Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-D-aspartate but not by 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionate and kainate in cultured cerebral cortical neurons.

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores

1989 • 1,616 citations

Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay

1987 • 1,280 citations

Quinoxalinediones: Potent Competitive Non-NMDA Glutamate Receptor Antagonists

1988 • 1,202 citations

Glutamate stimulates inositol phosphate formation in striatal neurones

1985 • 734 citations

Rat cortical neurons in cell culture: Culture methods, cell morphology, electrophysiology, and synapse formation

1978 • 482 citations

2-Amino-5-phosphonovalerate (2APV), a potent and selective antagonist of amino acid-induced and synaptic excitation

1981 • 468 citations

Delayed neurotoxicity of excitatory amino acids In vitro

1987 • 332 citations

The temporal integration of the aldosterone secretory response to angiotensin occurs via two intracellular pathways.

1984 • 332 citations

The Calcium Channel Blocker Nifedipine Attenuates Slow Excitatory Amino Acid Neurotoxicity

1990 • 271 citations

Dantrolene

1986 • 252 citations

Calcium, Excitotoxins, and Neuronal Death in the Brain^a

1989 • 235 citations

Dantrolene Prevents Glutamate Cytotoxicity and Ca²⁺ Release from Intracellular Stores in Cultured Cerebral Cortical Neurons

1991 • 232 citations

Excitatory amino acid-induced release of 3H-GABA from cultured mouse cerebral cortex interneurons

1987 • 224 citations

Direct Evidence That Excitotoxicity in Cultured Neurons Is Mediated via N‐Methyl‐D‐Aspartate (NMDA) as well as Non‐NMDA Receptors

1989 • 208 citations

Development of excitatory amino acid induced cytotoxicity in cultured neurons

1990 • 148 citations

Glutamate‐Induced Increase in Intracellular Ca²⁺ in Cerebral Cortex Neurons Is Transient in Immature Cells but Permanent in Mature Cells

1989 • 116 citations

Cultured Neurons as Model Systems for Biochemical and Pharmacological Studies on Receptors for Neurotransmitter Amino Acids

1985 • 102 citations

Glutamate receptor activation in cultured cerebellar granule cells increases cytosolic free Ca2+ by mobilization of cellular Ca2+ and activation of Ca2+ influx

1989 • 72 citations

The calcium channel blocker nifedipine attenuates slow excitatory amino acid neurotoxicity

1990 • 53 citations

Calcium dependency of n-methyl-d-aspartate toxicity in slices from the immature rat hippocampus

1989 • 49 citations

Possible role of cGMP in excitatory amino acid induced cytotoxicity in cultured cerebral cortical neurons

1992 • 40 citations

Novel Glutamate Receptor Antagonists Selectively Protect Against Kainic Acid Neurotoxicity in Cultured Cerebral Cortex Neurons

1990 • 37 citations

Phenobarbital protects cerebral cortex neurones against toxicity induced by kainate but not by other excitatory amino acids

1990 • 33 citations

Glutamate‐Induced ⁴⁵Ca²⁺ Uptake into Immature Cerebral Cortex Neurons Shows a Distinct Pharmacological Profile

1989 • 16 citations

Excitatory amino acid signal transduction in cerebellar cell cultures.

1986 • 15 citations