Characteristics of the cytotoxic effects of the phenothiazine class of calmodulin antagonists

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors.

1982 • 667 citations

Structural similarities between the Ca2+-dependent regulatory proteins of 3':5'-cyclic nucleotide phosphodiesterase and actomyosin ATPase.

1976 • 517 citations

Inhibitory action of chlorpromazine, dibucaine, and other phospholipid-interacting drugs on calcium-activated, phospholipid-dependent protein kinase.

1980 • 464 citations

Calmodulin and the cell cycle: Involvement in regulation of cell-cycle progression

1982 • 414 citations

PHARMACOLOGICAL REGULATION OF CALMODULIN*

1980 • 341 citations

Phospholipid-sensitive Ca2+-dependent protein kinase from heart. II. Substrate specificity and inhibition by various agents.

1982 • 290 citations

Inhibition of calmodulin by phenothiazines and related drugs: structure-activity relationships.

1982 • 259 citations

Changes in calmodulin and its mrna accompany reentry of quiescent (G0) cells into the cell cycle

1984 • 229 citations

Calcium and cell function

1983 • 207 citations

Enhancement of sensitivity to adriamycin in resistant P388 leukemia by the calmodulin inhibitor trifluoperazine.

1983 • 167 citations

Calmodulin stimulates DNA synthesis by rat liver cells

1980 • 164 citations

Calmodulin and cell proliferation

1982 • 134 citations

Potentiation of Bleomycin Lethality by Anticalmodulin Drugs: A Role for Calmodulin in DNA Repair

1984 • 97 citations

Inhibition of growth of leukemic cells by inhibitors of calmodulin: Phenothiazines and melittin

1985 • 83 citations

Occurrence of a low-molecular-weight calcium-binding protein in neoplastic liver.

1979 • 74 citations

Inhibition of human breast cancer colony formation by anticalmodulin agents: Trifluoperazine, W-7, and W-13

1983 • 70 citations

Inhibition of growth of C6 astrocytoma cells by inhibitors of calmodulin

1985 • 66 citations

Mechanism of synergistic cell killing when methotrexate precedes cytosine arabinoside: study of L1210 and human leukemic cells.

1979 • 57 citations

Antitumor effect of a calmodulin antagonist on the growth of solid Sarcoma-180

1983 • 45 citations

The stimulation of cyclic nucleotide phosphodiesterase by A M_r 11 500 calcium binding protein from hepatoma

1981 • 43 citations

Phenothiazines cause a shift in the cAMP dose-response: Selection of resistant variants in a murine thymoma line

1984 • 19 citations