Comparison of the effects of AT1 receptor blockade and angiotensin converting enzyme inhibition on atherosclerosis

Effect of Captopril on Mortality and Morbidity in Patients with Left Ventricular Dysfunction after Myocardial Infarction

1992 • 5,885 citations

Effect of Enalapril on Mortality and the Development of Heart Failure in Asymptomatic Patients with Reduced Left Ventricular Ejection Fractions

1992 • 3,708 citations

Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.

1994 • 2,753 citations

Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.

1996 • 2,456 citations

Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure

1993 • 1,775 citations

Randomised trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study, ELITE)

1997 • 1,680 citations

Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators.

1993 • 1,240 citations

Inhibitors of Angiotensin-Converting Enzyme Prevent Myointimal Proliferation After Vascular Injury

1989 • 1,061 citations

Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress.

1996 • 851 citations

Antiatherogenic effects of L-arginine in the hypercholesterolemic rabbit.

1992 • 697 citations

Induction of platelet-derived growth factor A-chain and c-myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells.

1989 • 632 citations

Increased Accumulation of Tissue ACE in Human Atherosclerotic Coronary Artery Disease

1996 • 431 citations

Antiatherogenic effect of captopril in the Watanabe heritable hyperlipidemic rabbit.

1990 • 419 citations

Angiotensin induction of PAI-1 expression in endothelial cells is mediated by the hexapeptide angiotensin IV.

1995 • 303 citations

Stimulation of endothelin mRNA and secretion in rat vascular smooth muscle cells: a novel autocrine function.

1990 • 271 citations

Flow stimulates endothelial cells to release a nitrovasodilator that is potentiated by reduced thiol

1990 • 260 citations

Role of kinins and nitric oxide in the effects of angiotensin converting enzyme inhibitors on neointima formation.

1993 • 233 citations

Effects of Captopril on Atherosclerosis in Cynomolgus Monkeys

1990 • 187 citations

Pharmacological characterization of SR 47436, a new nonpeptide AT1 subtype angiotensin II receptor antagonist.

1993 • 182 citations

Suppression of Angiotensin-Converting Enzyme Expression and Activity by Shear Stress

1997 • 145 citations

Trandolapril inhibits atherosclerosis in the Watanabe heritable hyperlipidemic rabbit.

1992 • 119 citations

Angiotensin II Increases Macrophage-mediated Modification of Low Density Lipoprotein via a Lipoxygenase-dependent Pathway

1997 • 117 citations

Differential effects of renin-angiotensin system blockade on atherogenesis in cholesterol-fed rabbits.

1993 • 113 citations

Inhibitors of angiotensin converting enzyme decrease early atherosclerosis in hyperlipidemic hamsters. Fosinopril reduces plasma cholesterol and captopril inhibits macrophage—foam cell accumulation independently of blood pressure and plasma lipids

1994 • 92 citations

Does nifedipine suppress atherogenesis in WHHL rabbits?

1984 • 67 citations

ACE inhibition with perindopril and atherogenesis-induced structural and functional changes in minipig arteries.

1993 • 57 citations

Failure of a slow channel calcium antagonist, verapamil, to retard atherosclerosis in the watanabe heritable hyperlipidemic rabbit: An animal model of familial hypercholesterolemia

1985 • 55 citations

The effects of renin-angiotensin system inhibition on aortic cholesterol content in cholesterol-fed rabbits

1996 • 34 citations

Dissociation Between the Antiatherosclerotic Effect of Trandolapril and Suppression of Serum and Aortic Angiotensin-Converting Enzyme Activity in the Watanabe Heritable Hyperlipidemic Rabbit

1995 • 27 citations