Loss of the MYC gene amplified in human HL-60 cells after treatment with inhibitors of poly(ADP-ribose) polymerase or with dimethyl sulfoxide.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis

1984 • 2,847 citations

The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression

1987 • 1,180 citations

The nucleotide sequence of the rat cytoplasmic β–actin gene

1983 • 1,059 citations

A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells

1986 • 834 citations

Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma.

1983 • 764 citations

Gene amplification in cultured animal cells

1984 • 639 citations

GENE AMPLIFICATION

1984 • 580 citations

Expression of cellular homologues of retroviral onc genes in human hematopoietic cells.

1982 • 570 citations

Transcriptional arrest within the first exon is a fast control mechanism in c-myc gene expression

1986 • 254 citations

Inhibitors of poly(adenosine diphosphate ribose) polymerase induce sister chromatid exchanges

1980 • 236 citations

Double minute chromosomes can be produced from precursors derived from a chromosomal deletion.

1988 • 236 citations

Poly (ADP-Ribose) synthetase. Separation and identification of three proteolytic fragments as the substrate-binding domain, the DNA-binding domain, and the automodification domain.

1984 • 226 citations

Poly(adenosine diphosphate ribose)

1973 • 210 citations

Human DNA sequence homologous to the transforming gene (mos) of Moloney murine sarcoma virus.

1982 • 193 citations

DNA Sequence Amplification in Mammalian Cells

1984 • 181 citations

Association of amplified oncogene c-myc with an abnormally banded chromosome 8 in a human leukaemia cell line

1983 • 152 citations

Amplified human MYC oncogenes localized to replicating submicroscopic circular DNA molecules.

1988 • 137 citations

ADP-ribosyl protein lyase. Purification, properties, and identification of the product.

1984 • 123 citations

Double Minute Chromosomes Can Be Produced from Precursors Derived from a Chromosomal Deletion

1988 • 112 citations

Two distinct mechanisms of transcriptional control operate on c-myc during differentiation of HL60 cells.

1988 • 106 citations

Autonomously replicating episomes contain mdr1 genes in a multidrug-resistant human cell line.

1989 • 96 citations

Novel submicroscopic extrachromosomal elements containing amplified genes in human cells

1987 • 85 citations

Modulation of C-myc expression in the HL-60 cell line

1984 • 74 citations

Prevention of tumorigenesis of oncogene-transformed rat fibroblasts with DNA site inhibitors of poly(ADP ribose) polymerase.

1987 • 56 citations

Molecular cloning of cDNA for human poly(ADP-ribose) polymerase and expression of its gene during HL-60 cell differentiation

1987 • 54 citations

Deletion of transfected oncogenes from NIH 3T3 transformants by inhibitors of poly(ADP-ribose) polymerase.

1988 • 52 citations

Involvement of poly(ADP-ribose) metabolism in induction of differentiation of HL-60 promyelocytic leukemia cells

1982 • 50 citations

Accumulation of 10-kilobase DNA replication intermediates in cells treated with 3-aminobenzamide.

1985 • 47 citations

Amplification of the c-myc Oncogene is associated with an abnormally banded region on chromosome 8 or double minute chromosomes in two HL-60 human leukemia sublines

1987 • 33 citations

Autonomously Replicating Episomes Contain mdr1 Genes in a Multidrug-Resistant Human Cell Line

1989 • 29 citations

Changes observed in the growth fraction, labeling index, duration of S phase, and total cell cycle times of HL-60 cells as they undergo differentiation in response to retinoic acid.

1988 • 22 citations

c-myc gene inactivation during induced maturation of HL-60 cells. Transcriptional repression and loss of a specific DNAse I hypersensitive site.

1987 • 22 citations