Superoxide is an antagonist of anti-inflammatory drugs that inhibit hypochlorous acid production by myeloperoxidase

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

A SPECTROPHOTOMETRIC METHOD FOR MEASURING THE BREAKDOWN OF HYDROGEN PEROXIDE BY CATALASE

1952 • 6,430 citations

Studies on the chlorinating activity of myeloperoxidase.

1976 • 918 citations

Chlorination of Taurine by Human Neutrophils

1982 • 794 citations

The role of superoxide anion generation in phagocytic bactericidal activity. Studies with normal and chronic granulomatous disease leukocytes.

1975 • 705 citations

Molecular basis of chronic granulomatous disease [see comments]

1991 • 290 citations

Assessment of chlorination by human neutrophils

1983 • 285 citations

Chlorohydrin formation from unsaturated fatty acids reacted with hypochlorous acid

1992 • 255 citations

Molecular basis of chronic granulomatous disease [see comments]

1991 • 210 citations

Mechanism of inhibition of myeloperoxidase by anti-inflammatory drugs

1991 • 187 citations

The Inhibition of Polymorphonuclear Leukocyte Cytotoxicity by Dapsone

1978 • 182 citations

Superoxide modulates the activity of myeloperoxidase and optimizes the production of hypochlorous acid

1988 • 177 citations

Assay of the human leukocyte enzymes myeloperoxidase and eosinophil peroxidase

1990 • 169 citations

Myeloperoxidase of the leukocyte of normal blood. I. Reaction of myeloperoxidase with hydrogen peroxide

1970 • 145 citations

Oxidative damage to fibronectin

1991 • 139 citations

Selective labilization of specific granules in polymorphonuclear leukocytes by phorbol myristate acetate.

1974 • 118 citations

Inhibition of the human leukocyte enzymes myeloperoxidase and eosinophil peroxidase by dapsone

1992 • 100 citations

Myeloperoxidase Deficiency

1988 • 99 citations

Human myeloperoxidase activity is inhibited in vitro by quercetin. Comparison with three related compounds

1988 • 98 citations

Inhibition of the myeloperoxidase-H2O2-Cl− system of neutrophils by indomethacin and other non-steroidal anti-inflammatory drugs

1991 • 81 citations

Mechanisms by which clofazimine and dapsone inhibit the myeloperoxidase system

1991 • 76 citations

Inhibition of myeloperoxidase by salicylhydroxamic acid

1989 • 73 citations

Oxygen Radicals: Systemic Events and Disease Processes

1991 • 69 citations

Influence of superoxide on myeloperoxidase kinetics measured with a hydrogen peroxide electrode

1989 • 66 citations

Autocatalytic inactivation of cytochrome p-450 and chloroperoxidase by 1-aminobenzotriazole and other aryne precursors

1984 • 66 citations

Exocytosis by Neutrophils

1984 • 65 citations

In vitro and in vivo effects of dapsone on neutrophil and lymphocyte functions in normal individuals and patients with lepromatous leprosy

1981 • 64 citations

Mechanism of inactivation of myeloperoxidase by propylthiouracil

1990 • 62 citations

Oxidation of hydroquinone by myeloperoxidase. Mechanism of stimulation by benzoquinone.

1992 • 60 citations

2 Neutrophil Oxidants: Production and Reactions

2015 • 51 citations

Superoxide enhances hypochlorous acid production by stimulated human neutrophils

1990 • 46 citations

Iodination by stimulated human neutrophils. Studies on its stoichiometry, subcellular localization and relevance to microbial killing

1983 • 40 citations

The role of hydroxyl radicals in irreversible inactivation of lactoperoxidase by excess H2O2

1987 • 39 citations

Interaction of myeloperoxidase with diclofenac

1990 • 39 citations

The effect of d-penicillamine on myeloperoxidase: formation of Compound III and inhibition of the chlorinating activity

1987 • 30 citations

Dermatitis herpetiformis: Effects of sulfones and sulfonamides on neutrophil myeloperoxidase-mediated iodination and cytotoxicity

1984 • 28 citations

Oxidative metabolism of amsacrine by the neutrophil enzyme myeloperoxidase

1992 • 22 citations