Telomerase activity is repressed during differentiation of maturation-sensitive but not resistant human tumor cell lines.

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1994 • 7,043 citations

Structure and function of telomeres

1991 • 3,524 citations

The RNA Component of Human Telomerase

1995 • 2,243 citations

Telomere length predicts replicative capacity of human fibroblasts.

1992 • 2,209 citations

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.

1992 • 2,096 citations

Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.

1994 • 1,133 citations

Activation of telomerase in human lymphocytes and hematopoietic progenitor cells.

1995 • 871 citations

Correlating telomerase activity levels with human neuroblastoma outcomes

1995 • 631 citations

Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Differentiation in vivo and in vitro.

1984 • 612 citations

Telomerase Activity in Small-Cell and Non-Small-Cell Lung Cancers

1995 • 447 citations

Telomerase, Cell Immortality, and Cancer

1994 • 405 citations

Telomerase activity associated with acquisition of malignancy in human colorectal cancer.

1995 • 361 citations

Differentiation of immortal cells inhibits telomerase activity.

1995 • 269 citations

Different patterns of glycolipid antigens are expressed following differentiation of TERA-2 human embryonal carcinoma cells induced by retinoic acid, hexamethylene bisacetamide (HMBA) or bromodeoxyuridine (BUdR)

1990 • 105 citations

Response and resistance to retinoic acid are mediated through the retinoic acid nuclear receptor gamma in human teratocarcinomas.

1994 • 54 citations

Retinoic acid causes a decline in TGF-alpha expression, cloning efficiency, and tumorigenicity in a human embryonal cancer cell line.

1990 • 48 citations

Overexpression of the retinoic acid receptor gamma directly induces terminal differentiation of human embryonal carcinoma cells.

1995 • 42 citations

Growth suppression of acute promyelocytic leukemia cells having increased expression of the non-rearranged alleles: RAR alpha or PML.

1995 • 36 citations

All-trans-retinoic acid and hexamethylene bisacetamide (HMBA) regulate TGF-α and Hst-1/kFGF expression in differentiation sensitive but not in resistant human teratocarcinomas

1994 • 20 citations