Coexpression of mu and gamma 1 heavy chains can occur by a discontinuous transcription mechanism from the same unrearranged chromosome.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Genomic sequencing.

1984 • 8,343 citations

Domains in viroids: evidence of intermolecular RNA rearrangements and their contribution to viroid evolution.

1985 • 430 citations

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching.

1986 • 344 citations

Organization of the constant-region gene family of the mouse immunoglobulin heavy chain

1982 • 323 citations

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes.

1988 • 285 citations

Messenger and Heterogeneous Nuclear RNA in HeLa Cells: Differential Inhibition by Cordycepin

1970 • 253 citations

Induction of RNA-stabilized DMA conformers by transcription of an immunoglobulin switch region

1990 • 237 citations

Immunoglobulin Class Switching: Molecular and Cellular Analysis

1990 • 224 citations

Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching.

1986 • 220 citations

Regulation of T-cell receptor γ-chain RNA expression in murine Thy-1+ dendritic epidermal cells

1987 • 213 citations

Immunoglobulin class switching

1984 • 208 citations

GENE AND TRANSCRIPTION UNIT MAPPING BY RADIATION EFFECTS

1978 • 172 citations

Synthesis of germ-line gamma 1 immunoglobulin heavy-chain transcripts in resting B cells: induction by interleukin 4 and inhibition by interferon gamma.

1989 • 172 citations

The molecular biology of immunoglobulin D

1984 • 152 citations

Human U1 Loci: Genes for human U1 RNA have dramatically similar genomic environments

1982 • 140 citations

Rapid induction of transcription of unrearranged S gamma 1 switch regions in activated murine B cells by interleukin 4.

1989 • 134 citations

Expression of lymphocyte surface IgE does not require switch recombination

1982 • 133 citations

Secondary structure maps of ribosomal RNA

1974 • 129 citations

Transcriptional regulation of the mu-delta heavy chain locus in normal murine B lymphocytes.

1984 • 112 citations

T Cell‐Derived Lymphokines That Induce IgM and IgG Secretion in Activated Murine B Cells

1984 • 109 citations

Mouse IgA heavy chain gene sequence: implications for evolution of immunoglobulin hinge axons.

1981 • 99 citations

Antibodies of the secondary response can be expressed without switch recombination in normal mouse B cells.

1984 • 88 citations

Simultaneous expression of immunoglobulin mu and delta heavy chains by a cloned B-cell lymphoma: a single copy of the VH gene is shared by two adjacent CH genes.

1982 • 79 citations

Structure and expression of germline immunoglobulin γ³ heavy chain gene transcripts: implications for mitogen and lymphokine directed class-switching

1990 • 76 citations

Trans-splicing as a possible molecular mechanism for the multiple isotype expression of the immunoglobulin gene.

1991 • 73 citations

Evidence for splicing of interrupted immunoglobulin variable and constant region sequences in nuclear RNA

1978 • 71 citations

Cloning of mouse immunoglobulin epsilon gene and its location within the heavy chain gene cluster.

1981 • 70 citations

Structure of the Constant and 3′ Untranslated Regions of the Murine γ2b Heavy Chain Messenger RNA

1979 • 66 citations

Structural analysis of the murine IgG3 constant region gene.

1984 • 64 citations

Characterization of a spontaneous murine B cell leukemia (BCL1). I. Cell surface expression of IgM, IgD, Ia, and FcR.

1979 • 64 citations

Double isotype production by a neoplastic B cell line. II. Allelically excluded production of mu and gamma 1 heavy chains without CH gene rearrangement.

1986 • 61 citations

Trans splicing: Variation on a familiar theme?

1987 • 58 citations

An in vitro line of the B cell tumor BCL1 can be activated by LPS to secrete IgM1.

1980 • 54 citations

The ubiquitous octamer-binding protein(s) is sufficient for transcription of immunoglobulin genes.

1990 • 44 citations

Nuclear Transcripts of Mouse Heavy Chain Immunoglobulin Genes Contain Only the Expressed Class of C-Region Sequences

1979 • 37 citations

Illegitimate recombination generates a class switch from C mu to C delta in an IgD-secreting plasmacytoma.

1984 • 36 citations

Structure of Germline Immunoglobulin Heavy-Chain<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="E1"><mml:mi>γ</mml:mi></mml:math>1 Transcripts in Interleukin 4 Treated Mouse Spleen Cells

1989 • 35 citations

Effect of T cell-derived lymphokines containing B cell differentiation factor(s) for IgG (BCDF gamma) on gamma-specific mRNA in murine B cells.

1983 • 30 citations

Double isotype production by a neoplastic B cell line. I. Cellular and biochemical characterization of a variant of BCL1 that expresses and secretes both IgM and IgG1.

1986 • 26 citations

Human neoplastic B cells express more than two isotypes of immunoglobulins without deletion of heavy-chain constant-region genes.

1987 • 25 citations

B cells that simultaneously express surface IgM and IgE in Nippostrongylus brasiliensis-infected SJA/9 mice do not provide evidence for isotype switching without gene deletion.

1985 • 25 citations

Mouse spleen and IgD-secreting plasmacytomas contain multiple IgD δ chain RNAs

1982 • 25 citations

The Ubiquitous Octamer-Binding Protein(s) Is Sufficient for Transcription of Immunoglobulin Genes

1990 • 18 citations

[54] Mapping viral mRNAs by sandwich hybridization

1980 • 12 citations

Mutation of 3' splice sites in two different class I genes results in different usage of cryptic splice sites.

1989 • 7 citations

The effect of T cell-derived lymphokines on the levels of isotype-specific RNA in normal B cells.

1985 • 6 citations

The C mu gene is transcribed in IgG bearing B lymphocytes.

1987 • 4 citations