Cytosolic Na+ controls and epithelial Na+ channel via the Go guanine nucleotide-binding regulatory protein.

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

ADP ribosylation of the specific membrane protein of C6 cells by islet-activating protein associated with modification of adenylate cyclase activity.

1982 • 600 citations

Guanosine 5'-O-(2-thiodiphosphate). An inhibitor of adenylate cyclase stimulation by guanine nucleotides and fluoride ions.

1979 • 382 citations

Cell-specific expression of epithelial sodium channel alpha, beta, and gamma subunits in aldosterone-responsive epithelia from the rat: localization by in situ hybridization and immunocytochemistry.

1994 • 376 citations

Current—voltage curve of sodium channels and concentration dependence of sodium permeability in frog skin

1977 • 321 citations

Homocellular regulatory mechanisms in sodium-transporting epithelia: avoidance of extinction by “flush-through”

1981 • 273 citations

Concentration dependence of currents through single sodium-selective pores in frog skin

1979 • 155 citations

Na+ transport pathways in secretory acinar cells: membrane cross talk mediated by [Cl-]i

1994 • 117 citations

Molecular properties of epithelial, amiloride‐blockable Na ⁺ channels

1994 • 112 citations

Intracellular pH controls cell membrane Na+ and K+ conductances and transport in frog skin epithelium.

1988 • 111 citations

mu-Opioid receptor-mediated reduction of neuronal calcium current occurs via a G(o)-type GTP-binding protein

1994 • 106 citations

Conductance and gating of epithelial Na channels from rat cortical collecting tubule. Effects of luminal Na and Li.

1988 • 104 citations

Na+ and Cl? conductances are controlled by cytosolic Cl? concentration in the intralobular duct cells of mouse mandibular glands

1993 • 100 citations

Feedback regulation of Na channels in rat CCT. II. Effects of inhibition of Na entry

1993 • 93 citations

Intrinsic regulation of apical sodium entry in epithelia

1991 • 87 citations

Purified epithelial Na+ channel complex contains the pertussis toxin-sensitive G alpha i-3 protein.

1992 • 71 citations

Oscillations of Cytosolic Sodium During Calcium Oscillations in Exocrine Acinar Cells

1991 • 61 citations

Control of the amiloride‐sensitive Na+ current in mouse salivary ducts by intracellular anions is mediated by a G protein.

1995 • 56 citations

Amiloride-sensitive Na+ current in the granular duct cells of mouse mandibular glands

1993 • 45 citations

Protein kinase A phosphorylation and G protein regulation of purified renal Na+ channels in planar bilayer membranes.

1994 • 43 citations

Characterization of the Cl? conductance in the granular duct cells of mouse mandibular glands

1994 • 36 citations

Regulation by Na+ and Ca2+ of renal epithelial Na+ channels reconstituted into planar lipid bilayers.

1995 • 29 citations

HCO 3 ? -dependent ACh-activated Na+ influx in sheep parotid secretory endpieces

1995 • 26 citations

Control of the Amiloride-Sensitive Na + Current in Salivary Duct Cells by Extracellular Sodium

1996 • 25 citations

Regulation of [Na+] in Resting and Stimulated Submandibular Salivary Ducts

1995 • 24 citations

Control of intracellular Ca2+ by adrenergic and muscarinic agonists in mouse mandibular ducts and endpieces

1993 • 21 citations

Demonstration of a novel apamin-insensitive calcium-activated K+ channel in mouse pancreatic B cells

1993 • 20 citations

Augmentation of calcium channel currents in response to G protein activation by GTP gamma S in chick sensory neurons

1994 • 20 citations

[21] Specificity and functional applications of antipeptide antisera which identify G-protein α subunits

1994 • 14 citations

Na+ channels in membrane vesicles from intralobular salivary ducts

1995 • 10 citations

Localization of the G-protein G(o) in exocrine glands.

1994 • 7 citations