Induction of vanilloid receptor channel activity by protein kinase C

The capsaicin receptor: a heat-activated ion channel in the pain pathway

1997 • 8,634 citations

Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor

2000 • 3,436 citations

The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli

1998 • 3,026 citations

The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C

1991 • 2,499 citations

Optimized survival of hippocampal neurons in B27‐supplemented neurobasal™, a new serum‐free medium combination

1993 • 2,272 citations

Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide

1999 • 2,128 citations

Vanilloid (Capsaicin) receptors and mechanisms.

1999 • 1,825 citations

Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia

2000 • 1,715 citations

Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances

2000 • 1,048 citations

Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human

2000 • 798 citations

The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1)

2000 • 766 citations

Capsaicin-induced ion fluxes in dorsal root ganglion cells in culture

1988 • 558 citations

Patch clamp measurements onXenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels

1986 • 534 citations

A Novel Nociceptor Signaling Pathway Revealed in Protein Kinase C ε Mutant Mice

1999 • 439 citations

A novel heat-activated current in nociceptive neurons and its sensitization by bradykinin

1996 • 435 citations

Specific Involvement of PKC-ε in Sensitization of the Neuronal Response to Painful Heat

1999 • 414 citations

Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats

1996 • 296 citations

Second messengers involved in the mechanism of action of bradykinin in sensory neurons in culture

1989 • 249 citations

Capsaicin activates a nonselective cation channel in cultured neonatal rat dorsal root ganglion neurons.

1996 • 208 citations

Capsaicin activates a nonselective cation channel in cultured neonatal rat dorsal root ganglion neurons

1996 • 196 citations

Ruthenium red blocks the capsaicin-induced increase in intracellular calcium and activation of membrane currents in sensory neurones as well as the activation of peripheral nociceptors in vitro

1990 • 169 citations

Bradykinin-induced stimulation of afferent fibres is mediated through protein kinase C

1988 • 96 citations

Activation of Protein Kinase C Augments Peptide Release from Rat Sensory Neurons

1996 • 92 citations

Heat-induced release of CGRP from isolated rat skin and effects of bradykinin and the protein kinase C activator PMA

1999 • 77 citations

Bradykinin‐induced depolarization of primary afferent nerve terminals in the neonatal rat spinal cord in vitro

1990 • 43 citations

Anandamide, an endogenous cannabinomimetic substance, modulates rat brain protein kinase C in vitro.

1995 • 36 citations

Evidence that protein kinase C activation is involved in the excitatory and facilitatory effects of bradykinin on canine visceral nociceptors in vitro

1997 • 25 citations

Activation of protein kinase C enhances peptide release from rat spinal cord slices

1999 • 20 citations