Different Trajectories of Parallel Evolution During Viral Adaptation

Adaptive protein evolution at the Adh locus in Drosophila

1991 • 3,323 citations

Nucleotide sequence of bacteriophage G4 DNA

1978 • 2,137 citations

Nucleotide sequence of bacteriophage φX174 DNA

1977 • 1,475 citations

Dynamics of adaptation and diversification: a 10,000-generation experiment with bacterial populations.

1994 • 1,007 citations

The fate of competing beneficial mutations in an asexual population

1998 • 797 citations

Untitled

1998 • 790 citations

Ordered accumulation of mutations in HIV protease confers resistance to ritonavir

1996 • 776 citations

Fitness of RNA virus decreased by Muller's ratchet

1990 • 498 citations

Episodic adaptive evolution of primate lysozymes

1997 • 476 citations

Exceptional Convergent Evolution in a Virus

1997 • 380 citations

Adaptive evolution in the stomach lysozymes of foregut fermenters

1987 • 376 citations

Microbial evolution in a simple unstructured environment: genetic differentiation in Escherichia coli.

1994 • 370 citations

Ordered Appearance of Zidovudine Resistance Mutations during Treatment of 18 Human Immunodeficiency Virus-Positive Subjects

1992 • 369 citations

Punctuated Evolution Caused by Selection of Rare Beneficial Mutations

1996 • 352 citations

The Single-Stranded DNA Phages

1975 • 301 citations

Exponential increases of RNA virus fitness during large population transmissions.

1995 • 278 citations

Metabolic Flux and Fitness

1987 • 245 citations

Stochastic processes strongly influence HIV-1 evolution during suboptimal protease-inhibitor therapy

1998 • 163 citations

Evolution of multiple genome mutations during long-term persistent infection by vesicular stomatitis virus

1979 • 157 citations

Resistance of human immunodeficiency virus type 1 to protease inhibitors: selection of resistance mutations in the presence and absence of the drug

1996 • 157 citations

Zidovudine treatment results in the selection of human immunodeficiency virus type 1 variants whose genotypes confer increasing levels of drug resistance

1994 • 98 citations

A Population Genetic Test of Selection at the Molecular Level

1995 • 78 citations

Biology of the Bacteriophage φX174

1988 • 61 citations

Molecular Diversity and Evolution of bla TEM Genes Encoding β-Lactamases Resistant to Clavulanic Acid in Clinical E. coli

1997 • 59 citations

Diversifying Selection Governs Sequence Polymorphism in the Major Adhesin Proteins FimA, PapA, and SfaA of Escherichia coli

1998 • 41 citations

Nucleotide sequence and genome organization of bacteriophage S13 DNA

1985 • 25 citations