Predicting adaptive evolution

CONFIDENCE LIMITS ON PHYLOGENIES: AN APPROACH USING THE BOOTSTRAP

1985 • 39,646 citations

Molecular Evolution and Phylogenetics

2000 • 7,148 citations

Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions.

1986 • 4,940 citations

Codon-Substitution Models for Heterogeneous Selection Pressure at Amino Acid Sites

2000 • 2,298 citations

Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection

1988 • 1,968 citations

Statistical methods for detecting molecular adaptation

2000 • 1,769 citations

Fundamentals of molecular evolution

1991 • 1,721 citations

Likelihood Models for Detecting Positively Selected Amino Acid Sites and Applications to the HIV-1 Envelope Gene

1998 • 1,615 citations

Options for the control of influenza III

1997 • 591 citations

Predicting the Evolution of Human Influenza A

1999 • 524 citations

A method for detecting positive selection at single amino acid sites

1999 • 516 citations

Long term trends in the evolution of H(3) HA1 human influenza type A

1997 • 403 citations

Different Trajectories of Parallel Evolution During Viral Adaptation

1999 • 380 citations

Positive selection and sequence rearrangements generate extensive polymorphism in the gamete recognition protein bindin

1996 • 370 citations

Rapid evolution in plant chitinases: Molecular targets of selection in plant-pathogen coevolution

2000 • 364 citations

Positive selection on the H3 hemagglutinin gene of human influenza virus A

1999 • 360 citations

All males are not created equal: Fertility differences depend on gamete recognition polymorphisms in sea urchins

1999 • 325 citations

Positive Darwinian evolution in human influenza A viruses.

1991 • 322 citations

Xa21D Encodes a Receptor-like Molecule with a Leucine-Rich Repeat Domain That Determines Race-Specific Recognition and Is Subject to Adaptive Evolution

1998 • 319 citations

CD4-Induced Conformational Changes in the Human Immunodeficiency Virus Type 1 gp120 Glycoprotein: Consequences for Virus Entry and Neutralization

1998 • 292 citations

Receptor-like Genes in the Major Resistance Locus of Lettuce Are Subject to Divergent Selection

1998 • 279 citations

Maximum Likelihood Estimation on Large Phylogenies and Analysis of Adaptive Evolution in Human Influenza Virus A

2000 • 261 citations

Maximum-Likelihood Analysis of Molecular Adaptation in Abalone Sperm Lysin Reveals Variable Selective Pressures Among Lineages and Sites

2000 • 246 citations

Positive selection is a general phenomenon in the evolution of abalone sperm lysin.

1995 • 236 citations

Rapid evolution of fertilization selectivity and lysin cDNA sequences in teguline gastropods

1999 • 169 citations

The molecular evolution of sperm bindin in six species of sea urchins (Echinoida: Strongylocentrotidae)

1998 • 143 citations

Positive darwinian selection on two homologous fertilization proteins: what is the selective pressure driving their divergence?

1997 • 134 citations

Evolution subverting essentiality: Dispensability of the cell attachment Arg-Gly-Asp motif in multiply passaged foot-and-mouth disease virus

1997 • 129 citations

Experimental evolution recapitulates natural evolution

2000 • 105 citations

Sequence evolution of the porB gene of Neisseria gonorrhoeae and Neisseria meningitidis: evidence of positive Darwinian selection.

1995 • 103 citations

Reevaluation of Amino Acid Variability of the Human Immunodeficiency Virus Type 1 gp120 Envelope Glycoprotein and Prediction of New Discontinuous Epitopes

2000 • 98 citations

Statistical analysis of nucleotide sequences of the hemagglutinin gene of human influenza A viruses.

1994 • 94 citations

Identification of regions in which positive selection may operate in S‐RNase of Rosaceae: Implication for S‐allele‐specific recognition sites in S‐RNase

1998 • 90 citations

Effects of passage history and sampling bias on phylogenetic reconstruction of human influenza A evolution

2000 • 79 citations

Abalone lysin: the dissolving and evolving sperm protein

2000 • 74 citations

Convergent evolution within the V3 loop domain of human immunodeficiency virus type 1 in association with disease progression

1995 • 62 citations

A procedure for detecting selection in highly variable viral genomes: evidence of positive selection in antigenic regions of capsid protein VP1 of foot-and-mouth disease virus

1998 • 24 citations