Evidence for a High Affinity, Saturable, Prenylation-dependent p21 Binding Site in Plasma Membranes

PROTEIN PRENYLATION: Molecular Mechanisms and Functional Consequences

1996 • 1,977 citations

All ras proteins are polyisoprenylated but only some are palmitoylated

1989 • 1,806 citations

A Manual of Methods for Baculovirus Vectors and Insect Cell Culture Procedures.

1987 • 1,703 citations

FUNCTION AND REGULATION OF RAS

1993 • 1,161 citations

Analysis of serum insulin-like growth factor binding proteins using Western blotting: Use of the method for titration of the binding proteins and competitive binding studies

1986 • 1,158 citations

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

1990 • 1,049 citations

Co-purification and Direct Interaction of Ras with Caveolin, an Integral Membrane Protein of Caveolae Microdomains

1996 • 1,006 citations

Quantitative Analysis of the Complex between p21 and the Ras-binding Domain of the Human Raf-1 Protein Kinase

1995 • 348 citations

Protein Prenylation: a Mediator of Protein-Protein Interactions

1993 • 346 citations

Purification and properties of a palmitoyl-protein thioesterase that cleaves palmitate from H-Ras.

1993 • 344 citations

Lamin B constitutes an intermediate filament attachment site at the nuclear envelope.

1987 • 306 citations

Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein.

1992 • 180 citations

Methods in neurotransmitter receptor analysis

1991 • 178 citations

The small GTP-binding proteins in the cytosol of insulin-secreting cells are complexed to GDP dissociation inhibitor proteins.

1992 • 174 citations

N-terminally myristoylated Ras proteins require palmitoylation or a polybasic domain for plasma membrane localization.

1994 • 165 citations

[55] General procedures for separating lipid components of tissue

1957 • 131 citations

Inhibition of DNA synthesis in cultures of 3T3 cells by isolated surface membranes.

1977 • 123 citations

Binding of prenylated and polybasic peptides to membranes: affinities and intervesicle exchange

1995 • 113 citations

Prenylation of Ras proteins is required for efficient hSOS1-promoted guanine nucleotide exchange.

1994 • 110 citations

Identifying the recognition unit for G protein methylation

1991 • 102 citations

Ras (CXXX) and Rab (CC/CXC) prenylation signal sequences are unique and functionally distinct.

1992 • 72 citations

In Vitro Assay and Characterization of the Farnesylation-dependent Prelamin A Endoprotease

1997 • 70 citations

Effect of Insulin on Farnesyltransferase Activity in 3T3-L1 Adipocytes

1996 • 67 citations

Expression and characterization of the Ha-ras p21 protein produced at high levels in the insect/baculovirus system

1989 • 49 citations

Oncogene v-jun modulates DNA replication.

1990 • 30 citations

[2] Purification of baculovirus-expressed recombinant ras and rap proteins

1995 • 29 citations

5′-Nucleotidase activity and substrate affinity in digenetic trematodes

1985 • 3 citations