Phenothiazines cause a shift in the cAMP dose-response: Selection of resistant variants in a murine thymoma line

Calmodulin Plays a Pivotal Role in Cellular Regulation

1980 • 2,441 citations

Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids.

1979 • 1,139 citations

Calmodulin

1980 • 982 citations

Calmodulin—an intracellular calcium receptor

1980 • 964 citations

Relationships between calcium and cyclic nucleotides in cell activation.

1977 • 849 citations

Calcium-dependent protein kinase: widespread occurrence in various tissues and phyla of the animal kingdom and comparison of effects of phospholipid, calmodulin, and trifluoperazine.

1980 • 568 citations

Binding of trifluoperazine to the calcium-dependent activator of cyclic nucleotide phosphodiesterase.

1977 • 544 citations

Modulator protein as a component of the myosin light chain kinase from chicken gizzard

1978 • 488 citations

Inhibitory action of chlorpromazine, dibucaine, and other phospholipid-interacting drugs on calcium-activated, phospholipid-dependent protein kinase.

1980 • 464 citations

The interaction of cyclic nucleotides and calcium in the control of cellular activity.

1975 • 451 citations

Calmodulin and the cell cycle: Involvement in regulation of cell-cycle progression

1982 • 414 citations

Mechanism by which psychotropic drugs inhibit adenosine cyclic 3',5'-monophosphate phosphodiesterase of brain.

1976 • 389 citations

Phosphorylation of smooth muscle myosin light chain kinase by the catalytic subunit of adenosine 3‘: 5‘-monophosphate-dependent protein kinase.

1978 • 386 citations

Calmodulin stimulates human platelet phospholipase A2

1979 • 309 citations

Mutations causing charge alterations in regulatory subunits of the cAMP-dependent protein kinase of cultured S49 lymphoma cells

1977 • 222 citations

Anti-schizophrenic drugs—Membrane receptor sites of action

1977 • 221 citations

Differentiated functions expressed by cultured mouse lymphoma cells. II. Theta antigen, surface immunoglobulin and a receptor for antibody on cells of a thymoma cell line.

1973 • 184 citations

Induction of Cytolysis of Cultured Lymphoma Cells by Adenosine 3′:5′-Cyclic Monophosphate and the Isolation of Resistant Variants

1973 • 176 citations

Calcium-dependent adenylate cyclase from rat cerebral cortex. Reversible activation by sodium fluoride.

1977 • 176 citations

Diploid and haploid states of the glucocorticoid receptor gene of mouse lymphoid cell lines

1977 • 170 citations

Interaction of calmodulin with myosin light chain kinase and cAMP-dependent protein kinase in bovine brain.

1981 • 137 citations

Calcium and Cell Function

1982 • 134 citations

Inhibition of smooth muscle tension by cyclic AMP-dependent protein kinase

1981 • 123 citations

Differentiated Functions Expressed by Cultured Mouse Lymphoma Cells

1973 • 117 citations

Protein phosphorylation

1982 • 104 citations

Properties and functions of calmodulin

1981 • 101 citations

Kinase-negative mutants of S49 mouse lymphoma cells carry a trans-dominant mutation affecting expression of cAMP-dependent protein kinase

1978 • 99 citations

Two-dimensional gel analysis of cyclic amp effects in cultured s49 mouse lymphoma cells: Protein modifications, inductions and repressions

1979 • 95 citations

Mutagenesis in S49 mouse lymphoma cells: induction of resistance to ouabain, 6-thioguanine, and dibutyryl cyclic AMP.

1977 • 90 citations

Ca2+ regulated modulator protein interacting agents: Inhibition of Ca2+Mg2+-ATPase of human erythrocyte ghost

1979 • 79 citations

Inhibition by phenothiazine antipsychotic drugs of calcium-dependent phosphorylation of cerebral cortex proteins regulated by phospholipid or calmodulin

1981 • 74 citations

Glucorticoid resistance in murine lymphoma and thymoma lines.

1978 • 62 citations

A structural gene mutation affecting the regulatory subunit of cyclic AMP-dependent protein kinase in mouse lymphoma cells.

1975 • 62 citations

Inhibition by trifluoperazine of calmodulin-induced activation of ATPase activity of rat erythrocyte

1980 • 61 citations

Molecular Mechanisms of Cyclic AMP Action: A Genetic Approach

1976 • 57 citations

Cyclic amp-induced cytolysis in S49 cells: selection of an unresponsive “deathless” mutant

1977 • 53 citations

Inhibition of Ca2+-activated tension and myosin light chain phosphorylation in skinned smooth muscle strips by the phenothiazines

1980 • 48 citations

Isolation and characterization of S49 lymphoma cells deficient in beta-adrenergic receptors: relation of receptor number to activation of adenylate cyclase.

1979 • 37 citations

The Messenger Function of Calcium in Endocrine Systems

1981 • 35 citations

Structure, Function, and Evolution of Calmodulin

1980 • 25 citations

Coexpression of mutant and wild type protein kinase in lymphoma cells resistant to dibutyryl cyclic AMP

1977 • 24 citations

Smooth Muscle Myosin Light Chain Kinase

1980 • 22 citations

Acute and chronic effects of psychoactive drugs on adrenergic receptors and calmodulin.

1980 • 21 citations

Induction of glucocorticoid-resistant variants in a murine thymoma line by antitumor drugs.

1981 • 14 citations