Persistent activation of the zeta isoform of protein kinase C in the maintenance of long-term potentiation.

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Deficient Hippocampal Long-Term Potentiation in α-Calcium-Calmodulin Kinase II Mutant Mice

1992 • 1,458 citations

Inhibition of Postsynaptic PKC or CaMKII Blocks Induction But Not Expression of LTP

1989 • 1,335 citations

Intracellular injections of EGTA block induction of hippocampal long-term potentiation

1983 • 1,106 citations

An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation

1989 • 1,015 citations

Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.

1993 • 966 citations

Long-term potentiation in the hippocampus involves activation of N-methyl-D-aspartate receptors

1984 • 905 citations

Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain.

1977 • 865 citations

Regulation of brain Type II Ca2+/calmodulin-dependent protein kinase by autophosphorylation: A Ca2+-triggered molecular switch

1986 • 856 citations

Postsynaptic Calcium Is Sufficient for Potentiation of Hippocampal Synaptic Transmission

1988 • 830 citations

Potentiation of synaptic transmission in the hippocampus by phorbol esters

1986 • 647 citations

Proteolytic activation of calcium-activated, phospholipid-dependent protein kinase by calcium-dependent neutral protease.

1983 • 601 citations

Persistent protein kinase activity underlying long-term potentiation

1988 • 557 citations

Translocation of Protein Kinase C Activity May Mediate Hippocampal Long-Term Potentiation

1986 • 532 citations

Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors

1991 • 520 citations

Protein kinase C zeta subspecies from rat brain: its structure, expression, and properties.

1989 • 508 citations

A phorbol ester receptor/protein kinase, nPKC eta, a new member of the protein kinase C family predominantly expressed in lung and skin.

1990 • 434 citations

Purification and characterization of the zeta isoform of protein kinase C from bovine kidney.

1992 • 283 citations

A molecular mechanism for long-term sensitization in Aplysia

1987 • 234 citations

Autophosphorylation of rat brain Ca2+-activated and phospholipid-dependent protein kinase.

1986 • 183 citations

Persistent protein kinase activation in the maintenance phase of long-term potentiation.

1991 • 166 citations

Expression of four protein kinase C isoforms in rat fibroblasts. Distinct subcellular distribution and regulation by calcium and phorbol esters.

1992 • 160 citations

Postsynaptic protein kinase C essential to induction and maintenance of long-term potentiation in the hippocampal CA1 region.

1992 • 157 citations

Molecular Mechanisms for Memory: Second-Messenger Induced Modifications of Protein Kinases in Nerve Cells

1987 • 156 citations

Stimulation of NMDA receptors induces proteolysis of spectrin in hippocampus

1988 • 147 citations

A simple, rapid, and sensitive method for measuring protein concentration in subcellular membrane fractions prepared by sucrose density ultracentrifugation

1982 • 142 citations

Enhancement of long-term potentiation by cis-unsaturated fatty acid: relation to protein kinase C and phospholipase A2

1987 • 108 citations

Inhibition of protein kinase C blocks two components of LTP persistence, leaving initial potentiation intact

1990 • 107 citations

Development of hippocampal long-term potentiation is reduced by recently introduced calpain inhibitors

1990 • 102 citations

Inhibition of the proteolysis of rat erythrocyte membrane proteins by a synthetic inhibitor of calpain

1988 • 99 citations

Different translocation of three distinct PKC isoforms with tumor-promoting phorbol ester in human platelets

1991 • 76 citations

Phorbol ester-induced synaptic facilitation is different than long-term potentiation.

1988 • 72 citations

Constitutive presence of a catalytic fragment of protein kinase C epsilon in a small cell lung carcinoma cell line.

1992 • 59 citations