Identification of a cold receptor reveals a general role for TRP channels in thermosensation

The capsaicin receptor: a heat-activated ion channel in the pain pathway

1997 • 8,634 citations

Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor

2000 • 3,436 citations

Textbook of pain

1999 • 2,566 citations

Molecular mechanisms of nociception

2001 • 2,564 citations

Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide

1999 • 2,128 citations

Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia

2000 • 1,715 citations

A capsaicin-receptor homologue with a high threshold for noxious heat

1999 • 1,547 citations

Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition

2001 • 1,240 citations

The trp ion channel family

2001 • 1,108 citations

Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances

2000 • 1,048 citations

Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli.

1969 • 1,011 citations

New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor

1994 • 924 citations

ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

2001 • 877 citations

Induction of vanilloid receptor channel activity by protein kinase C

2000 • 814 citations

TRP-PLIK, a Bifunctional Protein with Kinase and Ion Channel Activities

2001 • 714 citations

Acid potentiation of the capsaicin receptor determined by a key extracellular site

2000 • 620 citations

Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins.

2001 • 597 citations

From worm to man: three subfamilies of TRP channels

2000 • 490 citations

Menthol and Related Cooling Compounds

1994 • 481 citations

The Thermal Grill Illusion: Unmasking the Burn of Cold Pain

1994 • 467 citations

A novel heat-activated current in nociceptive neurons and its sensitization by bradykinin

1996 • 435 citations

Immunocyte Ca ²⁺ Influx System Mediated by LTRPC2

2001 • 434 citations

Ion‐concentration dependence of the reversal potential and the single channel conductance of ion channels at the frog neuromuscular junction.

1979 • 394 citations

Responsiveness and functional attributes of electrically localized terminals of cutaneous C-fibers in vivo and in vitro

1992 • 259 citations

Response Properties of Mechanoreceptors and Nociceptors in Mouse Glabrous Skin: An In Vivo Study

2001 • 223 citations

RELEASE OF COLD-INDUCED BURNING PAIN BY BLOCK OF COLD-SPECIFIC AFFERENT INPUT

1990 • 223 citations

The Effect of Menthol on the Thermoreceptors

1951 • 217 citations

Response characteristics of cutaneous warm receptors in the monkey

1980 • 203 citations

Slowly conducting afferents activated by innocuous low temperature in human skin

2001 • 193 citations

Responses of Cutaneous A-Fiber Nociceptors to Noxious Cold

1997 • 191 citations

Central suppression of cold-induced C fibre pain by myelinated fibre input

1989 • 177 citations

Cold current in thermoreceptive neurons

2001 • 173 citations

DEG/ENaC ion channels involved in sensory transduction are modulated by cold temperature

2001 • 171 citations

Effect of menthol on cold receptor activity. Analysis of receptor processes.

1986 • 152 citations

Static and dynamic discharge patterns of bursting cold fibers related to hypothetical receptor mechanisms

1980 • 149 citations

Noxious heat activates all capsaicin-sensitive and also a sub-population of capsaicin-insensitive dorsal root ganglion neurons

1999 • 147 citations

Response characteristics of cutaneous cold receptors in the monkey

1977 • 124 citations

Cold transduction by inhibition of a background potassium conductance in rat primary sensory neurones

2001 • 123 citations

Role of cold receptors and menthol in thirst, the drive to breathe and arousal

2000 • 118 citations

Effect of menthol on two types of Ca currents in cultured sensory neurons of vertebrates

1987 • 111 citations

Excitation of rat cutaneous nociceptors by noxious cold

1996 • 109 citations

AG-3–5: a chemical producing sensations of cold

1983 • 102 citations

The Discharge of Specific, Cold Fibres at High Temperatures

1952 • 101 citations

Mammalian cold receptor afferents: role of an electrogenic sodium pump in sensory transduction

1974 • 75 citations

Isolation and culture of rat sensory neurons having distinct sensory modalities

1997 • 68 citations

l-Menthol-induced [Ca2+]i increase and impulses in cultured sensory neurons

2000 • 54 citations

Calcium signaling in cold cells studied in cultured dorsal root ganglion neurons

1999 • 53 citations

Pharmacological aspects of shaking behavior produced by TRH, AG-3-5, and morphine withdrawal.

1981 • 43 citations

Psychophysical study of noxious and innocuous cold discrimination in monkey

1999 • 21 citations

Effect of Menthol on Cytosolic Ca2+ Levels in Canine Airway Epithelium in Culture

1994 • 20 citations