Antioxidant and triglyceride-lowering effects of vitamin E associated with the prevention of abnormalities in the reactivity and morphology of aorta from streptozotocin-diabetic rats

Role of Oxidative Stress in Development of Complications in Diabetes

1991 • 3,774 citations

Advanced Glycosylation End Products in Tissue and the Biochemical Basis of Diabetic Complications

1988 • 2,527 citations

Estimation of product of lipid peroxidation (malonyl dialdehyde) in biochemical systems

1966 • 2,120 citations

Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method

1979 • 1,477 citations

Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta.

1985 • 1,266 citations

Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes.

1991 • 1,161 citations

Free radicals and diabetes

1988 • 1,127 citations

Role of oxidative stress in development of complications in diabetes

1991 • 787 citations

HYPOFERRÆMIA IN OBESE ADOLESCENTS

1962 • 650 citations

Role of vitamin E in preventing the oxidation of low-density lipoprotein

1991 • 649 citations

Free radicals in diabetic endothelial cell dysfunction

1994 • 398 citations

Diabetes mellitus, hypertension, and cardiovascular disease: Which role for oxidative stress?

1995 • 367 citations

Non-enzymatic glycosylation and the chronic complications of diabetes: an overview

1984 • 312 citations

Impairment of endothelium‐dependent relaxation and changes in levels of cyclic GMP in aorta from streptozotocin‐induced diabetic rats

1989 • 294 citations

Cyclic guanosine monophosphate inhibition of contraction may be mediated through inhibition of phosphatidylinositol hydrolysis in rat aorta.

1986 • 282 citations

Antioxidant treatment of diabetic rats inhibits lipoprotein oxidation and cytotoxicity.

1989 • 265 citations

DISFUNCTION OF VASCULAR ENDOTHELIUM IN DIABETES MELLITUS

1993 • 259 citations

Low-dose alpha-tocopherol improves and high-dose alpha-tocopherol worsens endothelial vasodilator function in cholesterol-fed rabbits.

1994 • 229 citations

Lipoprotein glycation and its metabolic consequences

1997 • 228 citations

Insulin's effect on protein kinase C and diacylglycerol induced by diabetes and glucose in vascular tissues

1994 • 186 citations

Native and oxidized low‐density lipoproteins have different inhibitory effects on endothelium‐derived relaxing factor in the rabbit aorta

1990 • 183 citations

Inhibition of smooth muscle cell proliferation and protein kinase C activity by tocopherols and tocotrienols

1993 • 178 citations

Daily Vitamin E Supplements Improve Metabolic Control But Not Insulin Secretion in Elderly Type II Diabetic Patients

1993 • 176 citations

Normalization of Diacylglycerol-Protein Kinase C Activation by Vitamin E in Aorta of Diabetic Rats and Cultured Rat Smooth Muscle Cells Exposed to Elevated Glucose Levels

1994 • 170 citations

Glucose‐induced metabolic imbalances in the pathogenesis of diabetic vascular disease

1991 • 151 citations

Possible superoxide radical-induced alteration of vascular reactivity in aortas from streptozotocin-treated rats.

1993 • 141 citations

Chronic vitamin E treatment prevents defective endothelium-dependent relaxation in diabetic rat aorta

1995 • 138 citations

Endothelium‐derived relaxing factor alters calcium fluxes in rabbit aorta: a cyclic guanosine monophosphate‐mediated effect.

1986 • 136 citations

Enhanced Contractile Responses of Arteries from Diabetic Rats to α1-Adrenoceptor Stimulation in the Absence and Presence of Extracellular Calcium

1990 • 133 citations

Effects of anti-oxidant treatment on sciatic nerve dysfunction in streptozotocin-diabetic rats; comparison with essential fatty acids

1995 • 111 citations

Elevated lipid peroxidation and vitamin e-quinone levels in heart ventricles of streptozotocin-treated diabetic rats

1995 • 110 citations

Vitamin E protects against impairment of endothelium-mediated relaxations in cholesterol-fed rabbits.

