Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo.

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Vascular endothelial cells synthesize nitric oxide from L-arginine

1988 • 4,800 citations

Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo

1990 • 1,869 citations

Role of endothelium-derived nitric oxide in the regulation of blood pressure.

1989 • 1,837 citations

EFFECTS OF ENDOTHELIUM-DERIVED NITRIC OXIDE ON PERIPHERAL ARTERIOLAR TONE IN MAN

1989 • 1,625 citations

L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation

1988 • 1,379 citations

Flow-induced release of endothelium-derived relaxing factor

1986 • 1,379 citations

Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP.

1983 • 949 citations

A specific inhibitor of nitric oxide formation from <scp>l</scp>‐arginine attenuates endothelium‐dependent relaxation

1989 • 862 citations

Endothelium-derived relaxing factor

1988 • 686 citations

Control of regional blood flow by endothelium-derived nitric oxide.

1990 • 447 citations

Depression of contractile responses in rat aorta by spontaneously released endothelium-derived relaxing factor.

1986 • 381 citations

Selective inhibition of cyclic nucleotide phosphodiesterases of human, bovine and rat aorta

1986 • 301 citations

Nitric oxide synthesised from L-arginine mediates endothelium dependent dilatation in human veins in vivo

1989 • 250 citations

Nitric oxide from L-arginine stimulates the soluble guanylate cyclase in adrenal glands

1989 • 238 citations

Postjunctional supersensitivity and subsensitivity of excitable tissues to drugs

1973 • 200 citations

Phosphodiesterase inhibitors induce endothelium-dependent relaxation of rat and rabbit aorta by potentiating the effects of spontaneously released endothelium-derived relaxing factor.

1986 • 167 citations

Enhancement of alpha-1 and alpha-2 adrenergic agonist-induced vasoconstriction by removal of endothelium in rat aorta.

1985 • 163 citations

Desensitization to nitroglycerin in vascular smooth muscle from rat and human

1986 • 153 citations

Effects of Motor Innervation on the Chemical Sensitivity of Skeletal Muscle

1960 • 140 citations

Tolerance towards nitroglycerin, induced in vivo, is correlated to a reduced cGMP response and an alteration in cGMP turnover

1983 • 140 citations

Endothelium removal augments vasodilation by sodium nitroprusside and sodium nitrite

1985 • 127 citations

Biotransformation of glyceryl trinitrate occurs concurrently with relaxation of rabbit aorta.

1986 • 120 citations

Modulation of the Vasodilator Action of SIN-1 by the Endothelium

1989 • 56 citations

Venous and arterial endothelia: different dilator abilities in dog vessels.

1987 • 53 citations

Interaction Between Endothelium-Derived Nitric Oxide and SIN-1 in Human and Porcine Blood Vessels

1989 • 49 citations

Selective inhibition by gossypol of endothelium‐dependent relaxations augments relaxations to glyceryl trinitrate in rabbit coeliac artery

1987 • 43 citations

Mechanism of nitrate-induced vasodilation and tolerance.

1983 • 40 citations

Preparation and characterization of Ng-mono-, di- and trimethylated arginines.

1977 • 34 citations

Biotransformation of Glyceryl Trinitrate and Elevation of Cyclic GMP Precede Glyceryl Trinitrate-Induced Vasodilation

1990 • 30 citations

Mechanisms Underlying the Inhibitory Interaction Between the Nitrovasodilator SIN-1 and the Endothelium

1989 • 23 citations

ANTIMETABOLITES PRODUCED BY MICROORGANISMS. VI 1) L-N5-(1-IMINOETHYL) ORNITHINE

1972 • 23 citations

Über die Bewegung der Iris für Physiologen und Ärzte

1855 • 11 citations

Deleted Work

1955 • 0 citations