Mutational analysis of leucine 47 in human epidermal growth factor

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity

1962 • 6,970 citations

Epidermal Growth Factor

1979 • 2,964 citations

Structure and Function of Human Amphiregulin: A Member of the Epidermal Growth Factor Family

1989 • 586 citations

Human epidermal growth factor and the proliferation of human fibroblasts

1976 • 403 citations

Epidermal growth factor. Relationship between receptor regulation and mitogenesis in 3T3 cells.

1978 • 324 citations

The role of beta-hydroxyaspartate and adjacent carboxylate residues in the first EGF domain of human factor IX.

1988 • 240 citations

Growth factor control of epidermal growth factor receptor kinase activity via an intramolecular mechanism.

1988 • 98 citations

Nonessentiality of histidine 291 of Rhodospirillum rubrum ribulose-bisphosphate carboxylase/oxygenase as determined by site-directed mutagenesis.

1986 • 71 citations

Cloning of authentic human epidermal growth factor as a bacterial secretory protein and its initial structure-function analysis by site-directed mutagenesis.

1988 • 71 citations

The contribution of the C-terminal undecapeptide sequence of urogastrone-epidermal growth factor to its biological action

1988 • 64 citations

Human epidermal growth factor

1990 • 63 citations

Murine epidermal growth factor: structure and function

1988 • 57 citations

Structure‐function analysis of epidermal growth factor: site directed mutagenesis and nuclear magnetic resonance

1990 • 53 citations

Purification of the epidermal growth factor receptor by tyrosine-Sepharose affinity chromatography

1985 • 50 citations

Structure-function studies of murine epidermal growth factor: expression and site-directed mutagenesis of epidermal growth factor gene

1988 • 46 citations

Biochemical properties of site-directed mutants of human epidermal growth factor: the importance of solvent-exposed hydrophobic residues of the amino-terminal domain in receptor binding

1990 • 44 citations

Transforming Growth Factor α: Mutation of Aspartic Acid 47 and Leucine 48 Results in Different Biological Activities

1988 • 40 citations

Global Modulation of the Epidermal Growth Factor Receptor Is Triggered by Occupancy of Only a Few Receptors

1989 • 40 citations

Conformational characterization of a single-site mutant of murine epidermal growth factor (EGF) by 1H NMR provides evidence that leucine-47 is involved in the interactions with the EGF receptor.

1989 • 35 citations

Analogs of human epidermal growth factor which partially inhibit the growth factor-dependent protein-tyrosine kinase activity of the epidermal growth factor receptor

1990 • 34 citations

Transforming growth factor alpha: mutation of aspartic acid 47 and leucine 48 results in different biological activities.

1988 • 22 citations