The Genetic Approach in Pulmonary Fibrosis: Can It Provide Clues to This Complex Disease?

Idiopathic Pulmonary Fibrosis: Diagnosis and Treatment

2000 • 2,535 citations

Idiopathic Pulmonary Fibrosis

2001 • 956 citations

A Mutation in the Surfactant Protein C Gene Associated with Familial Interstitial Lung Disease

2001 • 888 citations

ABCA3Gene Mutations in Newborns with Fatal Surfactant Deficiency

2004 • 648 citations

Heterozygosity for a Surfactant Protein C Gene Mutation Associated with Usual Interstitial Pneumonitis and Cellular Nonspecific Interstitial Pneumonitis in One Kindred

2002 • 635 citations

Hydrophobic Surfactant Proteins in Lung Function and Disease

2002 • 493 citations

Genetic Modifiers of Lung Disease in Cystic Fibrosis

2005 • 486 citations

Clinical and Pathologic Features of Familial Interstitial Pneumonia

2005 • 406 citations

ABCA3 Mutations Associated with Pediatric Interstitial Lung Disease

2005 • 292 citations

Genetic mutations in surfactant protein C are a rare cause of sporadic cases of IPF

2004 • 267 citations

A Surfactant Protein C Precursor Protein BRICHOS Domain Mutation Causes Endoplasmic Reticulum Stress, Proteasome Dysfunction, and Caspase 3 Activation

2005 • 250 citations

Nationwide prevalence of sporadic and familial idiopathic pulmonary fibrosis: evidence of founder effect among multiplex families in Finland

2002 • 238 citations

Adult familial cryptogenic fibrosing alveolitis in the United Kingdom

2000 • 229 citations

Pneumonitis and Emphysema in sp-C Gene Targeted Mice

2003 • 212 citations

SURFACTANT PROTEIN C BIOSYNTHESIS AND ITS EMERGING ROLE IN CONFORMATIONAL LUNG DISEASE

2004 • 196 citations

Mutations in the Surfactant Protein C Gene Associated With Interstitial Lung Disease

2002 • 192 citations

Increased Risk of Fibrosing Alveolitis Associated with Interleukin-1 Receptor Antagonist and Tumor Necrosis Factor- α Gene Polymorphisms

2000 • 186 citations

A common mutation in the surfactant protein C gene associated with lung disease

2005 • 182 citations

Transforming Growth Factor-β₁ Gene Polymorphisms Are Associated with Disease Progression in Idiopathic Pulmonary Fibrosis

2003 • 171 citations

Surfactant protein�A and B genetic variants predispose to idiopathic pulmonary fibrosis

2003 • 167 citations

Increased and Prolonged Pulmonary Fibrosis in Surfactant Protein C-Deficient Mice Following Intratracheal Bleomycin

2005 • 161 citations

Interstitial lung disease in a baby with a de novo mutation in the SFTPC gene

2004 • 159 citations

Familial Idiopathic Pulmonary Fibrosis

2005 • 157 citations

Expression of a Human Surfactant Protein C Mutation Associated with Interstitial Lung Disease Disrupts Lung Development in Transgenic Mice

2003 • 154 citations

Surfactant protein deficiency in familial interstitial lung disease

2001 • 147 citations

Analysis of Tumor Necrosis Factor- α , Lymphotoxin- α , Tumor Necrosis Factor Receptor II, and Interleukin-6 Polymorphisms in Patients with Idiopathic Pulmonary Fibrosis

2001 • 141 citations

Mutation of SFTPC in infantile pulmonary alveolar proteinosis with or without fibrosing lung disease

2004 • 140 citations

Surfactant protein gene A, B, and D marker alleles in chronic obstructive pulmonary disease of a Mexican population

2001 • 134 citations

Interleukin-1 Gene Cluster Polymorphisms in Sarcoidosis and Idiopathic Pulmonary Fibrosis

2002 • 131 citations

Progressive Lung Disease and Surfactant Dysfunction with a Deletion in Surfactant Protein C Gene

2003 • 124 citations

The pathogenesis of pulmonary fibrosis: Is there a fibrosis gene?

1997 • 116 citations

Distribution of novel polymorphisms of the interleukin-8 and CXC receptor 1 and 2 genes in systemic sclerosis and cryptogenic fibrosing alveolitis

2000 • 115 citations

Genetics of fibrosing lung diseases

2005 • 100 citations

Transforming growth factor-beta (TGF-β1) genotype and lung allograft fibrosis

1999 • 96 citations

Pulmonary fibrosis in families.

2003 • 87 citations

A family study of idiopathic pulmonary fibrosis

1965 • 87 citations

FAMILIAL FIBROCYSTIC PULMONARY DYSPLASIA AND ITS RELATION TO THE HAMMAN-RICH SYNDROME

1959 • 81 citations

Idiopathic Pulmonary Fibrosis; Its Occurrence in Identical Twin Sisters

1950 • 76 citations

Complement Receptor 1 Gene Polymorphisms in Sarcoidosis

2002 • 68 citations

Cytokine gene polymorphisms in idiopathic pulmonary fibrosis

2004 • 60 citations

Complement Receptor 1 Gene Polymorphisms Are Associated with Idiopathic Pulmonary Fibrosis

2003 • 51 citations

Familial Pulmonary Fibrosis

1951 • 46 citations

Increased D allele frequency of the angiotensin-converting enzyme gene in pulmonary fibrosis

2001 • 44 citations

Analysis of IL-12 p40 subunit gene and IFN-γ G5644A polymorphisms in Idiopathic Pulmonary Fibrosis

2003 • 44 citations

Analysis of an IL-10 polymorphism in idiopathic pulmonary fibrosis

2003 • 31 citations

A Plasminogen Activator Inhibitor-1 Promoter Polymorphism and Idiopathic Interstitial Pneumonia

2003 • 25 citations

Familial Idiopathic Pulmonary Fibrosis

2004 • 23 citations

Idiopathic Pulmonary Fibrosis Can Be an Autosomal Dominant Trait in Some Families

2001 • 18 citations

A FAMILY STUDY OF IDIOPATHIC PULMONARY FIBROSIS: A POSSIBLE DYSPROTEINEMIC AND GENETICALLY DETERMINED DISEASE.

1964 • 13 citations

Distribution of novel polymorphisms of the interleukin-8 and CXC receptor 1 and 2 genes in systemic sclerosis and cryptogenic fibrosing alveolitis

2000 • 7 citations

A Common Mutation in the Surfactant Protein C Gene Associated With Lung Disease

2006 • 6 citations