Heterogenous effects of serotonin in the dorsal horn of rat: the involvement of 5-HT1 receptor subtypes

Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors

1985 • 1,855 citations

Diffuse noxious inhibitory controls (DNIC). I. Effects on dorsal horn convergent neurones in the rat

1979 • 1,325 citations

Multiple serotonin receptors: differential binding of [3H]5-hydroxytryptamine, [3H]lysergic acid diethylamide and [3H]spiroperidol.

1979 • 1,321 citations

Proposals for the classification and nomenclature of functional receptors for 5-hydroxytryptamine

1986 • 1,255 citations

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

1982 • 1,049 citations

EVIDENCE FOR THE EXISTENCE OF MONOAMINE NEURONS IN THE CENTRAL NERVOUS SYSTEM. II. EXPERIMENTALLY INDUCED CHANGES IN THE INTRANEURONAL AMINE LEVELS OF BULBOSPINAL NEURON SYSTEMS.

1965 • 1,004 citations

8-Hydroxy-2-(di-n-propylamino)-tetralin discriminates between subtypes of the 5-HT1 recognition site

1983 • 869 citations

TWO KINDS OF TRYPTAMINE RECEPTOR

1957 • 838 citations

Quantitative autoradiographic mapping of serotonin receptors in the rat brain. II. Serotonin-2 receptors

1985 • 803 citations

Diffuse noxious inhibitory controls (DNIC). II. Lack of effect on non-convergent neurones, supraspinal involvement and theoretical implications

1979 • 765 citations

Identification of presynaptic serotonin autoreceptors using a new ligand: 3H-PAT

1983 • 759 citations

Discrimination of Multiple [³H]5‐Hydroxytryptamine Binding Sites by the Neuroleptic Spiperone in Rat Brain

1981 • 629 citations

The binding of serotonergic ligands to the porcine choroid plexus: Characterization of a new type of serotonin recognition site

1984 • 598 citations

Molecular pharmacology of 5-HT1 and 5-HT2 recognition sites in rat and pig brain membranes: Radioligand binding studies with [3H]5-HT, [3H]8-OH-DPAT, (−)[125I]iodocyanopindolol, [3H]mesulergine and [3H]Ketanserin

1985 • 581 citations

8-hydroxy-2-(di-n-propylamino)tetralin, 8-OH-DPAT, a potent and selective simplified ergot congener with central 5-HT-receptor stimulating activity

1982 • 517 citations

Spinal serotonin terminal system mediates antinociception

1981 • 504 citations

[³H]8‐Hydroxy‐2‐(Di‐n‐Propylamino)Tetralin Binding to Pre‐ and Postsynaptic 5‐Hydroxytryptamine Sites in Various Regions of the Rat Brain

1985 • 458 citations

Neurotransmitters decrease the calcium component of sensory neurone action potentials

1978 • 409 citations

Characterization of a novel 3H-5-hydroxytryptamine binding site subtype in bovine brain membranes

1987 • 406 citations

Pharmacological Differentiation and Characterization of 5‐HT_1A, 5‐HT_1B, and 5‐HT_1C Binding Sites in Rat Frontal Cortex

1986 • 344 citations

The differential effects of 5-hydroxytryptamine, noradrenaline and raphe stimulation on nociceptive and non-nociceptive dorsal horn interneurones in the cat

1978 • 334 citations

Selective reduction by noradrenaline and 5-hydroxytryptamine of nociceptive responses of cat dorsal horn neurones

1978 • 332 citations

Determination of selective and nonselective compounds for the 5-HT 1A and 5-HT 1B receptor subtypes in rat frontal cortex.

1984 • 324 citations

Origins of serotonergic projections to the spinal cord in rat: An immunocytochemical-retrograde transport study

1981 • 314 citations

Characterization of the 5-HTIB recognition site in rat brain: Binding studies with (−)[125I]Iodocyanopindolol

1985 • 281 citations

Inhibition of spinothalamic tract cells and interneurons by brain stem stimulation in the monkey

1977 • 276 citations

Descending inhibitory influences from periaqueductal gray, nucleus raphe magnus, and adjacent reticular formation. II. Effects on medullary dorsal horn nociceptive and nonnociceptive neurons

1983 • 205 citations

Organization of Descending Serotonergic Projections to the Spinal Cord

1982 • 189 citations

The topographical distribution of serotoninergic terminals in the spinal cord of the cat: biochemical mapping by the combined use of microdissection and microassay procedures

1977 • 178 citations

Two distinct serotonin receptors: regional variations in receptor binding in mammalian brain

1981 • 176 citations

Biochemical and pharmacological characterization of CGS 12066B, a selective serotonin-1B agonist

1987 • 159 citations

Inhibition of the spinal transmission of nociceptive information by supraspinal stimulation in the cat

1979 • 158 citations

Effects induced by stimulation of the centralis inferior nucleus of the raphe on dorsal horn interneurons in cat's spinal cord

1977 • 158 citations

Pharmacological antagonism of the antinociceptive effects of serotonin in the rat spinal cord

1983 • 142 citations

Pharmacological evidence for the involvement of serotonergic mechanisms in diffuse noxious inhibitory controls (DNIC)

1982 • 137 citations

Are there selective ligands for 5-HT1A and 5-HT1B receptor binding sites in brain?

