Characterization of an endogenous RNA transcript with homology to the antisense strand of the human c-myc gene.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

The use of thin acrylamide gels for DNA sequencing

1978 • 1,449 citations

λ ZAP: a bacteriophage λ expression vector within vivoexcision properties

1988 • 1,394 citations

A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells

1986 • 834 citations

Identification of a Gene Located at Chromosome 5q21 that Is Mutated in Colorectal Cancers

1991 • 758 citations

Site-Specific Oligonucleotide Binding Represses Transcription of the Human c- myc Gene in Vitro

1988 • 707 citations

A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1

1987 • 696 citations

Ubiquitous, interspersed repeated sequences in mammalian genomes.

1980 • 568 citations

THE ROLE OF ANTISENSE RNA IN GENE REGULATION

1986 • 456 citations

Selective Inhibition of Leukemia Cell Proliferation by BCR-ABL Antisense Oligodeoxynucleotides

1991 • 353 citations

Intragenic pausing and anti-sense transcription within the murine c-myc locus.

1986 • 326 citations

A novel member of the thyroid/steroid hormone receptor family is encoded by the opposite strand of the rat c-erbA alpha transcriptional unit.

1989 • 316 citations

Solid-phase extraction and determination of dansyl derivatives of unconjugated and acetylated polyamines by reversed-phase liquid chromatography: Improved separation systems for polyamines in cerebrospinal fluid, urine and tissue

1986 • 263 citations

Two erbA homologs encoding proteins with different T3 binding capacities are transcribed from opposite DNA strands of the same genetic locus

1989 • 251 citations

Sequence requirements for premature termination of transcription in the human c-myc gene

1988 • 246 citations

Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase.

1983 • 232 citations

Antisense RNA: its functions and applications in gene regulation — a review

1988 • 230 citations

Modulation of eukaryotic gene expression by complementary RNA or DNA sequences.

1988 • 227 citations

G₁/S Transition in Normal Human T-Lymphocytes Requires the Nuclear Protein Encoded by c-myb

1989 • 226 citations

Human 7SL RNA consists of a 140 nucleotide middle-repetitive sequence inserted in an Alu sequence

1982 • 212 citations

Polyamines Differentially Modulate the Transcription of Growth-associated Genes in Human Colon Carcinoma Cells

1989 • 211 citations

Novel promoter upstream of the human c-myc gene and regulation of c-myc expression in B-cell lymphomas.

1986 • 176 citations

Antisense RNA Directed Against the 3′ Noncoding Region Prevents Dormant mRNA Activation in Mouse Oocytes

1988 • 174 citations

N-myc mRNA Forms an RNA-RNA Duplex with Endogenous Antisense Transcripts

1990 • 173 citations

A nuclease-hypersensitive element of the human c-myc promoter interacts with a transcription initiation factor.

1989 • 148 citations

Inhibition of protooncogene expression by antisense oligodeoxynucleotides: biological and therapeutic implications.

1991 • 140 citations

Techniques for using antisense oligodeoxyribonucleotides to study gene expression

1988 • 130 citations

A transcriptional repressor of c-myc

1989 • 129 citations

Multiple mechanisms for transcriptional regulation of the myc gene family in small-cell lung cancer.

1988 • 127 citations

Control of ColE1 plasmid replication by antisense RNA

1991 • 113 citations

Negative autoregulation of c-myc gene expression is inactivated in transformed cells.

1990 • 112 citations

Negative regulation of the human epsilon-globin gene by transcriptional interference: role of an Alu repetitive element.

1990 • 112 citations

Naturally occurring antisense RNA control — a brief review

1988 • 105 citations

Trans-acting elements modulate expression of the human c-myc gene in Burkitt lymphoma cells.

1986 • 95 citations

Effect of polyamine depletion on c-myc expression in human colon carcinoma cells.

1988 • 92 citations

A Negative Regulatory Element with Properties Similar to Those of Enhancers Is Contained within an Alu Sequence

1989 • 87 citations

Common factor 1 is a transcriptional activator which binds in the c-myc promoter, the skeletal alpha-actin promoter, and the immunoglobulin heavy-chain enhancer.

1991 • 84 citations

Transcription, processing and nuclear transport of a B1 Alu RNA species complementary to an intron of the murine α-fetoprotein gene

1985 • 78 citations

Target sequences for cis-acting regulation within the dual promoter of the human c-myc gene.

1987 • 69 citations

Independent regulation of transcription of the two strands of the c-myc gene.

1987 • 63 citations

Depletion of c-myc with specific antisense sequences reverses the transformed phenotype in ras oncogene-transformed NIH 3T3 cells.

1991 • 61 citations

Characterization of translational-control ribonucleic acid isolated from embryonic chick muscle

1983 • 55 citations

Antisense RNA complementary to 3' coding and noncoding sequences of creatine kinase is a potent inhibitor of translation in vivo.

1989 • 46 citations

Modulation of growth gene expression by selective alteration of polyamines in human colon carcinoma cells

1989 • 40 citations

Expression of the thyroid sodium/iodide symporter in Xenopus laevis oocytes

1989 • 32 citations