Selection of intraepithelial lymphocytes with CD8 alpha/alpha co-receptors by self-antigen in the murine gut.

T cell tolerance by clonal elimination in the thymus

1987 • 2,248 citations

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

1988 • 1,711 citations

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

T-cell receptor Vβ use predicts reactivity and tolerance to Mlsa- encoded antigens

1988 • 901 citations

Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors.

1989 • 778 citations

Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

1988 • 671 citations

Positive selection of antigen-specific T cells in thymus by restricting MHC molecules

1988 • 618 citations

Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation.

1991 • 599 citations

The mouse gut T lymphocyte, a novel type of T cell. Nature, origin, and traffic in mice in normal and graft-versus-host conditions.

1978 • 422 citations

Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice

1991 • 368 citations

Intraepithelial lymphocytes. Anatomical site, not T cell receptor form, dictates phenotype and function.

1989 • 356 citations

The V beta repertoire of mouse gut homodimeric alpha CD8+ intraepithelial T cell receptor alpha/beta + lymphocytes reveals a major extrathymic pathway of T cell differentiation.

1991 • 345 citations

Extrathymic origin of intestinal intraepithelial lymphocytes bearing T-cell antigen receptor gamma delta.

1991 • 262 citations

Expression of Murine CD1 on Gastrointestinal Epithelium

1990 • 231 citations

Deletion of autospecific T cells in T cell receptor (TCR) transgenic mice spares cells with normal TCR levels and low levels of CD8 molecules.

1989 • 231 citations

Cytotoxic differentiation of mouse gut thymodependent and independent intraepithelial T lymphocytes is induced locally. Correlation between functional assays, presence of perforin and granzyme transcripts, and cytoplasmic granules.

1991 • 183 citations

αβ lineage-specific expression of the α T cell receptor gene by nearby silencers

1989 • 182 citations

Expression of the thymus leukemia antigen in mouse intestinal epithelium.

1990 • 161 citations

An unusual lineage of alpha/beta T cells that contains autoreactive cells.

1991 • 152 citations

The appearance of T cells bearing self-reactive T cell receptor in the livers of mice injected with bacteria.

1991 • 145 citations

Gut injury in mouse graft-versus-host reaction. Study of its occurrence and mechanisms.

1986 • 135 citations

T-cell receptor gamma delta and gamma transgenic mice suggest a role of a gamma gene silencer in the generation of alpha beta T cells.

1990 • 128 citations

Highly restricted expression of the thymus leukemia antigens on intestinal epithelial cells.

1991 • 112 citations

Different expression of the recombination activity gene RAG‐1 in various populations of thymocytes, peripheral T cells and gut thymus‐independent intraepithelial lymphocytes suggests two pathways of T cell receptor rearrangement

1992 • 107 citations

Developmentally regulated fetal thymic and extrathymic T-cell receptor gamma delta gene expression.

1990 • 99 citations

Thymic Requirement for Clonal Deletion During T Cell Development

1989 • 95 citations

Control of γδ T‐Cell Development

1991 • 93 citations

Phenotypic and functional analysis of murine CD3+,CD4-,CD8- TCR-gamma delta-expressing peripheral T cells.

1989 • 93 citations

Self-tolerance to transgenic γδ T cells by intrathymic inactivation

1990 • 87 citations

Blockade of transgenic gamma delta T cell development in beta 2-microglobulin deficient mice.

1992 • 83 citations

T cell antigen receptor expression in athymic (nu/nu) mice. Evidence for an oligoclonal beta chain repertoire.

1987 • 81 citations

Characterization of V_β‐bearing cells in athymic (nu/nu) mice suggests an extrathymic pathway for T cell differentiation

1990 • 41 citations

Presence of intestinal intraepithelial lymphocytes in mice with severe combined immunodeficiency disease

1990 • 37 citations

Extrathymic positive selection of gamma delta T cells. V gamma 4J gamma 1 rearrangements with "GxYS" junctions.

1991 • 31 citations

In vivo and in vitro repertoire of CD3⁺CD4−CD8–thymocytes

1990 • 17 citations