Autophosphorylation of rat brain Ca2+-activated and phospholipid-dependent protein kinase.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover.

1980 • 1,317 citations

Phorbol diester receptor copurifies with protein kinase C.

1983 • 1,185 citations

[42] Detection and quantification of phosphotyrosine in proteins

1983 • 1,184 citations

Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids.

1979 • 1,139 citations

Insulin Stimulates the Phosphorylation of the 95,000-Dalton Subunit of Its Own Receptor

1982 • 1,138 citations

Enzyme changes in neonatal skeletal muscle: effect of thyroid deficiency

1978 • 1,103 citations

Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties.

1982 • 1,008 citations

Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain.

1977 • 865 citations

Unsaturated diacylglycerol as a possible messenger for the activation of calcium-activated, phospholipid-dependent protein kinase system

1979 • 727 citations

Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation.

1983 • 705 citations

Computer calculation of equilibrium concentrations in mixtures of metal ions and complexing species

1967 • 642 citations

Proteolytic activation of calcium-activated, phospholipid-dependent protein kinase by calcium-dependent neutral protease.

1983 • 601 citations

Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. I. Purification and characterization of an active enzyme from bovine cerebellum.

1977 • 587 citations

Calcium-dependent protein kinase: widespread occurrence in various tissues and phyla of the animal kingdom and comparison of effects of phospholipid, calmodulin, and trifluoperazine.

1980 • 568 citations

Phosphorylation activates the insulin receptor tyrosine protein kinase.

1983 • 558 citations

Rapid enhancement of protein phosphorylation in A-431 cell membrane preparations by epidermal growth factor.

1979 • 530 citations

Activation of protein kinase C by Triton X-100 mixed micelles containing diacylglycerol and phosphatidylserine.

1985 • 471 citations

Etudes de dynamique chimique

1884 • 439 citations

Exogenous sn-1,2-diacylglycerols containing saturated fatty acids function as bioregulators of protein kinase C in human platelets.

1985 • 308 citations

Tyrosine phosphorylation of the insulin receptor beta subunit activates the receptor-associated tyrosine kinase activity.

1984 • 299 citations

Platelet-derived growth factor stimulates tyrosine-specific protein kinase activity in Swiss mouse 3T3 cell membranes.

1982 • 293 citations

Characterization of a specific phorbol ester aporeceptor in mouse brain cytosol.

1983 • 292 citations

Phorbol esters stimulate the phosphorylation of receptors for insulin and somatomedin C.

1983 • 291 citations

Purification to homogeneity of protein kinase C from bovine brain-identity with the phorbol ester receptor.

1984 • 283 citations

Inositol phospholipids in membrane function

1979 • 272 citations

Diacylglycerols mimic phorbol diester induction of leukemic cell differentiation.

1985 • 234 citations

Affinity chromatography of protein kinase C-phorbol ester receptor on polyacrylamide-immobilized phosphatidylserine.

1984 • 205 citations

Dissociation and reassociation of the phosphorylated and nonphosphorylated forms of adenosine 3':5' -monophosphate-dependent protein kinase from bovine cardiac muscle.

1976 • 197 citations

Polyclonal antibodies to phospholipid/Ca2+-dependent protein kinase and immunocytochemical localization of the enzyme in rat brain.

1985 • 193 citations

Phosphatidylinositol turnover in platelet activation; Calcium mobilization and protein phosphorylation

1982 • 193 citations

Immunoaffinity purification of the epidermal growth factor receptor. Stoichiometry of binding and kinetics of self-phosphorylation.

1984 • 186 citations

sn-1,2-Dioctanoylglycerol. A cell-permeable diacylglycerol that mimics phorbol diester action on the epidermal growth factor receptor and mitogenesis.

1985 • 179 citations

Purified rat brain calcium- and phospholipid-dependent protein kinase phosphorylates ribosomal protein S6.

1983 • 160 citations

Activation of S6 kinase activity in 3T3-L1 cells by insulin and phorbol ester.

1985 • 155 citations

Mechanism of autophosphorylation of the multifunctional Ca2+/calmodulin-dependent protein kinase.

1985 • 153 citations

A rapid and sensitive assay method for protein kinase

1976 • 121 citations

The insulin receptor protein kinase. Physicochemical requirements for activity.

1983 • 119 citations

A study on the autoactivation of rabbit muscle phosphorylase kinase.

1976 • 103 citations

Role of protein kinase C in diacylglycerol-mediated induction of ornithine decarboxylase and reduction of epidermal growth factor binding.

1985 • 94 citations

Characterization of initial autophosphorylation events in rabbit skeletal muscle phosphorylase kinase.

1983 • 79 citations

Protein kinase C: Rapid enzyme purification and substrate-dependence of the diacylglycerol effect

1984 • 70 citations

Relationship between phosphorylation and activity of heme-regulated eukaryotic initiation factor 2 alpha kinase.

1981 • 62 citations

Control of Enzyme Activity

1983 • 58 citations

Autophosphorylation of phosphorylase kinase. Divalent metal cation and nucleotide dependency.

1983 • 44 citations

Phosphorylation and inactivation of rat liver glycogen synthase by cAMP-dependent protein kinase and cAMP-independent synthase (casein) kinase-1.

1983 • 40 citations