Cultured Epidermal Langerhans Cells Activate Effector T Cells for Contact Sensitivity

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro.

1985 • 1,141 citations

Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors

1988 • 1,086 citations

Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies.

1987 • 1,060 citations

Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB.

1980 • 983 citations

Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones.

1987 • 966 citations

Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1

1985 • 749 citations

Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate. Functional and morphological studies.

1987 • 592 citations

Granulocyte/macrophage colony-stimulating factor and interleukin 1 mediate the maturation of murine epidermal Langerhans cells into potent immunostimulatory dendritic cells.

1988 • 565 citations

Granulocyte/macrophage colony-stimulating factor is essential for the viability and function of cultured murine epidermal Langerhans cells.

1987 • 523 citations

T-cell and mast cell lines respond to B-cell stimulatory factor 1.

1986 • 381 citations

Impairment of antigen-presenting cell function by ultraviolet radiation.

1979 • 259 citations

Immunologic properties of purified epidermal Langerhans cells. Distinct requirements for stimulation of unprimed and sensitized T lymphocytes.

1986 • 238 citations

Dendritic cells and the initiation of contact sensitivity to fluorescein isothiocyanate.

1986 • 221 citations

Relationship between epidermal Langerhans cell density ATPase activity and the induction of contact hypersensitivity.

1981 • 180 citations

Role of antigen-presenting cells in the development and persistence of contact hypersensitivity.

1980 • 174 citations

Enhanced antigen-presenting capacity of cultured Langerhans' cells is associated with markedly increased expression of Ia antigen.

1987 • 154 citations

Mechanism of systemic immune suppression by UV irradiation in vivo. II. The UV effects on number and morphology of epidermal Langerhans cells and the UV-induced suppression of contact hypersensitivity have different wavelength dependencies.

1984 • 143 citations

Genetic basis of ultraviolet-B effects on contact hypersensitivity

1988 • 114 citations

Activation and expansion of hapten- and protein-specific T helper cells from nonsensitized mice.

1988 • 93 citations

Cutaneous Dermal Ia+ Cells Are Capable of Initiating Delayed Type Hypersensitivity Responses

1990 • 90 citations

The Role of Epidermal Cells in the Induction and Suppression of Contact Sensitivity

1981 • 87 citations

Tolerance and contact sensitivity to DNFA in mice. VIII. Identification of distinct T cell subpopulations that mediate in vivo and in vitro manifestations of delayed hypersensitivity.

1978 • 84 citations

T helper cells grown with hapten‐modified cultured Langerhans' cells produce interleukin 4 and stimulate IgE production by B cells

1989 • 82 citations

Interleukin 2-diphtheria toxin fusion protein can abolish cell-mediated immunity in vivo.

1988 • 78 citations

Langerhans Cell Function Dictates Induction of Contact Hypersensitivity or Unresponsiveness to DNFB in Syrian Hamsters

1981 • 66 citations

Immunologic effects of whole-body ultraviolet irradiation: selective defect in splenic adherent cell function in vitro.

1980 • 62 citations

In vivo effects of GK1.5 (anti-L3T4a) monoclonal antibody on induction and expression of delayed-type hypersensitivity

1985 • 59 citations

Systemic suppression of contact hypersensitivity by UVB radiation is unrelated to the UVB-induced alterations in the morphology and number of Langerhans cells.

1984 • 54 citations

Langerhans Cells: Functional Aspects Revealed by in Vivo Grafting Studies

1980 • 52 citations

Tolerance and Contact Sensitivity to DNFB in Mice

1978 • 50 citations

Subtypes of helper cells. Non-inflammatory type 1 helper T cells.

1988 • 40 citations

Anti-interleukin 2 receptor antibody suppresses delayed-type hypersensitivity to foreign and syngeneic antigens.

1986 • 39 citations

Selective inhibition of the generation of T suppressor cells of contact sensitivity in vitro by interferon.

1987 • 34 citations

Dendritic cells and T cells transfer sensitization for delayed-type hypersensitivity after skin painting with contact sensitizer.

1989 • 32 citations

In vitro induction of delayed‐type hypersensitivity

1979 • 30 citations

Intravenously Injected, TNP-Derivatized, Langerhans Cell-Enriched Epidermal Cells Induce Contact Hypersensitivity in Syrian Hamsters

1985 • 29 citations

Inhibition of the T suppressor circuit of delayed-type hypersensitivity by interferon.

1984 • 26 citations

Effect of depletion of epidermal dendritic cells on the induction of contact sensitivity in the guinea-pig

1985 • 21 citations

INDUCTION OF H-2-RESTRICTED CONTACT HYPERSENSITIVITY BY HAPTEN-DERIVATIZED SKIN GRAFTS

1984 • 20 citations

Strain Variation in the Induction of Tolerance by Epicutaneous Application of Trinitrochlorobenzene

1983 • 17 citations

The in vitro induction of T cells which mediate delayed-type hypersensitivity toward horse red blood cells

1979 • 16 citations

Effects of ultraviolet irradiation on surface marker expression by epidermal immunocompetent cells and contact sensitization to dinitrofluorobenzene in mice

1987 • 13 citations

Characterization of Primary T Helper Cell Activation and T Helper Cell Lines Stimulated by Hapten-modified, Cultured Langerhans Cells

1989 • 13 citations

Induction of Contact Sensitivity to a Broad Variety of Allergens with Haptenized Macrophages

1984 • 11 citations

Induction of sensitization and tolerance in contact sensitivity with haptenated epidermal cells in the guinea-pig.

1987 • 3 citations

Experimental and clinical topical cyclosporin treatment in hair growth

1988 • 2 citations