolyase and Nucleotide Excision Repair Proteins in Saccharomyces cerevisiae and Escherichia coli

1989 • 81 citations

Expression of the yeast PHR1 gene is induced by DNA-damaging agents.

1990 • 78 citations

Spontaneous mitotic recombination in yeast: the hyper-recombinational rem1 mutations are alleles of the RAD3 gene.

1988 • 77 citations

The cloned human DNA excision repair gene ERCC-1 fails to correct xeroderma pigmentosum complementation groups A through I

1989 • 74 citations

Differential repair of UV damage in rad mutants of Saccharomyces cerevisiae: a possible function of G2 arrest upon UV irradiation.

1990 • 70 citations

Structure and function of the (A) BC excinuclease of Escherichia coli

1990 • 70 citations

An eighth complementation group of rodent cells hypersensitive to ultraviolet radiation

1988 • 65 citations

Transcript levels of theSaccharomyes cerevisiaeDNA repair geneRAD23increase in response to UV light andin meiosis but remain constant in the mitotic cell cycle

1990 • 64 citations

Purification and Characterization of Rad3 ATPase/DNA helicase from Saccharomyces cerevisiae

1989 • 63 citations

Evidence that xeroderma pigmentosum cells from complementation group E are deficient in a homolog of yeast photolyase.

1989 • 62 citations

The UvrABC endonuclease system of Escherichia coli — A view from Baltimore

1990 • 62 citations

Interactions between yeast photolyase and nucleotide excision repair proteins in Saccharomyces cerevisiae and Escherichia coli.

1989 • 59 citations

Regulation of the RAD2 gene of Saccharomyces cervisiae

1989 • 55 citations

大腸菌(A)BCエクシヌクレアーゼの構造と機能

1990 • 49 citations

Genetic and molecular analysis of recombination events in Saccharomyces cerevisiae occurring in the presence of the hyper-recombination mutation hpr1.

1989 • 45 citations

Do we know the cause of xeroderma pigmentosum?

1990 • 44 citations

Use of in vivo and in vitro assays for the characterization of mammalian excision repair and isolation of repair proteins

1990 • 44 citations

Regulated expression of theSaccharomyces cerevisiaeDNA repair gene RAD7 in response to DNA damage and during sporulation

1990 • 43 citations

Effects of multiple yeast rad3 mutant alleles on UV sensitivity, mutability, and mitotic recombination

1990 • 38 citations

Differential repair of UV damage in Saccharomyces cerevisiae is cell cycle dependent.

1990 • 30 citations

A yeast DNA repair gene partially complements defective excision repair in mammalian cells.

1988 • 27 citations