Synthesis of germ-line gamma 1 immunoglobulin heavy-chain transcripts in resting B cells: induction by interleukin 4 and inhibition by interferon gamma.

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

1987 • 1,936 citations

Rapid transfer of DNA from agarose gels to nylon membranes

1985 • 1,810 citations

Fundamental techniques in virology.

1969 • 1,768 citations

Spliced early mRNAs of simian virus 40

1978 • 817 citations

B cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells.

1986 • 797 citations

Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1

1985 • 749 citations

A T cell activity that enhances polyclonal IgE production and its inhibition by interferon-gamma.

1986 • 727 citations

Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

1985 • 710 citations

Increased expression of Ia antigens on resting B cells: an additional role for B-cell growth factor.

1984 • 438 citations

Regulation of Genome Rearrangement Events during Lymphocyte Differentiation

1986 • 422 citations

Serological, biochemical, and functional identity of B cell-stimulatory factor 1 and B cell differentiation factor for IgG1.

1985 • 410 citations

Differential regulation of IgG1 and IgE synthesis by interleukin 4.

1988 • 389 citations

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching.

1986 • 344 citations

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes.

1988 • 285 citations

Mitogen- and IL-4-regulated expression of germ-line Ig γ2b transcripts: Evidence for directed heavy chain class switching

1988 • 277 citations

Immunoglobulin class switching

1984 • 208 citations

Mitogen plus interleukin 4 induction of C epsilon transcripts in B lymphoid cells.

1988 • 208 citations

B cell stimulatory factor-1 (interleukin 4) prepares resting murine B cells to secrete IgG1 upon subsequent stimulation with bacterial lipopolysaccharide.

1987 • 154 citations

Structure and expression of germ line immunoglobulin gamma 2b transcripts.

1988 • 136 citations

Interleukin 4 instructs uncommitted B lymphocytes to switch to IgG_l and IgE

1988 • 119 citations

B-cell growth factor (B-cell growth factor I or B-cell-stimulating factor, provisional 1) is a differentiation factor for resting B cells and may not induce cell growth.

1985 • 118 citations

IL-4 induces co-expression of intrinsic membrane IgG1 and IgE by murine B cells stimulated with lipopolysaccharide.

1988 • 101 citations

Class switch recombination is IgG1 specific on active and inactive IgH loci of IgG1-secreting B-cell blasts.

1986 • 95 citations

Directed Ig class switch recombination in activated murine B cells.

1987 • 94 citations

Clonal analysis of B cells induced to secrete IgG by T cell-derived lymphokine(s).

1984 • 87 citations

DNA sequence of the murine gamma 1 switch segment reveals novel structural elements.

1986 • 86 citations

Switch region content of hybridomas: the two spleen cell Igh loci tend to rearrange to the same isotype.

1987 • 71 citations

Control of Immunoglobulin Class Switch Recombination

1986 • 60 citations

Properties of a mouse ribosomal protein promoter.

1986 • 51 citations

Sequence analysis of cloned cDNA encoding part of an immunoglobulin heavy chain

1979 • 39 citations

Structure and Expression of Germ Line Immunoglobulin γ2b Transcripts

1988 • 36 citations

The murine B cell response to TNP-polyacrylamide beads: the relationship between the epitope density of the antigen and the requirements for T cell help and surface IgD.

1980 • 34 citations

Effect of T cell-derived lymphokines containing B cell differentiation factor(s) for IgG (BCDF gamma) on gamma-specific mRNA in murine B cells.

1983 • 30 citations

Small and large B cells respond differently to T cell-derived B cell growth and differentiation factors.

1985 • 29 citations

Activation of the gamma 1 gene by lipopolysaccharide and T cell-derived lymphokines containing a B cell differentiation factor for IgG1 (BCDF gamma).

1985 • 16 citations