Telomerase Activity in Immortalized Endothelial Cells Undergoing p53-Mediated Apoptosis

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1994 • 7,043 citations

Telomeres shorten during ageing of human fibroblasts

1990 • 5,530 citations

Identification of a specific telomere terminal transferase activity in tetrahymena extracts

1985 • 3,331 citations

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.

1992 • 2,096 citations

Telomere reduction in human colorectal carcinoma and with ageing

1990 • 1,672 citations

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

1989 • 1,509 citations

TELOMERE LENGTH REGULATION

1996 • 1,010 citations

Telomerase activation by the E6 gene product of human papillomavirus type 16

1996 • 825 citations

Developmental and tissue-specific regulation of mouse telomerase and telomere length.

1995 • 686 citations

In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs

1990 • 632 citations

Spontaneous transformation and immortalization of human endothelial cells

1990 • 428 citations

Regulation of Telomerase Activity in Immortal Cell Lines

1996 • 360 citations

Telomeres and telomerase in aging and cancer

1995 • 328 citations

Differentiation of immortal cells inhibits telomerase activity.

1995 • 269 citations

The Human Papillomavirus Type 16 E6 and E7 Oncoproteins Dissociate Cellular Telomerase Activity from the Maintenance of Telomere Length

1997 • 115 citations

Generation and identification of recombinant adenovirus by liposome-mediated transfection and PCR analysis.

1993 • 111 citations

Telomerase activity is repressed during differentiation of maturation-sensitive but not resistant human tumor cell lines.

1996 • 105 citations

Telomerase activity in human acute myelogenous leukemia: inhibition of telomerase activity by differentiation-inducing agents.

1996 • 103 citations

Evidence for UV-associated activation of telomerase in human skin.

1997 • 96 citations

Immortalization of human mammary epithelial cells transfected with mutant p53 (273his).

1996 • 72 citations

Telomere Reduction and Telomerase Inactivation during Neuronal Cell Differentiation

1996 • 65 citations

Differential Inhibition of Telomerase Activity during Induction of Differentiation in Hematopoietic, Melanoma, and Glioma Cells in Culture

1997 • 18 citations

Expression of Bax, Bcl-2, Waf-1, and PCNA gene products in an immortalized human endothelial cell line undergoing p53-mediated apoptosis

1997 • 8 citations

Introduction of p21Waf1/Cip1 gene into a carcinoma cell line of the uterine cervix with inactivated p53

1997 • 7 citations