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Adoptive Transfer of Anti-CD3–Activated CD4+ T Cells Plus Cyclophosphamide and Liposome-Encapsulated Interleukin-2 Cure Murine MC-38 and 3LL Tumors and Establish Tumor-Specific Immunity

Data up to Jan 2025

Published1997
Citations29
References27

Total Citations Per Year

Abstract

References (27)

Alterations in Signal Transduction Molecules in T Lymphocytes from Tumor-Bearing Mice

1992 • 650 citations

Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells.

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Loss of T-cell receptor zeta chain and p56lck in T-cells infiltrating human renal cell carcinoma.

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Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma.

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Human CD4+ T cells specifically recognize a shared melanoma-associated antigen encoded by the tyrosinase gene.

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Augmentation of the human immune response by cyclophosphamide.

1982 • 136 citations

Enhanced Metastatic Potential of Tumor Cells Harvested From Spontaneous Metastases of Heterogeneous Murine Tumors<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref><xref ref-type="fn" rid="FN4">4</xref>

1982 • 133 citations

Melanoma‐specific CD4+ T lymphocytes recognize human melanoma antigens processed and presented by epstein‐barr virus‐transformed B cells

1994 • 86 citations

In vivo antitumor activity of anti-CD3-induced activated killer cells.

1989 • 69 citations

Lymphokine-activated killer activity in long-term cultures with anti-CD3 plus interleukin 2: identification and isolation of effector subsets.

1989 • 61 citations

CD4+ T lymphocytes infiltrating human breast cancer recognise autologous tumor in an MHC-class-II restricted fashion

1995 • 59 citations

Cellular interactions in effector cell generation and tumor regression mediated by anti-CD3/interleukin 2-activated tumor-draining lymph node cells.

1992 • 55 citations

Anti-CD3 + IL-2-stimulated murine killer cells. In vitro generation and in vivo antitumor activity.

1989 • 51 citations

Antitumor effects of interleukin 2 liposomes and anti-CD3-stimulated T-cells against murine MCA-38 hepatic metastasis.

1991 • 50 citations

Treatment of cancer patients with ex vivo anti-CD3-activated killer cells and interleukin-2.

1993 • 45 citations

Adoptive chemoimmunotherapy of murine leukemia with helper T lymphocyte clones.

1987 • 39 citations

Detection of melanoma-reactive CD4+ HLA-class I-restricted cytotoxic T cell clones with long-term assay and pretreatment of targets with interferon-?

1993 • 35 citations

Therapeutic and Toxic Activity of Tumor Necrosis Factor Is Synergistic with Gamma Interferon

1989 • 13 citations

An interactive computer program for the analysis of growth curves

1987 • 9 citations

Importance in timing of cyclophosphamide on the enhancement of interleukin-2-induced cytolysis

1991 • 9 citations

VARCOV: A computer program for the distribution-free analysis of growth and response curves

1984 • 8 citations

Anti-CD3+IL-2-stimulated murine killer cells

1989 • 6 citations

CD4+ T lymphocytes infiltrating human breast cancer recognise autologous tumor in an MHC-class-II restricted fashion

1995 • 6 citations

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Adoptive Transfer of Anti-CD3–Activated CD4+ T Cells Plus Cyclophosphamide and… (1997) – Blood | Metascience Observatory Explorer