Sequential Binding of Import Ligands to Distinct Nucleopore Regions During Their Nuclear Import

Nuclear targeting sequences — a consensus?

1991 • 1,908 citations

A new method of preparing gold probes for multiple-labeling cytochemistry.

1985 • 1,417 citations

Nucleocytoplasmic Transport

1996 • 1,071 citations

Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins

1995 • 767 citations

The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

1993 • 760 citations

Isolation of a protein that is essential for the first step of nuclear protein import

1994 • 710 citations

Nuclear protein localization

1991 • 570 citations

Nuclear protein migration involves two steps: Rapid binding at the nuclear envelope followed by slower translocation through nuclear pores

1988 • 551 citations

Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor [published erratum appears in J Cell Biol 1994 Jan;124(1-2):217]

1993 • 544 citations

Nuclear import can be separated into distinct steps in vitro: Nuclear pore binding and translocation

1988 • 535 citations

Monoclonal antibodies identify a group of nuclear pore complex glycoproteins.

1987 • 533 citations

Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope

1995 • 511 citations

Movement of a karyophilic protein through the nuclear pores of oocytes.

1984 • 510 citations

The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex

1995 • 460 citations

Architecture and design of the nuclear pore complex

1992 • 452 citations

Architecture of the Xenopus nuclear pore complex revealed by three-dimensional cryo-electron microscopy

1993 • 408 citations

Identification of NTF2, a cytosolic factor for nuclear import that interacts with nuclear pore complex protein p62.

1995 • 385 citations

Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes

1995 • 350 citations

Purification of a Ran-interacting protein that is required for protein import into the nucleus.

1994 • 318 citations

Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope.

1994 • 306 citations

Toward a more complete 3-D structure of the nuclear pore complex

1991 • 254 citations

Mechanisms of nuclear protein import

1995 • 241 citations

The GLFG repetitive region of the nucleoporin Nup116p interacts with Kap95p, an essential yeast nuclear import factor.

1995 • 206 citations

Role of the Nuclear Transport Factor p10 in Nuclear Import

1996 • 166 citations

Small colloidal gold conjugated to fab fragments or to immunoglobulin g as high‐resolution labels for electron microscopy: A technical overview

1990 • 137 citations

Telomere length and proliferation potential of hematopoietic stem cells

1995 • 117 citations

Tpr, a large coiled coil protein whose amino terminus is involved in activation of oncogenic kinases, is localized to the cytoplasmic surface of the nuclear pore complex.

1994 • 114 citations

Toward the molecular dissection of protein import into nuclei

1996 • 112 citations

Towards understanding the three-dimensional structure of the nuclear pore complex at the molecular level

1994 • 65 citations

Exploring nuclear pore complex structure and function in molecular detail

1995 • 60 citations

Toward a Molecular Understanding of the Structure and Function of the Nuclear Pore Complex

1996 • 50 citations

Isolation of a yeast protein kinase that is activated by the protein encoded by SRP1 (Srp1p) and phosphorylates Srp1p complexed with nuclear localization signal peptides.

1995 • 29 citations

Core-hole migration and relaxation effect in alkali halide excited by synchrotron radiation

1992 • 29 citations