The inheritance of intermediate phenotypes for schizophrenia

The Endophenotype Concept in Psychiatry: Etymology and Strategic Intentions

2003 • 5,516 citations

Effect of COMT Val ^108/158 Met genotype on frontal lobe function and risk for schizophrenia

2001 • 2,408 citations

Differential Effects of Early Hippocampal Pathology on Episodic and Semantic Memory

1997 • 1,742 citations

Structure and function of declarative and nondeclarative memory systems

1996 • 1,298 citations

Disruption of two novel genes by a translocation co-segregating with schizophrenia

2000 • 1,250 citations

A General Test of Association for Quantitative Traits in Nuclear Families

2000 • 1,160 citations

Genetic and physiological data implicating the new human gene G72 and the gene for <scp>d</scp> -amino acid oxidase in schizophrenia

2002 • 828 citations

Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia

2002 • 824 citations

Association within a family of a balanced autosomal translocation with major mental illness

1990 • 730 citations

Prefrontal Dopamine D₁Receptors and Working Memory in Schizophrenia

2002 • 724 citations

Functional and Anatomical Aspects of Prefrontal Pathology in Schizophrenia

1997 • 665 citations

Architecture of the Prefrontal Cortex and the Central Executive

1995 • 636 citations

Executive Subprocesses in Working Memory

2003 • 591 citations

The Genetics of Schizophrenia: A Current, Genetic-epidemiologic Perspective

1993 • 572 citations

Abnormal fMRI Response of the Dorsolateral Prefrontal Cortex in Cognitively Intact Siblings of Patients With Schizophrenia

2003 • 447 citations

Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia

2004 • 410 citations

Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia

2004 • 389 citations

The Inheritance of Neuropsychological Dysfunction in Twins Discordant for Schizophrenia

2000 • 375 citations

DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation

2003 • 374 citations

Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophrenia

2004 • 353 citations

Haplotype transmission analysis provides evidence of association for DISC1 to schizophrenia and suggests sex-dependent effects

2003 • 325 citations

Chromosome 1 loci in Finnish schizophrenia families

2001 • 315 citations

Cortex mapping reveals regionally specific patterns of genetic and disease-specific gray-matter deficits in twins discordant for schizophrenia

2002 • 315 citations

Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth

2003 • 312 citations

Spatial working memory as an endophenotype for schizophrenia

2003 • 282 citations

Left Hippocampal Volume as a Vulnerability Indicator for Schizophrenia

2002 • 264 citations

Prefrontal Broadband Noise, Working Memory, and Genetic Risk for Schizophrenia

2004 • 244 citations

The recognition of facial affect in autistic and schizophrenic subjects and their first-degree relatives

2003 • 236 citations

Contributions of Genetic Risk and Fetal Hypoxia to Hippocampal Volume in Patients With Schizophrenia or Schizoaffective Disorder, Their Unaffected Siblings, and Healthy Unrelated Volunteers

2002 • 226 citations

Genome-wide scan for schizophrenia in the Finnish population: evidence for a locus on chromosome 7q22

2000 • 210 citations

Relationship of Obstetric Complications and Differences in Size of Brain Structures in Monozygotic Twin Pairs Discordant for Schizophrenia

2000 • 207 citations

Neuropsychologic functioning among the nonpsychotic relatives of schizophrenic patients: the effect of genetic loading

2000 • 200 citations

Duration mismatch negativity in biological relatives of patients with schizophrenia spectrum disorders

2002 • 186 citations

Replication of 1q42 linkage in Finnish schizophrenia pedigrees

2004 • 185 citations

Suggestive Linkage to Chromosomal Regions 13q31 and 22q12 in Families With Psychotic Bipolar Disorder

2003 • 183 citations

Disrupted in Schizophrenia 1 (DISC1) is a multicompartmentalized protein that predominantly localizes to mitochondria

2004 • 154 citations

The genetics of sensory gating deficits in schizophrenia

2003 • 153 citations

Genome scan of pedigrees multiply affected with bipolar disorder provides further support for the presence of a susceptibility locus on chromosome 12q23-q24, and suggests the presence of additional loci on 1p and 1q

