Lipid Modulation and Systemic Inflammation

Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial

1999 • 3,818 citations

EFFECTS OF CHANGES IN FAT, FISH, AND FIBRE INTAKES ON DEATH AND MYOCARDIAL REINFARCTION: DIET AND REINFARCTION TRIAL (DART)

1989 • 2,639 citations

Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease

1994 • 2,133 citations

The Effect of Dietary Supplementation with n—3 Polyunsaturated Fatty Acids on the Synthesis of Interleukin-1 and Tumor Necrosis Factor by Mononuclear Cells

1989 • 1,951 citations

Effect of Dietary Enrichment with Eicosapentaenoic and Docosahexaenoic Acids on in Vitro Neutrophil and Monocyte Leukotriene Generation and Neutrophil Function

1985 • 1,344 citations

Fish Consumption and Risk of Sudden Cardiac Death

1998 • 1,002 citations

Dietary Intake and Cell Membrane Levels of Long-Chain n-3 Polyunsaturated Fatty Acids and the Risk of Primary Cardiac Arrest

1995 • 911 citations

Effect of an Enteric-Coated Fish-Oil Preparation on Relapses in Crohn's Disease

1996 • 780 citations

Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in patients with acute respiratory distress syndrome

1999 • 755 citations

心筋梗塞後のn-3多価不飽和脂肪酸とビタミンEの食事補給:GISSI-Prevenzione試験の結果

1999 • 704 citations

Oral (n-3) Fatty Acid Supplementation Suppresses Cytokine Production and Lymphocyte Proliferation: Comparison between Young and Older Women

1991 • 704 citations

Fish-Oil Fatty Acid Supplementation in Active Rheumatoid Arthritis

1987 • 544 citations

Immunonutrition in the critically ill: A systematic review of clinical outcome

1999 • 500 citations

Enteral Nutritional Supplementation With Key Nutrients in Patients With Critical Illness and Cancer

1999 • 499 citations

The Effect of Dietary ω-3 Fatty Acids on Coronary Atherosclerosis

1999 • 497 citations

The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells.

1994 • 467 citations

N-3 polyunsaturated fatty acid regulation of hepatic gene transcription

2008 • 429 citations

In Vivo Indexes of Platelet and Vascular Function during Fish-Oil Administration in Patients with Atherosclerosis

1986 • 424 citations

EFFECTS OF MANIPULATION OF DIETARY FATTY ACIDS ON CLINICAL MANIFESTATIONS OF RHEUMATOID ARTHRITIS

1985 • 420 citations

Dietary Supplementation with Fish Oil in Ulcerative Colitis

1992 • 405 citations

Prevention of Sudden Cardiac Death by Dietary Pure ω-3 Polyunsaturated Fatty Acids in Dogs

1999 • 404 citations

A DOUBLE-BLIND, RANDOMISED, PLACEBO-CONTROLLED TRIAL OF FISH OIL IN PSORIASIS

1988 • 330 citations

Dietary enrichment with the polyunsaturated fatty acid eicosapentaenoic acid prevents proteinuria and prolongs survival in NZB x NZW F1 mice.

1981 • 328 citations

n-3 Polyunsaturated Fatty Acids and Cytokine Production in Health and Disease

1997 • 326 citations

Dietary Polyunsaturated Fatty Acid Regulation of Gene Transcription

1994 • 305 citations

A fish oil diet rich in eicosapentaenoic acid reduces cyclooxygenase metabolites, and suppresses lupus in MRL-lpr mice.

1985 • 304 citations

ORAL CONTRACEPTIVE USE AND MALIGNANCIES OF THE GENITAL TRACT

1988 • 292 citations

Fish Oils Inhibit Endothelial Cell Production of Platelet-Derived Growth Factor-Like Protein

1988 • 274 citations

Reduced asthma symptoms with n-3 fatty acid ingestion are related to 5-series leukotriene production

1997 • 271 citations

Effect of dietary supplementation with n-3 fatty acids on coronary artery bypass graft patency

1996 • 263 citations

Prevention of ischemia-induced ventricular fibrillation by omega 3 fatty acids.

1994 • 254 citations

Relative effects of dietary saturated, monounsaturated, and polyunsaturated fatty acids on cardiac arrhythmias in rats

1993 • 252 citations

Fatty acid intake and Kupffer cell function: fish oil alters eicosanoid and monokine production to endotoxin stimulation.

1988 • 248 citations

The Importance of Lipid Type in the Diet after Burn Injury

1986 • 239 citations

Dietary supplementation with n-3 fatty acids suppresses interleukin-2 production and mononuclear cell proliferation

1993 • 236 citations

Antiarrhythmic Effects of Polyunsaturated Fatty Acids

1996 • 230 citations

Dietary fish oil modulates macrophage fatty acids and decreases arthritis susceptibility in mice.

1985 • 215 citations

Modulation of dihydropyridine-sensitive calcium channels in heart cells by fish oil fatty acids.

