Isolation and characterization of the chickenbcl–2gene: expression in a variety of tissues including lymphoid and neuronal organs in adult and embryo

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

A new method for sequencing DNA.

1977 • 7,941 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1988 • 3,194 citations

Cell Death During Development of the Nervous System

1991 • 3,033 citations

Lambda replacement vectors carrying polylinker sequences

1983 • 1,809 citations

Involvement of the bcl -2 Gene in Human Follicular Lymphoma

1985 • 1,797 citations

Trophic factors and neuronal survival

1989 • 1,631 citations

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.

1991 • 1,301 citations

Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation

1986 • 1,232 citations

Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around Jh on chromosome 14 and near a transcriptional unit on 18

1985 • 1,188 citations

Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma.

1986 • 1,118 citations

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

1991 • 1,090 citations

Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18.

1985 • 972 citations

Splicing of Messenger RNA Precursors

1987 • 919 citations

Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)

1991 • 876 citations

A hyperconversion mechanism generates the chicken light chain preimmune repertoire

1987 • 693 citations

Expression of the bcl-2 oncogene protein is not specific for the 14;18 chromosomal translocation.

1990 • 622 citations

Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma.

1988 • 499 citations

Cloning and sequencing of a deoxyribonucleic acid copy of glyceraldehyde 3-phosphate dehydrogenase messenger ribonucleic acid isolated from chicken muscle

1983 • 486 citations

Germinal center cells express bcl‐2 protein after activation by signals which prevent their entry into apoptosis

1991 • 446 citations

Intron sequences involved in lariat formation during pre-mRNA splicing

1985 • 402 citations

Deregulated Bcl-2-immunoglobulin transgene expands a resting but responsive immunoglobulin M and D-expressing B-cell population.

1990 • 223 citations

Molecular analysis of mbcl-2: Structure and expression of the murine gene homologous to the human gene involved in follicular lymphoma

1987 • 200 citations

Bursal and postbursal stem cells in chicken. functional characteristics

1973 • 197 citations

Characterization of the protein product of bcl-2, the gene involved in human follicular lymphoma.

1987 • 191 citations

Origin of hemopoietic stem cells in embryonic bursa of Fabricius and bone marrow studied through interspecific chimeras.

1975 • 168 citations

Induction of apoptosis during normal and neoplastic B-cell development in the bursa of Fabricius.

1991 • 153 citations

Overexpression of the human BCL-2 gene product results in growth enhancement of Epstein-Barr virus-immortalized B cells.

1989 • 131 citations

Deregulated Bcl-2-Immunoglobulin Transgene Expands a Resting but Responsive Immunoglobulin M and D-Expressing B-Cell Population

1990 • 54 citations

Bursectomy in ovo Blocks the Generation of Immunoglobulin Diversity

1978 • 53 citations

Defect in the generation of light-chain diversity in bursectomized chickens

1984 • 48 citations

Sequential recruitment of antibody class‐committed B lymphocytes during ontogeny

1973 • 22 citations