Modulation of afferent‐evoked neurotransmission by 5‐HT₃ receptors in young rat dorsal horn neurones in vitro: a putative mechanism of 5‐HT₃ induced anti‐nociception

EVIDENCE FOR THE EXISTENCE OF MONOAMINE-CONTAINING NEURONS IN THE CENTRAL NERVOUS SYSTEM. I. DEMONSTRATION OF MONOAMINES IN THE CELL BODIES OF BRAIN STEM NEURONS.

1964 • 5,110 citations

International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin).

1994 • 2,935 citations

Distribution of serotonin-immunoreactivity in the central nervous system of the rat—Cell bodies and terminals

1981 • 2,392 citations

5-HT3 receptors are membrane ion channels

1989 • 630 citations

Central inhibitory action attributable to presynaptic depolarization produced by muscle afferent volleys

1961 • 405 citations

Activity‐Dependent Changes in Rat Ventral Horn Neurons in vitro; Summation of Prolonged Afferent Evoked Postsynaptic Depolarizations Produce a D‐2‐Amino‐5‐Phosphonovaleric Acid Sensitive Windup

1990 • 270 citations

Spinal 5-HT3 receptor-mediated antinociception: possible release of GABA

1991 • 259 citations

5-HT3 receptor binding sites are on capsaicin-sensitive fibres in the rat spinal cord

1989 • 184 citations

International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. IX. Recommendations on terms and symbols in quantitative pharmacology.

1995 • 162 citations

5-HT3 receptors in the rat central nervous system are mainly located on nerve fibres and terminals

1993 • 162 citations

Monoamine release from cat spinal cord by somatic stimuli: an intrinsic modulatory system.

1981 • 160 citations

Immunocytochemical analysis of serotonergic axons in laminae I and II of the lumbar spinal cord of the cat

1982 • 158 citations

Raphe magnus stimulation-induced antinociception in the cat is associated with release of amino acids as well as serotonin in the lumbar dorsal horn

1993 • 136 citations

Long‐lasting synaptic facilitation induced by serotonin in superficial dorsal horn neurones of the rat spinal cord.

1996 • 135 citations

5-HT3 receptors modulate spinal nociceptive reflexes

1990 • 132 citations

Dual effect of serotonin on formalin-induced nociception in the rat spinal cord

1996 • 129 citations

Reversal of the antinociceptive effects of intrathecally administered serotonin in the rat by a selective 5-HT3 receptor antagonist

1988 • 126 citations

Do dorsal root reflexes augment peripheral inflammation?

1994 • 117 citations

The role of 5HT3 in nociceptive processing in the rat spinal cord: results from behavioural and electrophysiological studies

1996 • 112 citations

Evidence that spinal 5-HT1, 5-HT2 and 5-HT3 receptor subtypes modulate responses to noxious colorectal distension in the rat

1991 • 111 citations

5-Hydroxytryptamine and antinociception

1984 • 110 citations

Serotonin receptor subtypes in spinal antinociception in the rat.

1994 • 107 citations

Differential roles of 5-hydroxytryptamine1A and 5-hydroxytryptamine1B receptor subtypes in modulating spinal nociceptive transmission in mice.

1993 • 101 citations

Localization of 5-HT3 receptors in the rat spinal cord

1995 • 101 citations

An electron microscope study of glycine-like immunoreactivity in laminae I–III of the spinal dorsal horn of the rat

1990 • 100 citations

The role of 5-HT3 receptors in periaqueductal gray-induced inhibition of nociceptive dorsal horn neurons in rats.

1996 • 99 citations

Heterogenous effects of serotonin in the dorsal horn of rat: the involvement of 5-HT1 receptor subtypes

1988 • 97 citations

Analgesic effects of serotonin and receptor-selective serotonin agonists in the rat spinal cord

1991 • 96 citations

The actions of 5-HT1 agonists and antagonists on nociceptive processing in the rat spinal cord: results from behavioural and electrophysiological studies

1994 • 73 citations

Effects of dorsal rhizotomy and selective lesion of serotonergic and noradrenergic systems on 5-HT1a , 5-HT1b and 5-HT3 receptors in the rat spinal cord

1995 • 65 citations

Receptive fields and responses to ionophoretically applied nonradrenaline and 5-hydroxytryptamine of units recorded in laminae I–III of cat dorsal horn

1983 • 63 citations

Analgesic profile of centrally administered 2-methylserotonin against acute pain in rats

1991 • 62 citations

Mechanisms of allodynia

1996 • 60 citations

5-HT<sub>1A</sub> Receptors Mediate the Effect of the Bulbospinal Serotonin System on Spinal Dorsal Horn Nociceptive Neurons

1994 • 55 citations

Pharmacological Studies of Grooming and Scratching Behavior Elicited by Spinal Substance P and Excitatory Amino Acidsa

1988 • 55 citations

Autoradiographic mapping of serotonin 5-HT1A, 5-HT1D, 5-HT2A and 5-HT3 receptors in the aged human spinal cord

1996 • 53 citations

5-Hydroxytryptamine reduces substabce P responses on dorsal horn interneurones: a possible interaction of neurotransmitters

1981 • 52 citations

Properties of 5‐hydroxytryptamine₃ receptor‐gated currents in adult rat dorsal root ganglion neurones

1991 • 47 citations

Pre‐ and Post‐synaptic Actions of 5‐Hydroxytryptamine in the Rat Lumbar Dorsal Horn In Vitro: Implications for Somatosensory Transmission

1996 • 44 citations

Differential influence of two serotonin 5-HT3 receptor antagonists on spinal serotonin-induced analgesia in rats

1997 • 40 citations

Contacts between serotoninergic fibres and dorsal horn spinocerebellar tract neurons in the cat and rat: A confocal microscopic study

1995 • 31 citations

Serotonergic modulation of the responses to excitatory amino acids of rat dorsal horn neurons in vitro: implications for somatosensory transmission

1998 • 28 citations

Nociceptive and antinociceptive action of serotonergic agonists administered intrathecally

1990 • 25 citations

Spinal serotonin IA and IC/2 receptors mediate supraspinal μ opioidinduced analgesia

1994 • 22 citations

Antinociceptive effects of intrathecally administered 2-methylserotonin in developing rats

1997 • 20 citations

An in vitro study of the effects of serotonin on frog primary afferent terminals

1990 • 19 citations

Attenuation of defensive analgesia in male mice by 5-HT3 receptor antagonists, ICS 205-930, MDL 72222, MDL 73147EF and MDL 72699

1992 • 18 citations

A novel methodology for simultaneous assessment of the effects of 5-hydroxytryptamine on primary afferent polarisation and synaptic transmission in rat dorsal horn neurones in vitro

1996 • 14 citations

Serotonin-induced population primary afferent depolarisation in vitro: the effects of neonatal capsaicin treatment

1998 • 13 citations

Blockade of 5‐HT₃ receptor‐mediated currents in dissociated frog sensory neurones by benzoxazine derivative, Y‐25130

1992 • 13 citations

Modulation of frog spinal cord interneuronal activity by activation of 5-HT3 receptors

1995 • 10 citations

Role of Aδ afferent fibers in modulation of primary afferent input to the adult rat spinal cord

1995 • 8 citations

The pharmacology of dorsal root potentials recorded from the isolated spinal cord of the neonate rat

1980 • 5 citations