Inhibition of growth of leukemic cells by inhibitors of calmodulin: Phenothiazines and melittin

Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors.

1982 • 667 citations

Structural similarities between the Ca2+-dependent regulatory proteins of 3':5'-cyclic nucleotide phosphodiesterase and actomyosin ATPase.

1976 • 517 citations

Calmodulin and the cell cycle: Involvement in regulation of cell-cycle progression

1982 • 414 citations

Mechanism by which psychotropic drugs inhibit adenosine cyclic 3',5'-monophosphate phosphodiesterase of brain.

1976 • 389 citations

Inhibition of calmodulin by phenothiazines and related drugs: structure-activity relationships.

1982 • 259 citations

Ca2+-dependent regulator. Production and characterization of a monospecific antibody.

1978 • 174 citations

Enhancement of sensitivity to adriamycin in resistant P388 leukemia by the calmodulin inhibitor trifluoperazine.

1983 • 167 citations

Calmodulin stimulates DNA synthesis by rat liver cells

1980 • 164 citations

Regulation of intracellular levels of calmodulin and tubulin in normal and transformed cells.

1981 • 158 citations

Separation of multiple molecular forms of cyclic adenosine-3′,5′-monophosphate phosphodiesterase in rat cerebellum by polyacrylamide gel electrophoresis

1972 • 156 citations

Calmodulin: an overview.

1982 • 133 citations

Calcium-dependent regulatory protein of cyclic nucleotide metabolism in normal and transformed chicken embryo fibroblasts.

1976 • 119 citations

Damage of cellular functions by trifluoperazine, a calmodulin-specific drug

1980 • 111 citations

Potentiation of Bleomycin Lethality by Anticalmodulin Drugs: A Role for Calmodulin in DNA Repair

1984 • 97 citations

Specific visualization of the distribution of the calcium dependent regulatory protein of cyclic nucleotide phosphodiesterase (modulator protein) in tissue culture cells by immunofluorescence microscopy: mitosis and intercellular bridge.

1978 • 92 citations

An increase in calmodulin during growth of normal and cancerous liver in vivo

1981 • 82 citations

Positive correlation between calmodulin content and hepatoma growth rates.

1982 • 81 citations

Mechanisms and Pharmacological Implications of Altering Calmodulin Activity

1980 • 77 citations

Occurrence of a low-molecular-weight calcium-binding protein in neoplastic liver.

1979 • 74 citations

Cations and calmodulin in normal and neoplastic cell growth regulation

1983 • 74 citations

Inhibition of human breast cancer colony formation by anticalmodulin agents: Trifluoperazine, W-7, and W-13

1983 • 70 citations

Inhibition of growth of C6 astrocytoma cells by inhibitors of calmodulin

1985 • 66 citations

Ultrastructural immunocytochemical localization of calmodulin in cultured cells.

1983 • 64 citations

Mechanism of synergistic cell killing when methotrexate precedes cytosine arabinoside: study of L1210 and human leukemic cells.

1979 • 57 citations

Antitumor effect of a calmodulin antagonist on the growth of solid Sarcoma-180

1983 • 45 citations

The stimulation of cyclic nucleotide phosphodiesterase by A M_r 11 500 calcium binding protein from hepatoma

1981 • 43 citations

Occurrence of the tumor-specific, calcium-binding protein, oncomodulin, in virally transformed normal rat kidney cells.

1983 • 33 citations

Characteristics of the cyclic nucleotide phosphodiesterases of normal and leukemic lymphocytes

1977 • 29 citations

Inhibition by calmodulin antagonists of glioblast DNA synthesis and morphological changes induced by glia maturation factor

1982 • 21 citations

Mechanism of synergistic cell killing when methotrexate precedes cytosine arabinoside.

1979 • 21 citations

Interaction of various peptides with calmodulin.

1984 • 11 citations

Inhibition of growth of l1210 leukemic cells by inhibitors of cyclic nucleotide phosphodiesterase (pde) and calmodulin (cal). Abstr.

1983 • 9 citations

Multiple Roles for Calmodulin in the Regulation of Eukaryotic Cell Metabolism

1982 • 6 citations

Cyclic Nucleotide Phosphodiesterase and Protein Activator in Human Cancer Cell Lines and Brown-Pearce Carcinoma

1977 • 6 citations

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