1992 • 211 citations

Evidence that free polyunsaturated fatty acids modify Na+ channels by directly binding to the channel proteins.

1996 • 185 citations

A double-blind, randomized placebo controlled trial on fish oil in psoriasis

1988 • 180 citations

A double-blind controlled trial of long chain n-3 polyunsaturated fatty acids in the treatment of multiple sclerosis.

1989 • 178 citations

Effects of Dietary Supplementation of Fish Oil on Neutrophil and Epidermal Fatty Acids

1986 • 166 citations

Early Enteral Feeding in Postsurgical Cancer Patients

1996 • 162 citations

Effects of dietary enrichment with eicosapentaenoic acid upon autoimmune nephritis in female NZBXNZW/F₁ MICE

1983 • 159 citations

Control of endothelial leukocyte adhesion molecules by fatty acids

1996 • 158 citations

Immunoregulation by leukotrienes and other lipoxygenase metabolites

1985 • 147 citations

Regulation of gene transcription by polyunsaturated fatty acids

1993 • 139 citations

Long-Term Treatment with Eicosapentaenoic Acid Augments Both Nitric Oxide-Mediated and Non-Nitric Oxide-Mediated Endothelium-Dependent Forearm Vasodilatation in Patients with Coronary Artery Disease

1999 • 136 citations

Immunoregulation by Parenteral Lipids: Impact of the n‐3 to n‐6 Fatty Acid Ratio

1994 • 136 citations

Dietary omega-3 fatty acids lower levels of platelet-derived growth factor mRNA in human mononuclear cells

1993 • 136 citations

Treatment of Ulcerative Colitis with Fish Oil n-3-ω-Fatty Acid

1990 • 136 citations

The effects of N-3 polyunsaturated fatty acids on the generation of platelet-activating factor-acether by human monocytes.

1987 • 135 citations

Fish oil decreases natural resistance of mice to infection with Salmonella typhimurium

1992 • 135 citations

Prostaglandin E precursor fatty acids inhibit human IL-2 production by a prostaglandin E-independent mechanism

1990 • 134 citations

Effects of dietary fish oil on ventricular premature complexes

1995 • 132 citations

Comparative efficacy of n−3 and n−6 polyunsaturated fatty acids in modulating ventricular fibrillation threshold in marmoset monkeys

1993 • 129 citations

Dietary ω-3, ω-6, and ω-9 Unsaturated Fatty Acids and Growth Factor and Cytokine Gene Expression in Unstimulated and Stimulated Monocytes

1999 • 120 citations

Omega 3 polyunsaturated fatty acid modulates dihydropyridine effects on L-type Ca2+ channels, cytosolic Ca2+, and contraction in adult rat cardiac myocytes.

1994 • 119 citations

Effects of eicosapentaenoic and gamma-linolenic acid on lung permeability and alveolar macrophage eicosanoid synthesis in endotoxic rats

1997 • 108 citations

Enhanced survival to endotoxin in guinea pigs fed IV fish oil emulsion

1988 • 108 citations

Endotoxin challenge after menhaden oil diet: effects on survival of guinea pigs

1989 • 108 citations

Dietary Fish Oil Reduces Survival and Impairs Bacterial Clearance in C3H/Hen Mice Challenged with Listeria Monocytogenes

1997 • 107 citations

Dietary Fish-Oil Supplementation in Experimental Gram-Negative Infection and in Cerebral Malaria in Mice

1992 • 106 citations

Dietary fat and colon cancer: modulating effect of types and amount of dietary fat on ras-p21 function during promotion and progression stages of colon cancer.

1997 • 100 citations

Dietary Omega-3 Fatty Acids Decrease Mortality and Kupffer Cell Prostaglandin E2 Production in a Rat Model of Chronic Sepsis

1991 • 98 citations

Nutritional Control of Rat Liver Fatty Acid Synthase and S14 mRNA Abundance

1990 • 98 citations

Beneficial effect of eicosapentaenoic and docosahexaenoic acids in the management of systemic lupus erythematosus and its relationship to the cytokine network

1994 • 93 citations

Dietary marine lipids suppress continuous expression of interleukin‐1β gene transcription¹

1996 • 84 citations

Clinical Applications of Fish Oils

1988 • 82 citations

Omega-3 Polyunsaturated Fatty Acids: A Potential New Treatment of Immune Renal Disease

1991 • 79 citations

Effects of Intravenous ω‐3 and ω‐6 Fat Emulsion on Cytokine Production and Delayed Type Hypersensitivity in Burned Rats Receiving Total Parenteral Nutrition

1998 • 77 citations

Polyunsaturated fatty acid regulation of hepatic gene transcription

1996 • 76 citations

The Role of Fatty Acids in Gene Expression: Health Implications

1996 • 75 citations

Effects of different polunsaturated fatty acids on growth‐related early gene expression and cell growth

