Synergistic effect of adoptive T-cell therapy and intratumoral interferon γ-inducible protein-10 transgene expression in treatment of established tumors

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

Interleukin-8 and related chemotactic cytokines--CXC and CC chemokines.

1994 • 2,251 citations

A new class of membrane-bound chemokine with a CX3C motif

1997 • 1,964 citations

Properties of the Novel Proinflammatory Supergene "Intercrine" Cytokine Family

1991 • 1,864 citations

A New Approach to the Adoptive Immunotherapy of Cancer with Tumor-Infiltrating Lymphocytes

1986 • 1,787 citations

lnterleukin-8 and Related Chemotactic Cytokines—CXC and CC Chemokines

1993 • 1,650 citations

CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer.

1998 • 1,175 citations

Treatment of Patients With Metastatic Melanoma With Autologous Tumor-Infiltrating Lymphocytes and Interleukin 2

1994 • 991 citations

Interferon–inducible T Cell Alpha Chemoattractant (I-TAC): A Novel Non-ELR CXC Chemokine with Potent Activity on Activated T Cells through Selective High Affinity Binding to CXCR3

1998 • 857 citations

Mig and IP-10: CXC chemokines that target lymphocytes

1997 • 802 citations

Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity.

1993 • 801 citations

Chemokine and Chemokine Receptor Interactions Provide a Mechanism for Selective T Cell Recruitment to Specific Liver Compartments Within Hepatitis C-Infected Liver

1999 • 426 citations

The next frontier of molecular medicine: Delivery of therapeutics

1998 • 408 citations

Concanamycin A, a powerful tool for characterization and estimation of contribution of perforin- and Fas-based lytic pathways in cell-mediated cytotoxicity.

1996 • 401 citations

How do cytotoxic lymphocytes kill their targets?

1998 • 398 citations

Tumor localization of adoptively transferred indium-111 labeled tumor infiltrating lymphocytes in patients with metastatic melanoma.

1989 • 332 citations

Chemokines, inflammation and the immune system.

1994 • 302 citations

The CC chemokine 6Ckine binds the CXC chemokine receptor CXCR3

1998 • 249 citations

Interferon-inducible protein-10 identified as a mediator of tumor necrosisin vivo

1996 • 223 citations

Localization of111Indium-labeled tumor infiltrating lymphocytes to tumor in patients receiving adoptive immunotherapy. Augmentation with cyclophosphamide and correlation with response

1994 • 201 citations

C‐C chemokines, but not the C‐X‐C chemokines interleukin‐8 and interferon‐γ inducible protein‐10, stimulate transendothelial chemotaxis of T lymphocytes

1995 • 197 citations

Immunizing and curative potential of replicating and nonreplicating murine mammary adenocarcinoma cells engineered with interleukin (IL)-2, IL-4, IL-6, IL-7, IL-10, tumor necrosis factor alpha, granulocyte-macrophage colony-stimulating factor, and gamma-interferon gene or admixed with conventional adjuvants.

1994 • 167 citations

Adoptive immunotherapy with vaccine-primed lymph node cells secondarily activated with anti-CD3 and interleukin-2.

1997 • 167 citations

Intratumoral Coinjection of Two Adenoviruses, One Encoding the Chemokine IFN-γ-Inducible Protein-10 and Another Encoding IL-12, Results in Marked Antitumoral Synergy

2000 • 159 citations

Gene-Modified Tumor Vaccine with Therapeutic Potential Shifts Tumor-Specific T Cell Response from a Type 2 to a Type 1 Cytokine Profile

1998 • 154 citations

Infiltration of tumors by systemically transferred tumor-reactive T lymphocytes is required for antitumor efficacy.

1999 • 115 citations

A Role for the Interferon‐Inducible Protein 10 in Inhibition of Angiogenesis by Interleukin‐12

1996 • 115 citations

Purification of L-Selectinlow Cells Promotes the Generation of Highly Potent CD4 Antitumor Effector T Lymphocytes

1998 • 110 citations

Adenoviral Vectors Expressing Lymphotactin and Interleukin 2 or Lymphotactin and Interleukin 12 Synergize to Facilitate Tumor Regression in Murine Breast Cancer Models

1999 • 105 citations

Clinical observations on adoptive immunotherapy with vaccine-primed T-lymphocytes secondarily sensitized to tumor in vitro.

1993 • 88 citations

Induction of ErbB-2/neu-specific protective and therapeutic antitumor immunity using genetically modified dendritic cells: enhanced efficacy by cotransduction of gene encoding IL-12

2001 • 75 citations

Lymphotactin Expression by Engineered Myeloma Cells Drives Tumor Regression: Mediation by CD4+ and CD8+ T Cells and Neutrophils Expressing XCR1 Receptor

2001 • 73 citations

Fas-dependent CD4⁺cytotoxic T-cell-mediated pathogenesis during virus infection

1996 • 72 citations

Regulation of adhesion molecule expression by CD8 T cells in vivo. II. Expression of L-selectin (CD62L) by memory cytolytic T cells responding to minor histocompatibility antigens.

1994 • 70 citations

Treatment of Murine Gliomas by Adoptive Transfer ofex VivoActivated Tumor-Draining Lymph Node Cells

1997 • 68 citations

Neutrophils and B Cells Express XCR1 Receptor and Chemotactically Respond to Lymphotactin

2001 • 67 citations

Tumor Infiltration by Adoptively Transferred T Cells Is Independent of Immunologic Specificity but Requires Down-Regulation of L-Selectin Expression

1999 • 67 citations

Treatment of Subcutaneous Tumor with Adoptively Transferred T Cells

1997 • 54 citations

Successful Adoptive Immunotherapy of MurinePoorly ImmunogenicTumor with Specific Effector Cells Generated from Gene-Modified Tumor-Primed Lymph Node Cells

1999 • 54 citations

A critical role for a peritumoral stromal reaction in the induction of T-cell migration responsible for interleukin-12-induced tumor regression.

1999 • 51 citations

Protein sorting and secretion during CTL killing

1997 • 42 citations

Intratumoral coinjection of two adenoviral vectors expressing functional interleukin-18 and inducible protein-10, respectively, synergizes to facilitate regression of established tumors

2002 • 38 citations

Adenovirus-mediated TNF-α Gene Transfer induces Significant Tumor Regression in Mice

1999 • 37 citations

Regression of Engineered Tumor Cells Secreting Cytokines Is Related to a Shift in Host Cytokine Profile from Type 2 to Type 1

2000 • 31 citations

Combinational immunotherapy for established tumors with engineered tumor vaccines and adenovirus-mediated gene transfer

2000 • 23 citations