Activation of the Erk8 Mitogen-activated Protein (MAP) Kinase by RET/PTC3, a Constitutively Active Form of the RET Proto-oncogene

Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human

1999 • 2,692 citations

Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor

1996 • 1,946 citations

The GDNF family: Signalling, biological functions and therapeutic value

2002 • 1,722 citations

Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret

1994 • 1,589 citations

Thyroid carcinoma

2003 • 864 citations

Regulation of the c-Abl and Bcr–Abl tyrosine kinases

2004 • 467 citations

RET/PTC Rearrangement in Thyroid Tumors

2002 • 464 citations

c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF

1999 • 420 citations

Molecular characterization of RET/PTC3; a novel rearranged version of the RETproto-oncogene in a human thyroid papillary carcinoma.

1994 • 364 citations

Disease associated mutations at valine 804 in the RET receptor tyrosine kinase confer resistance to selective kinase inhibitors

2004 • 239 citations

Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor

2000 • 222 citations

A Network of Mitogen-Activated Protein Kinases Links G Protein-Coupled Receptors to the c-jun Promoter: a Role for c-Jun NH₂-Terminal Kinase, p38s, and Extracellular Signal-Regulated Kinase 5

1999 • 212 citations

The Full Oncogenic Activity of Ret/ptc2 Depends on Tyrosine 539, a Docking Site for Phospholipase Cγ

1996 • 199 citations

Multiple Mitogen-Activated Protein Kinase Signaling Pathways Connect the Cot Oncoprotein to the c-junPromoter and to Cellular Transformation

2000 • 198 citations

Mutagenic analysis of the roles of SH2 and SH3 domains in regulation of the Abl tyrosine kinase.

1994 • 175 citations

Minireview: RET: Normal and Abnormal Functions

2004 • 174 citations

RET mutations in human disease

1996 • 173 citations

Regulation of c-myc expression by PDGF through Rho GTPases

2001 • 137 citations

Docking Protein FRS2 Links the Protein Tyrosine Kinase RET and Its Oncogenic Forms with the Mitogen-Activated Protein Kinase Signaling Cascade

2001 • 136 citations

The kinase inhibitor PP1 blocks tumorigenesis induced by RET oncogenes.

2002 • 133 citations

Molecular heterogeneity of RET loss of function in Hirschsprung's disease.

1996 • 132 citations

Signalling of the Ret receptor tyrosine kinase through the c-Jun NH2-terminal protein kinases (JNKs): evidence for a divergence of the ERKs and JNKs pathways induced by Ret

1998 • 130 citations

ERK8, a New Member of the Mitogen-activated Protein Kinase Family

2002 • 125 citations

The Unique C-terminal Tail of the Mitogen-activated Protein Kinase ERK5 Regulates Its Activation and Nuclear Shuttling

2004 • 117 citations

Tyrosine 981, a Novel Ret Autophosphorylation Site, Binds c-Src to Mediate Neuronal Survival

2004 • 110 citations

Regulation of p73 by c-Abl through the p38 MAP kinase pathway

2002 • 109 citations

ERK7 Is an Autoactivated Member of the MAPK Family

2001 • 86 citations

Controlling Abl: auto-inhibition and co-inhibition?

2004 • 66 citations

Cell signalling and gene expression mediated by RET tyrosine kinase

2003 • 33 citations

Modulation of the p38 MAPK (mitogen-activated protein kinase) pathway through Bcr/Abl: implications in the cellular response to Ara-C

2005 • 19 citations

A high phosphorylation state and increased activity of the TRE motif in the NIH3T3 cell transformant induced by retTPC

1991 • 5 citations