The Structural Basis for the Specificity of Epidermal Growth Factor and Heregulin Binding

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Peptide Growth Factors and Their Receptors

1991 • 1,221 citations

Identification of Heregulin, a Specific Activator of p185 ^erbB2

1992 • 963 citations

Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system

1993 • 744 citations

Coexpression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for heregulin.

1994 • 649 citations

ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family

1993 • 612 citations

A neu acquaintance for ErbB3 and ErbB4: A role for receptor heterodimerization in growth signaling

1994 • 601 citations

Neu differentiation factor: A transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit

1992 • 579 citations

An SN2 deprotection of synthetic peptides with a low concentration of hydrofluoric acid in dimethyl sulfide: evidence and application in peptide synthesis

1983 • 545 citations

Isolation of the NeuHER-2 stimulatory ligand: A 44 kd glycoprotein that induces differentiation of mammary tumor cells

1992 • 534 citations

Heregulin induces tyrosine phosphorylation of HER4/p180erbB4

1993 • 445 citations

The type 1 (EGFR-related) family of growth factor receptors and their ligands

1992 • 377 citations

The erbB3 gene product is a receptor for heregulin.

1994 • 361 citations

ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms.

1994 • 273 citations

Cell-type specific interaction of Neu differentiation factor (NDF/heregulin) with Neu/HER-2 suggests complex ligand-receptor relationships.

1993 • 237 citations

Rat epidermal growth factor: complete amino acid sequence

1985 • 132 citations

NDF/heregulin stimulates the phosphorylation of Her3/erbB3

1994 • 65 citations

The role of erbB2 signal transduction pathways in human breast cancer

1993 • 58 citations

Structure-function analysis of synthetic and recombinant derivatives of transforming growth factor alpha.

1988 • 57 citations

Critical functional requirement for the guanidinium group of the arginine 41 side chain of human epidermal growth factor as revealed by mutagenic inactivation and chemical reactivation.

1992 • 52 citations

Solution structure of the epidermal growth factor-like domain of heregulin-alpha, a ligand for p180erbB-4.

1994 • 47 citations

Mutational analysis of leucine 47 in human epidermal growth factor

1991 • 42 citations

Structure-activity relationships of human epidermal growth factor(h-EGF)

1994 • 9 citations