Introducing a mouse model for pre‐eclampsia: adoptive transfer of activated Th1 cells leads to pre‐eclampsia‐like symptoms exclusively in pregnant mice

Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon?

1993 • 2,828 citations

Preeclampsia: An excessive maternal inflammatory response to pregnancy

1999 • 1,855 citations

Th 1-type immunity is incompatible with successful pregnancy

1997 • 1,008 citations

Preeclampsia is associated with failure of human cytotrophoblasts to mimic a vascular adhesion phenotype. One cause of defective endovascular invasion in this syndrome?

1997 • 920 citations

Synthesis of T helper 2-type cytokines at the maternal-fetal interface.

1993 • 911 citations

Some immunological and endocrinological problems raised by the evolution of viviparity in verte- brates

1953 • 838 citations

Interferon γ Contributes to Initiation of Uterine Vascular Modification, Decidual Integrity, and Uterine Natural Killer Cell Maturation during Normal Murine Pregnancy

2000 • 805 citations

Tryptophan catabolism and T-cell tolerance: immunosuppression by starvation?

1999 • 650 citations

Prevention of T cell–driven complement activation and inflammation by tryptophan catabolism during pregnancy

2001 • 425 citations

IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells.

1995 • 424 citations

Clinical and Biochemical Evidence of Endothelial Cell Dysfunction in the Pregnancy Syndrome Preeclampsia

1991 • 402 citations

A new animal model for human preeclampsia: Ultra-lowdose endotoxin infusion in pregnant rats

1994 • 294 citations

Hypertension Induced in Pregnant Mice by Placental Renin and Maternal Angiotensinogen

1996 • 254 citations

Specialized roles of the chemokine receptors CCR1 and CCR5 in the recruitment of monocytes and TH1-like/CD45RO+T cells

2001 • 253 citations

Increased T‐Helper‐1‐Type Immunity and Decreased T‐Helper‐2‐Type Immunity in Patients with Preeclampsia

1999 • 238 citations

Endotoxemic renal failure in mice: Role of tumor necrosis factor independent of inducible nitric oxide synthase

2001 • 206 citations

Products of activated lymphocytes and macrophages inhibit mouse embryo development in vitro.

1987 • 203 citations

Discovery of a Spontaneous Genetic Mouse Model of Preeclampsia

2002 • 188 citations

Neutrophil activation in pregnancy‐induced hypertension

1989 • 170 citations

Roles of IL-4 and IL-12 in the development of lupus in NZB/W F1 mice.

1997 • 153 citations

Contributions of angiotensin II and tumor necrosis factor-α to the development of renal fibrosis

2001 • 146 citations

Could an infectious trigger explain the differential maternal response to the shared placental pathology of preeclampsia and normotensive intrauterine growth restriction?

2002 • 144 citations

T helper 1- and T helper 2-type cytokine imbalance in pregnant women with pre-eclampsia

1999 • 124 citations

Can murine uterine natural killer cells give insights into the pathogenesis of preeclampsia?

2000 • 123 citations

Maternal and fetal immune responses during pregnancy.

1993 • 107 citations

Activation and injury of endothelial cells by cytokines.

1998 • 89 citations

Pre‐eclampsia and cytokine induced oxidative stress

1993 • 87 citations

Generation and purification of CD8+ melan-A-specific cytotoxic T lymphocytes for adoptive transfer in tumor immunotherapy.

2000 • 85 citations

Effects of Tumor Necrosis Factor‐Alpha on Human Trophoblast Cell Adhesion and Motility

1996 • 79 citations

Murine fetal resorption and experimental pre-eclampsia are induced by both excessive Th1 and Th2 activation

2000 • 68 citations

Cold-induced stress stimulates the sympathetic nervous system, causing hypertension and proteinuria in rats

1997 • 67 citations

Endothelial-derived nitric oxide and angiotensinogen: blood pressure and metabolism during mouse pregnancy

2001 • 61 citations

Attachment and differentiation in vitro of trophoblast from normal and preeclamptic human placentas

1996 • 61 citations

Altered circulating levels of adhesion molecules at 18 weeks’ gestation among women with eventual preeclampsia: Indicators of disturbed placentation in absence of evidence of endothelial dysfunction?

2000 • 56 citations

Upregulation of Decidual P-Selectin Expression Is Associated with an Increased Number of Th1 Cell Populations in Patients Suffering from Spontaneous Abortions

2001 • 55 citations

Anti-CD3 + IL-2-stimulated murine killer cells. In vitro generation and in vivo antitumor activity.

1989 • 51 citations

Increased sensitivity to thromboplastin synthesis in blood monocytes from pre‐eclamptic patients

1985 • 33 citations

Pre-eclampsia and the inflammatory response

2001 • 31 citations

Changes in endogenous cytokines, adhesion molecules and platelets during cytokine-induced tumour necrosis

1995 • 31 citations

HELLP Syndrome-Like Biochemical Parameters Obtained with Endothelin-1 Injections in Rabbits

1993 • 30 citations

Adoptive Transfer of Anti-CD3–Activated CD4+ T Cells Plus Cyclophosphamide and Liposome-Encapsulated Interleukin-2 Cure Murine MC-38 and 3LL Tumors and Establish Tumor-Specific Immunity

1997 • 29 citations

Interest in preeclampsia for researchers in reproduction

2002 • 29 citations

Chemokine receptors and other surface molecules preferentially associated with human Th1 or Th2 cells

1999 • 22 citations

Endotoxemic renal failure in mice: Role of tumor necrosis factor independent of inducible nitric oxide synthase

2001 • 18 citations

Homing of In Vitro-Generated Donor Antigen-Reactive CD4+ T Lymphocytes to Renal Allografts Is α4β1 But Not αLβ2 Integrin Dependent

2001 • 14 citations

Role of Regulatory T Cells in the “Infectious” Tolerance Pathway in Transplant Recipients

1998 • 7 citations

MD41, a novel T helper 0 clone, mediates mast‐cell dependent delayed‐type hypersensitivity in mice

2002 • 5 citations

Adoptive transfer of regulatory T cells following chronic allograft rejection induces tolerance for secondary allografts

2002 • 4 citations

[The effect of inhibition of nitric oxide synthesis on vasoregulatory factors in pregnant rats].

1999 • 3 citations

The Effect of Inhibition of Nitric Oxide Synthesis on Vasoregulatory Factors in Pregnant Rats

1999 • 1 citations