1986 • 136 citations

Serotonin-S2 receptor binding sites and functional correlates

1984 • 130 citations

The effects of focal stimulation in nucleus raphe magnus and periaqueductal gray on intracellularly recorded neurons in spinal laminae I and II

1986 • 129 citations

Depression of primate spinothalamic tract neurons by iontophoretic application of 5-hydroxytryptamine

1978 • 126 citations

Effects of 5-hydroxytryptamine and bradykinin in cat dorsal horn neurones activated by noxious stimuli

1976 • 124 citations

Effects of stimulating in raphe nuclei and in reticular formation on response of spinothalamic neurons to mechanical stimuli

1979 • 124 citations

Descending inhibitory influences from periaqueductal gray, nucleus raphe magnus, and adjacent reticular formation. I. Effects on lumbar spinal cord nociceptive and nonnociceptive neurons

1983 • 122 citations

Nucleus raphe magnus modulation of response of rat dorsal horn neurons to unmyelinated fiber inputs: partial involvement of serotonergic pathways

1980 • 117 citations

Fine structure of serotonin-containing axons in the marginal zone of the rat spinal cord

1983 • 116 citations

Serotoninergic axonal contacts on identified cat spinal dorsal horn neurons and their correlation with nucleus raphe magnus stimulation

1984 • 109 citations

The putative 5-HT1 receptor agonist, RU 24969, inhibits the efflux of 5-hydroxytryptamine from rat frontal cortex slices by stimulation of the 5-HT autoreceptor

1985 • 104 citations

The effects of serotonin antagonists on the inhibition of primate spinothalamic tract cells produced by stimulation in nucleus raphe magnus or periaqueductal gray.

1982 • 103 citations

Inhibition of nociceptive and nonnociceptive responses of primate spinothalamic cells by stimulation in medial brain stem.

1981 • 101 citations

Species variations in RU 24969 interactions with non-5-HT1A binding sites

1986 • 98 citations

Postsynaptic inhibition of primate spinothalamic neurons by stimulation in nucleus raphe magnus

1981 • 95 citations

Blockade of the central 5-HT autoreceptor by β-adrenoceptor antagonists

1986 • 90 citations

Increase of serotonin metabolism within the dorsal horn of the spinal cord during nucleus raphe magnus stimulation, as revealed by in vivo electrochemical detection

1982 • 85 citations

Biochemical assessment of the central 5-HT agonist activity of RU 24969 (a piperidinyl indole)

1980 • 85 citations

Diffuse noxious inhibitory controls (DNIC) in the rat with or without pCPA pretreatment

1981 • 71 citations

The topographical distribution of serotoninergic terminals in the spinal cord of the cat: Quantitative radioautographic studies

1978 • 60 citations

Serotonin innervation of physiologically identified lamina I projection neurons

1986 • 60 citations

Effect of iontophoretically applied 5-hydroxytryptamine on the excitability of single primary afferent C- and A-fibers in the cat spinal cord

1981 • 57 citations

Structure-activity relationships and mechanism of action of hallucinogenic agents based on drug discrimination and radioligand binding studies.

1986 • 55 citations

Immunocytochemical identification of serotonin axonal contacts on characterized neurons in laminae I and II of the cat dorsal horn

1983 • 54 citations

Reduction of the response of cat spinothalamic neurons to graded mechanical stimuli by electrical stimulation of the lower brain stem

1975 • 53 citations

Prolonged depression of spinal transmission of nociceptive information by 5-HT administered in the substantia gelatinosa: antagonism by methysergide

1980 • 52 citations

Serotonin depolarizes type A and C primary afferents: an intracellular study in bullfrog dorsal root ganglion

1985 • 42 citations

Behavioral model for diffuse noxious inhibitory controls (DNIC): potentiation by 5-hydroxytryptophan

1982 • 35 citations

Raphe magnus inhibition of feline T1-T4 spinoreticular tract cell responses to visceral and somatic inputs

1985 • 33 citations

Effects of periaqueductal gray and raphe magnus stimulation on the responses of spinocervical and other ascending projection neurons to non-noxious inputs

1984 • 23 citations

Descending serotonergic fibers in the dorsolateral and ventral funiculi of cat spinal cord

1985 • 21 citations

Substance P, enkephalin and serotonin: Ultrastructural basis of pain transmission in primate spinal cord

1981 • 19 citations

Systematic mapping of descending inhibitory control by the medulla of nociceptive spinal neurones in cats

1983 • 12 citations

Characterization of receptors for 5-hydroxytryptamine in spinal cord

1985 • 12 citations