L3T4 (CD4+) cells that mediate contact sensitivity to trinitrochlorobenzene express I-A determinants

Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB.

1980 • 983 citations

STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS

1935 • 697 citations

Ia determinants on stimulated human T lymphocytes. Occurrence on mitogen- and antigen-activated T cells.

1979 • 443 citations

Contact and delayed hypersensitivity in the mouse. I. Active sensitization and passive transfer.

1968 • 379 citations

Direct demonstration of the clonogenic potential of every human peripheral blood T cell. Clonal analysis of HLA-DR expression and cytolytic activity.

1983 • 351 citations

The role of IFN-gamma in delayed-type hypersensitivity mediated by Th1 clones.

1989 • 304 citations

Leukotriene B: a potential mediator of inflammation

1980 • 303 citations

Cell-mediated immunity: delayed-type hypersensitivity and cytotoxic responses are mediated by different T-cell subclasses.

1976 • 214 citations

Ly and Ia antigen phenotypes of T cells involved in delayed-type hypersensitivity and in suppression.

1976 • 208 citations

Lymphocyte recruitment in delayed-type hypersensitivity. The role of IFN-gamma.

1988 • 170 citations

An Overview of T-Suppressor Cell Circuits

1986 • 148 citations

Delayed-type hypersensitivity: activation of mast cells by antigen-specific T-cell factors initiates the cascade of cellular interactions

1983 • 135 citations

Suppressive Mechanisms Involving Sensitization and Tolerance in Contact Allergy

1980 • 135 citations

IL-1 and IFN-gamma increase vascular permeability.

1988 • 131 citations

T-lymphocyte-enriched murine peritoneal exudate cells. II. Genetic control of antigen-induced T-lymphocyte proliferation.

1976 • 120 citations

Tolerance and Contact Sensitivity to DNFB in Mice

1974 • 112 citations

Tolerance and contact sensitivity to DNFB in mice. 3. Transfer of tolerance with "suppressor T cells".

1974 • 110 citations

Dual Immunological Unresponsiveness Induced by Cell Membrane Coupled Hapten or Antigen*

1966 • 108 citations

Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. VIII. Suppressor cell pathways in cutaneous sensitivity responses.

1981 • 101 citations

Malignant Tumours of Liver and Lung in Rats fed Aminopyrine or Heptamethyleneimine together with Nitrite

1973 • 85 citations

Tolerance and contact sensitivity to DNFA in mice. VIII. Identification of distinct T cell subpopulations that mediate in vivo and in vitro manifestations of delayed hypersensitivity.

1978 • 84 citations

Characterization of two different Ly-1+ T cell populations that mediate delayed-type hypersensitivity.

1984 • 84 citations

Regulation of Cell Mediated Immunity by Antibodies: Possible Role of Anti-Receptor Antibodies in the Regulation of Contact Sensitivity to DNFB in Mice

1979 • 75 citations

The mechanism of immunological unresponsiveness to picryl chloride and the possible role of antibody mediated depression.

1971 • 55 citations

Orally induced tolerance generates an efferently acting suppressor T cell and an acceptor T cell that together down-regulate contact sensitivity.

1985 • 51 citations

The recruitment of lymphocytes into the skin by T cell lymphokines: the role of gamma-interferon.

1988 • 51 citations

Tolerance and Contact Sensitivity to DNFB in Mice

1978 • 50 citations

T cell responses induced by the parenteral injection of antigen-modified syngeneic cells. I. Induction, characterization, and regulation of antigen-specific T helper cells involved in delayed-type hypersensitivity responses.

1983 • 40 citations

Oral administration of the contact sensitizer trinitrochlorobenzene: Initial sensitization and subsequent appearance of a suppressor population

1990 • 35 citations

Contact sensitivity in the mouse. XII. The use of DNA synthesis in vivo to determine the anatomical location of immunological unresponsiveness to picryl chloride.

1973 • 29 citations

Anatomical Location of Cells which mediate Contact Sensitivity in the Lymph Nodes and Bone Marrow

1973 • 29 citations

Structural requirements of immunoglobulin G for binding to the Fc gamma receptors of the human tumor cell lines U937, HL-60, ML-1, and K562.

1985 • 23 citations

Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. VI. Evidence for different T cell receptors in cells that mediate H-21-restricted and H-2D-restricted cutaneous sensitivity responses.

1980 • 19 citations

Nonspecific T suppressor factor (nsTsF) cascade in contact sensitivity: nsTsF-1 causes an Ly-1+2- I-A+ immune T cell to produce a second, genetically restricted, nsTsF-2.

1986 • 19 citations

T helper factor in contact sensitivity: antigen-specific I-A+ helper factor is made by an Lyt-1+2-, I-A+, I-J- T cell.

1984 • 18 citations

The role of t cells in the passive transfer of contact sensitivity and their occurrence in the bone marrow

1973 • 18 citations

Differences in the ability of T cells to suppress the induction and expression of contact sensitivity.

1981 • 17 citations

Two distinct suppressor T cells acting in concert cause suppression of cytolytic T lymphocyte (CTL) response to hapten-altered self in vivo.

1983 • 9 citations

Feeding trinitrochlorobenzene inhibits development of hapten-specific cytotoxic T lymphocytes by interfering with helper T-cell function.

1989 • 5 citations