Dynamic and Differential in Vivo Modifications of the Isoform HMGA1a and HMGA1b Chromatin Proteins

An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

1994 • 6,412 citations

Large-scale analysis of the yeast proteome by multidimensional protein identification technology

2001 • 4,766 citations

Direct analysis of protein complexes using mass spectrometry

1999 • 2,242 citations

Post-translational modification of p53 in tumorigenesis

2004 • 1,227 citations

Analysis of Proteins and Proteomes by Mass Spectrometry

2001 • 1,178 citations

The A.T-DNA-binding domain of mammalian high mobility group I chromosomal proteins. A novel peptide motif for recognizing DNA structure.

1990 • 674 citations

Binary switches and modification cassettes in histone biology and beyond

2003 • 628 citations

Protein Sequencing and Identification Using Tandem Mass Spectrometry

2000 • 541 citations

Molecular biology of HMGA proteins: hubs of nuclear function

2001 • 527 citations

Protein Sequencing and Identification Using Tandem Mass Spectrometry

2000 • 441 citations

Linking the epigenetic ‘language’ of covalent histone modifications to cancer

2004 • 385 citations

Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine.

2002 • 383 citations

The solution structure of an HMG-I(Y)–DNA complex defines a new architectural minor groove binding motif

1997 • 372 citations

Revised nomenclature for high mobility group (HMG) chromosomal proteins

2001 • 369 citations

HMGI/Y proteins: flexible regulators of transcription and chromatin structure

2001 • 346 citations

Acetylation of HMG I(Y) by CBP Turns off IFNβ Expression by Disrupting the Enhanceosome

1998 • 321 citations

Alternative processing of mRNAs encoding mammalian chromosomal high-mobility-group proteins HMG-I and HMG-Y.

1989 • 241 citations

Architectural Transcription Factor HMGI(Y) Promotes Tumor Progression and Mesenchymal Transition of Human Epithelial Cells

2001 • 236 citations

Nuclear phosphoproteins HMGA and their relationship with chromatin structure and cancer

2004 • 225 citations

Organization, inducible-expression and chromosome localization of the human HMG-I(Y) nonhistone protein gene

1993 • 205 citations

Coordination of a Transcriptional Switch by HMGI(Y) Acetylation

2001 • 195 citations

Role of protein methylation in chromatin remodeling and transcriptional regulation

2001 • 186 citations

Chromatin unfolding and activation by HMGN**The nomenclature of the HMG protein superfamily has been recently revised (see Ref. 12 and http://www.informatics.jax.org/mgihome/nomen/genefamilies/hmgfamily.shtml). chromosomal proteins

2001 • 174 citations

The oncogenic properties of the HMG-I gene family.

2000 • 166 citations

An Approach to Locate Phosphorylation Sites in a Phosphoprotein: Mass Mapping by Combining Specific Enzymatic Degradation with Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry

1994 • 142 citations

Phosphorylation by cdc2 kinase modulates DNA binding activity of high mobility group I nonhistone chromatin protein.

1991 • 128 citations

Phosphorylation of the DNA-binding domain of nonhistone high-mobility group I protein by cdc2 kinase: reduction of binding affinity.

1991 • 124 citations

HMGI(Y) and HMGI-C Dysregulation

1999 • 121 citations

Identification of high mobility group protein I(Y) as potential progression marker for prostate cancer by differential hybridization analysis.

1991 • 113 citations

Structure and Function of the HMGI(Y) Family of Architectural Transcription Factors

2000 • 105 citations

Purification and postsynthetic modifications of friend erythroleukemic cell high mobility group protein HMG-I

1986 • 100 citations

Automated Protein Identification Using Microcolumn Liquid Chromatography-Tandem Mass Spectrometry

2003 • 88 citations

High mobility group I (Y) proteins bind HIPK2, a serine-threonine kinase protein which inhibits cell growth

2001 • 87 citations

Peer Reviewed: Mining Genomes with MS

1996 • 87 citations

Chromatin Structure and Dynamics: State-of-the-Art

2004 • 74 citations

“Colored” Noise Waveforms and Quadrupole Excitation for the Dynamic Range Expansion of Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

1996 • 70 citations

Differential in Vivo Modifications of the HMGI(Y) Nonhistone Chromatin Proteins Modulate Nucleosome and DNA Interactions

2000 • 66 citations

A retrospective study of high mobility group protein I(Y) as progression marker for prostate cancer determined by in situ hybridization

1996 • 63 citations

Purification and assays for high mobility group HMG-I(Y) protein function

1999 • 60 citations

Differential expression of histone post-translational modifications in acute myeloid and chronic lymphocytic leukemia determined by high-pressure liquid chromatography and mass spectrometry

2003 • 59 citations

Specific A·T DNA sequence binding of RP-HPLC purified HMG-I

1987 • 57 citations

Identification of sites on chromosomal protein HMG‐I phosphorylated by casein kinase II

1989 • 55 citations

On the phosphorylation of low molecular mass HMG (high mobility group) proteins in Ehrlich ascites cells

1985 • 54 citations

A Link between Apoptosis and Degree of Phosphorylation of High Mobility Group A1a Protein in Leukemic Cells

2001 • 53 citations

High‐mobility‐group proteins P1, I and Y as substrates of the M‐phase‐specific p^34cdc2/cyclin^cdc13 kinase

1991 • 51 citations

Mass spectrometric analysis of the HMGY protein from Lewis lung carcinoma. Identification of phosphorylation sites.

1992 • 50 citations

Phosphorylation of HMG‐I by Protein Kinase C Attenuates Its Binding Affinity to the Promoter Regions of Protein Kinase C γ and Neurogranin/RC3 Genes

2000 • 49 citations

In Vivo Posttranslational Modifications of the High Mobility Group A1a Proteins in Breast Cancer Cells of Differing Metastatic Potential

2004 • 48 citations

During Apoptosis of Tumor Cells HMGA1a Protein Undergoes Methylation: Identification of the Modification Site by Mass Spectrometry

2003 • 47 citations

Chromatin (dis)Organization and Cancer: BUR-binding Proteins as Biomarkers for Cancer

2002 • 43 citations

Retraction: Overexpression of Proteins HMGA1 Induces Cell Cycle Deregulation and Apoptosis in Normal Rat Thyroid Cells

2018 • 40 citations

Protein profiles and identification of high performance liquid chromatography isolated proteins of cancer cell lines using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

1998 • 33 citations

Cell cycle regulation and functions of HMG-I(Y)

1995 • 30 citations

High mobility group A1 is expressed in metastatic adenocarcinoma to the liver and intrahepatic cholangiocarcinoma, but not in hepatocellular carcinoma: its potential use in the diagnosis of liver neoplasms

2003 • 30 citations

The metaphase specific phosphorylation of HMG I

1990 • 26 citations

HMGA proteins as therapeutic drug targets.

2003 • 26 citations

Fractionation and identification of metaphase-specific phosphorylated forms of high-mobility-group proteins

1987 • 24 citations