1994 • 99 citations

Vascular contraction induced by activation of membrane calcium ion channels is enhanced in streptozotocin-diabetes.

1990 • 97 citations

Lipoprotein Oxidation and Lipoprotein-lnduced Cell Injury in Diabetes

1992 • 91 citations

EDRF and cyclic GMP control gating of receptor-operated calcium channels in vascular smooth muscle

1986 • 75 citations

Characterization of vascular relaxant factor released from cultured endothelial cells.

1987 • 71 citations

Protective effect of vitamin E on linoleic acid hydroperoxide-induced injury to human endothelial cells

1991 • 54 citations

Normalization of diacylglycerol-protein kinase C activation by vitamin E in aorta of diabetic rats and cultured rat smooth muscle cells exposed to elevated glucose levels

1994 • 49 citations

Triglyceride-lowering Effect of Dietary Vitamin E in Streptozocin-induced Diabetic Rats: Increased Lipoprotein Lipase Activity in Livers of Diabetic Rats Fed High Dietary Vitamin E

1986 • 46 citations

Mechanisms of increased responses of the aorta to .ALPHA.-adrenoceptor agonists in streptozotocin-induced diabetic rats.

1988 • 44 citations

The role of endothelial cells on the alterations in vascular reactivity induced by insulin-dependent diabetes mellitus: Effects of insulin treatment

1993 • 44 citations

Vitamin E restores reduced prostacyclin synthesis in aortic endothelial cells cultured with a high concentration of glucose

1992 • 42 citations

Effects of PP-56 and Vitamin E on Platelet Hyperaggregability, Fatty Acid Abnormalities, and Clinical Manifestations in Streptozocin-Induced Diabetic Rats

1991 • 38 citations

Effect of Vitamin E on Linoleic Acid-Mediated Induction of Peroxisomal Enzymes in Cultured Porcine Endothelial Cells

1990 • 36 citations

Effect of vitamin E on oxysterol- and fatty acid hydroperoxide-induced changes of repair and permeability properties of cultured endothelial cell monolayers.

1988 • 35 citations

Differences in Onset of Impaired Endothelial Responses and in Effects of Vitamin E in the Hypercholesterolemic Rabbit Carotid and Renal Arteries

1995 • 33 citations

Differences in vascular responses to vasoactive agents of basilar artery and aorta from rabbits with alloxan-induced diabetes

1990 • 33 citations

Effect of Cilazapril and Indomethacin on Endothelial Dysfunction in the Aortas of Spontaneously Hypertensive Rats

1993 • 29 citations

High Glucose Reduces Specific Binding for <scp>D</scp>-α-Tocopherol in Cultured Aortic Endothelial Cells

1993 • 27 citations

The effect of vanadyl treatment on vascular responsiveness of streptozotocin-diabetic rats

1994 • 26 citations

Recovery after dietary vitamin E supplementation of impaired endothelial function in vitamin E‐deficient rats

1994 • 21 citations

Effect of Diabetes on Fast Response to Norepinephrine in Rat Aorta

1992 • 20 citations

Triglyceride-lowering effect of dietary vitamin E in streptozocin-induced diabetic rats. Increased lipoprotein lipase activity in livers of diabetic rats fed high dietary vitamin E

1986 • 20 citations

Effect of diabetes on fast response to norepinephrine in rat aorta

1992 • 15 citations

Effects of PP-56 and vitamin E on platelet hyperaggregability, fatty acid abnormalities, and clinical manifestations in streptozocin-induced diabetic rats

1991 • 12 citations

Vitamin E enhances prostacyclin production by cultured aortic endothelial cells.

1990 • 7 citations

High glucose reduces specific binding for D-alpha-tocopherol in cultured aortic endothelial cells

1993 • 7 citations