Selective inhibition of cyclic nucleotide phosphodiesterases of human, bovine and rat aorta

Role of endothelium in responses of vascular smooth muscle.

1983 • 1,975 citations

The Fluorometric Measurement of Deoxyribonucleic Acid in Animal Tissues with Special Reference to the Central Nervous System

1958 • 1,786 citations

Vascular smooth muscle. I. Normal structure, pathology, biochemistry, and biophysics.

1968 • 887 citations

The Combinations of Haemoglobin with Oxygen and with Carbon Monoxide. I

1913 • 777 citations

Cyclic 3',5'-Nucleotide Phosphodiesterase

1971 • 531 citations

A modified fluorometric method for the determination of microgram quantities of DNA from cell or tissue cultures

1976 • 315 citations

Evidence for cyclic GMP-mediated relaxant effects of nitro-compounds in coronary smooth muscle

1979 • 301 citations

Adenosine 3′,5′ cyclic monophosphate assay at 10−15 mole level

1973 • 262 citations

Guanosine 3' ,5'-Cyclic Monophosphate Assay at 10−15-Mole Level

1976 • 256 citations

Reinvestigation of extremely acidic proteins in bovine brain

1977 • 209 citations

Effects of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle

1984 • 138 citations

Identification and properties of cyclic nucleotide phosphodiesterases

1982 • 135 citations

Selective inhibitor of platelet cyclic adenosine monophosphate phosphodiesterase, cilostamide, inhibits platelet aggregation.

1979 • 102 citations

HL 725, an extremely potent inhibitor of platelet phosphodiesterase and induced platelet aggregation in vitro

1982 • 82 citations

Purification and characterization of cyclic GMP-stimulated cyclic nucleotide phosphodiesterase from calf liver. Effects of divalent cations on activity.

1983 • 80 citations

Cyclic nucleotide phosphodiesterase activities from pig coronary arteries. Lack of interconvertibility of major forms

1980 • 64 citations

Inhibition of separated forms of cyclic nucleotide phosphodiesterase from pig coronary arteries by 1,3-disubstituted and 1,3,8-trisubstituted xanthines

1981 • 55 citations

Trequinsin, a potent new antihypertensive vasodilator in the series of 2-(arylimino)-3-alkyl-9,10-dimethoxy-3,4,6,7-tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-ones

1984 • 50 citations

Tissue and substrate specificity of inhibition by alkoxy-aryl-lactams of platelet and arterial smooth muscle cyclic nucleotide phosphodiesterases relationship to pharmacological activity

1983 • 49 citations

Identification of cGMP-stimulated cyclic nucleotide phosphodiesterase in lung tissue with monoclonal antibodies.

1982 • 48 citations

Effect of vasoactive intestinal polypeptide (VIP) on cyclic AMP level and relaxation in rat isolated aorta

1985 • 43 citations

New trends in arterial hypertension

1982 • 36 citations

Age-related decrease of in vitro isoproterenol-induced cyclic AMP accumulation in rat aorta

1982 • 35 citations

Vascular Smooth Muscle

2016 • 29 citations

Effect of papaverine on cyclic nucleotide levels in the isolated rat aorta

1977 • 24 citations

Differences in the association of calmodulin with cyclic nucleotide phosphodiesterase in relaxed and contracted arterial strips

1985 • 22 citations

Substituted carbostyrils as inhibitors of cyclic AMP phosphodiesterase

1985 • 18 citations

Separation of three cyclic-nucleotide-phosphodiesterases from bovine aorta

1978 • 17 citations

Chromatographic behavior of cyclic 3',5'-nucleotide phosphodiesterases on columns of immobilized inhibitors

1978 • 13 citations