2003 • 152 citations

Hippocampal Volumes in Schizophrenic Twins

2004 • 149 citations

Neuropsychological assessment of young people at high genetic risk for developing schizophrenia compared with controls: preliminary findings of the Edinburgh High Risk Study (EHRS)

1999 • 140 citations

Deficits in Gain of Smooth Pursuit Eye Movements in Schizophrenia and Affective Disorder Patients and Their Unaffected Relatives

2003 • 133 citations

Linkage of schizophrenia with chromosome 1q loci in Taiwanese families

2003 • 132 citations

Bipolar Disorder and Schizophrenia: Convergent Molecular Data

2004 • 124 citations

Mismatch negativity in schizophrenia: a family study

2003 • 116 citations

Neurobiological Measures of Schizotypal Personality Disorder: Defining an Inhibitory Endophenotype?

2002 • 115 citations

P300 and Genetic Risk for Schizophrenia

2003 • 111 citations

Amygdala–hippocampal volume and verbal memory in first-degree relatives of schizophrenic patients

2001 • 108 citations

P300 subcomponent abnormalities in schizophrenia: III. Deficits in unaffected siblings of schizophrenic probands

2000 • 104 citations

Smooth pursuit and antisaccade eye movements in siblings discordant for schizophrenia

2003 • 103 citations

A Twin Study of Genetic Contributions to Hippocampal Morphology in Schizophrenia

2002 • 100 citations

Antisaccade performance is impaired in medically and psychiatrically healthy biological relatives of schizophrenia patients

2004 • 95 citations

The −2 bp deletion in exon 6 of the ‘alpha 7-like’ nicotinic receptor subunit gene is a risk factor for the P50 sensory gating deficit

2002 • 95 citations

Search for cognitive trait components of schizophrenia reveals a locus for verbal learning and memory on 4q and for visual working memory on 2q

2004 • 90 citations

Genetic linkage and association between chromosome 1q and working memory function in schizophrenia

2002 • 88 citations

Relationship between magnitude of damage to the hippocampus and impaired recognition memory in monkeys

2001 • 87 citations

P50 sensory gating in adolescents from a pacific island isolate with elevated risk for schizophrenia

2004 • 86 citations

Vernier Threshold in Patients With Schizophrenia and in Their Unaffected Siblings.

2004 • 86 citations

Familial loading associates with impairment in visual span among healthy siblings of schizophrenia patients

2003 • 79 citations

Genomewide Linkage Disequilibrium Mapping of Severe Bipolar Disorder in a Population Isolate

2002 • 71 citations

The promoter −194 C polymorphism of the nicotinic alpha 7 receptor gene has a protective effect against the P50 sensory gating deficit

2003 • 68 citations

Clinical phenotypes associated with DISC1, a candidate gene for schizophrenia

2004 • 67 citations

Do schizotypal symptoms mediate the relationship between genetic risk for schizophrenia and impaired neuropsychological performance in co-twins of schizophrenic patients?

2003 • 58 citations

Quantitative neural indicators of liability to schizophrenia: Implications for molecular genetic studies

2001 • 54 citations

Molecular Brain Imaging and the Neurobiology and Genetics of Schizophrenia

2003 • 52 citations

Early Expression of a Pathophysiological Feature of Schizophrenia: Saccadic Intrusions Into Smooth-Pursuit Eye Movements in School-Age Children Vulnerable to Schizophrenia

2003 • 41 citations

Subjective Experience of Schizotropic Vulnerability in Siblings of Schizophrenics

2004 • 37 citations

Elucidating continuities and discontinuities between schizotypy and schizophrenia in the nervous system

2002 • 37 citations

Secondary verbal memory: a potential endophenotype of schizophrenia

2004 • 36 citations

Association of EEG coherence and an exonic GABA_BR1 gene polymorphism

2002 • 33 citations

Gray matter features of schizotypal disorder patients exhibiting the schizophrenia‐related code types of the Minnesota Multiphasic Personality Inventory

2003 • 26 citations