Superoxide dismutase and catalase as therapeutic agents for human diseases a critical review

Oxygen-Derived Free Radicals in Postischemic Tissue Injury

1985 • 5,488 citations

Oxygen Radicals and Human Disease

1987 • 1,854 citations

Superoxide dismutase and catalase conjugated to polyethylene glycol increases endothelial enzyme activity and oxidant resistance.

1988 • 425 citations

Oxygen Radicals in Influenza-Induced Pathogenesis and Treatment with Pyran Polymer-Conjugated SOD

1989 • 420 citations

Protective effects of liposome‐entrapped superoxide dismutase on posttraumatic brain edema

1987 • 283 citations

Free Radicals and Their Involvement During Long-Term Myocardial Ischemia and Reperfusion

1990 • 259 citations

Medical, biochemical and chemical aspects of free radicals

1990 • 229 citations

Reperfusion injury

1988 • 191 citations

Prostaglandin-E1 for Interrupted Aortic-Arch in Neonate

1976 • 151 citations

Free radical‐induced pathology

1985 • 150 citations

Iron, Plasma Antioxidants, and the 'Oxygen Radical Disease of Prematurity'

1988 • 144 citations

Prevention of bronchopulmonary dysplasia by administration of bovine superoxide dismutase in preterm infants with respiratory distress syndrome

1984 • 143 citations

Oxygen radicals: a commonsense look at their nature and medical importance.

1984 • 127 citations

Superoxide dismutase for therapeutic use: Clinical experience, dead ends and hopes

1988 • 115 citations

Genetically Engineered Polymers of Human CuZn Superoxide Dismutase

1989 • 90 citations

Liposome-mediated augmentation of brain SOD and catalase inhibits CNS O2 toxicity

1984 • 85 citations

Cationization of catalase, peroxidase, and superoxide dismutase. Effect of improved intraarticular retention on experimental arthritis in mice.

1985 • 83 citations

Phase II trial of copper zinc superoxide dismutase (CuZnSOD) in treatment of Crohn's disease

1989 • 82 citations

Reperfusion and reperfusion injury.

1987 • 82 citations

Synthesis of a superoxide dismutase derivative that circulates bound to albumin and accumulates in tissues whose pH is decreased

1989 • 79 citations

Improved Survival of Island Flaps after Prolonged Ischemia by Perfusion with Superoxide Dismutase

1986 • 78 citations

Scientific basis for the clinical use of superoxide dismutase

1986 • 66 citations

Intra-articular orgotein in osteoarthritis of the knee: A placebo-controlled efficacy, safety, and dosage comparison

1989 • 51 citations

Drug Trial of Superoxide Dismutase in Duchenne's Muscular Dystrophy

1982 • 46 citations

Paraquat suicide in a young woman: results of therapy directed against the superoxide radical.

1977 • 42 citations

Therapeutic benefits of oxygen radical scavenger treatments remain unproven

1985 • 40 citations

Effects of Superoxide Dismutase and Catalase on Disseminated Intravascular Coagulation In Rats

1983 • 40 citations

Anti-Shock Effects of Human Superoxide Dismutase in Splanchnic Artery Occlusion (SAO) Shock

1988 • 39 citations

Superoxide Radical Scavenging Agents in Treatment of Alkali Burns

1981 • 36 citations

Anticancer activity of metal compounds with superoxide dismutase activity

1984 • 34 citations

Modulation of Lens-Induced Uveitis by Superoxide Dismutase

1986 • 28 citations

Approaches to prevention of asbestos-induced lung disease using polyethylene glycol (PEG)-conjugated catalase

1986 • 28 citations

Superoxide dismutase in the treatment of post-radiotherapeutic necrosis and of Crohn's disease.

1981 • 24 citations

Influence of antioxidant enzymes in reduction of optic disc edema in experimental optic neuritis

1986 • 24 citations

Administration of bovine superoxide dismutase prevents sequelae of spinal cord ischemia in the rabbit

1989 • 22 citations

Safety and Plasma Concentrations of Bovine Superoxide Dismutase Administered to Human Premature Infants

1982 • 21 citations

Fate of superoxide dismutase in mice following oral route of administration.

1984 • 20 citations

Oxidant-mediated lung disease in newborn infants

1986 • 17 citations

Effects of superoxide dismutase and catalase on central nervous system toxicity of hyperbaric oxygen

1980 • 15 citations

Effect of superoxide dismutase and succinate on the development of hyperbaric oxygen toxicity.

1977 • 15 citations

The pathogenic role of superoxide radicals in inflammation: efficacy of exogenous superoxide dismutase.

1981 • 14 citations

Pathogenesis, diagnosis and therapy of induratio penis plastica (IPP)

1985 • 14 citations

Bovine superoxide dismutase in Fanconi anaemia. Therapeutic trial in two patients

1985 • 10 citations

Oxygen free radicals and duodenal ulcer pain. Preliminary data.

1987 • 10 citations

Anti-shock effects of human superoxide dismutase in splanchnic artery occlusion (SAO) shock

1989 • 9 citations

Clinical efficacy of a new antiinflammatory drug with free radicals scavenging properties: superoxide dismutase (SOD) and catalase of human origin.

1986 • 7 citations

Failure of heparin, superoxide dismutase, and catalase to protect against decompression sickness.

1987 • 6 citations

[New therapy for Peyronie's disease: superoxide dismutase by ionization. Comparison with an earlier classical series].

1988 • 4 citations

Purity of catalase preparations: Contamination by endotoxin and its role in the inhibition of airway inflammation

1986 • 4 citations

Evaluation of Superoxide Dismutase (Orgotein) in Medical Treatment of Canine Cataract

1982 • 4 citations

[Superoxide dismutase in ischemic phenomena in the human. Obstruction by strangulation and cutaneous flaps].

1987 • 3 citations

Effect of liposomal encapsulated superoxide dismutase on patients with Kawasaki disease.

1987 • 3 citations

Epurox in the treatment of juvenile rheumatoid arthritis.

1986 • 2 citations

Local treatment with Epurox (superoxide dismutase and catalase of human origin) in the chronic inflammatory and degenerative rheumatism.

1986 • 2 citations

[Superoxide dismutase in general surgery. Preliminary results].

1986 • 1 citations

Deleted Work

1955 • 0 citations