1996 • 75 citations

Effect of short-term enteral feeding with eicosapentaenoic and γ-linolenic acids on alveolar macrophage eicosanoid synthesis and bactericidal function in rats

1999 • 74 citations

n-3 versus n-6 polyunsaturated fatty acids in critical illness

1998 • 69 citations

PROLONGATION OF SKIN ALLOGRAFTS IN RATS BY TREATMENT WITH LINOLEIC ACID

1974 • 68 citations

Effect of a Fish-Oil-Supplemented Diet on Inflammation and Immunological Processes in Rats

1987 • 63 citations

Influence of Dietary Fatty Acids on Cytokine Production and Its Clinical Implications

1993 • 61 citations

Effect of Dietary (n-3) and (n-6) Fatty Acids on In Vivo Pulmonary Bacterial Clearance by Neonatal Rabbits

1991 • 59 citations

Effect of Different Combinations of Dietary Additives on Bacterial Translocation and Survival in Gut‐Derived Sepsis

1995 • 58 citations

Influence of butter and of corn, coconut and fish oils on the effects of recombinant human tumour necrosis factor-α in rats

1993 • 57 citations

Modulation of Cytokine Production by Dietary Polyunsaturated Fatty Acids

1992 • 54 citations

Select dietary fatty acids attenuate cardiopulmonary dysfunction during acute lung injury in pigs

1995 • 53 citations

Alteration of n-3 fatty acid composition in lung tissue after short-term infusion of fish oil emulsion attenuates inflammatory vascular reaction

1996 • 53 citations

ESSENTIAL FATTY ACIDS INFLUENCE SURVIVAL IN SEPSIS

1993 • 52 citations

The Effect of Dietary Fatty Acids on Response to Pseudomonas Infection in Burned Mice

1990 • 47 citations

Effects of a Fish Oil Diet on Pigs' Cardiopulmonary Response to Bacteremia

1991 • 43 citations

Life Span is Shortened in BHE/cdb Rats Fed a Diet Containing 9% Menhaden Oil and 1% Corn Oil

1992 • 38 citations

Short‐Term Dietary Lipid Manipulation Does Not Affect Survival in Two Models of Murine Sepsis

1992 • 36 citations

Composition of Fat in Enteral Diets Can Influence Outcome in Experimental Peritonitis

1991 • 34 citations

Dietary marine lipid does not alter susceptibility of (NZBxNZW) F1 mice to pathogenic microorganisms

1989 • 32 citations

Short-term TPN containing n-3 fatty acids ameliorate lactic acidosis induced by endotoxin in guinea pigs

1990 • 28 citations

Potential of Diet Therapy on Murine AIDS ,

1992 • 28 citations

Essential fatty acids are antagonists of the leukotriene B4 receptor

1995 • 27 citations

Effect of dietary linolenic acid on endotoxin-induced thromboxane and prostacyclin production by equine peritoneal macrophages.

1989 • 25 citations

Essential fatty acid deficient rats: a new model for evaluating arachidonate metabolism in shock.

1981 • 20 citations

Effects of parenteral infusion with fish-oil or safflower-oil emulsion on hepatic lipids, plasma amino acids, and inflammatory mediators in septic rats

2000 • 19 citations

DIETARY IMMUNOREGULATION OF TRANSFUSION-INDUCED IMMUNOSUPPRESSION

1988 • 18 citations

n-3 polyunsaturated fatty acids as pharmacologic agents: A fishy tale?

1997 • 17 citations

DIETARY SOURCE OF Ω-3 FATTY ACIDS AFFECTS ENDOTOXIN-INDUCED PERITONEAL MACROPHAGE TUMOR NECROSIS FACTOR AND EICOSANOID SYNTHESIS

1994 • 16 citations

AUGMENTATION OF DONOR-SPECIFIC TRANSFUSION AND CYCLOSPORINE EFFECTS WITH DIETARY LINOLEIC ACID

1989 • 9 citations

Enriched feeding formula and immune responses and outcome after Listeria monocytogenes challenge in mice.

1992 • 9 citations

PERINATAL NUTRITION ENRICHED WITH OMEGA-3 POLYUNSATURATED FATTY ACIDS ATTENUATES ENDOTOXIC SHOCK IN NEWBORN RATS

1996 • 8 citations

EFFECTS OF DIETARY α- AND λ-LINOLENIC ACIDS ON LIVER FATTY ACIDS, LIPID METABOLISM, AND SURVIVAL IN SEPSIS

1995 • 8 citations

EFFECTS OF ENTERAL FEEDING PRODUCTS ON SURVIVAL FROM ESCHERICHIA COLI PERITONITIS

1994 • 7 citations

Long-chain n-3 polyunsaturated fatty acids and coronary heart disease

2000 • 5 citations

Dietary enrichment with omega-3 fatty acids partially protects against lipopolysaccharide-induced atrial depression in rats.

1992 • 2 citations

Deleted Work

1955 • 0 citations