Semaphorin III Can Induce Death in Sensory Neurons

The Molecular Biology of Axon Guidance

1996 • 3,246 citations

Programmed Cell Death and the Control of Cell Survival: Lessons from the Nervous System

1993 • 1,470 citations

Neuropilin Is a Semaphorin III Receptor

1997 • 1,166 citations

Collapsin: A protein in brain that induces the collapse and paralysis of neuronal growth cones

1993 • 1,146 citations

Neuropilin Is a Receptor for the Axonal Chemorepellent Semaphorin III

1997 • 1,131 citations

The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules

1993 • 930 citations

Conversion of Neuronal Growth Cone Responses from Repulsion to Attraction by Cyclic Nucleotides

1998 • 784 citations

Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33

1995 • 687 citations

A License to Kill

1996 • 649 citations

Neuropilin–Semaphorin III/D-Mediated Chemorepulsive Signals Play a Crucial Role in Peripheral Nerve Projection in Mice

1997 • 647 citations

Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.

1994 • 617 citations

Neuronal Cell Death

1998 • 593 citations

Chapter 9 The End of the (Cell) Line: Methods for the Study of Apoptosis in Vitro

1995 • 569 citations

The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons

1995 • 566 citations

Disruption of Semaphorin III/D Gene Causes Severe Abnormality in Peripheral Nerve Projection

1997 • 517 citations

Sernaphorin III can function as a selective chemorepellent to pattern sensory projections in the spinal cord

1995 • 492 citations

Neuronal death in the spinal ganglia of the chick embryo and its reduction by nerve growth factor

1981 • 407 citations

Bax Deletion Further Orders the Cell Death Pathway in Cerebellar Granule Cells and Suggests a Caspase-independent Pathway to Cell Death

1997 • 390 citations

Rac1 Mediates Collapsin-1-Induced Growth Cone Collapse

1997 • 384 citations

Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension

1995 • 352 citations

Expression of the Gene Encoding the Chemorepellent Semaphorin III Is Induced in the Fibroblast Component of Neural Scar Tissue Formed Following Injuries of Adult But Not Neonatal CNS

1999 • 308 citations

Thrombin Induces Apoptosis in Cultured Neurons and Astrocytes via a Pathway Requiring Tyrosine Kinase and RhoA Activities

1997 • 303 citations

Development of sympathetic neurons in compartmentalized cultures

1982 • 303 citations

Developmentally regulated expression of a cell surface protein, neuropilin, in the mouse nervous system

1996 • 292 citations

Protocols for Neural Cell Culture

1993 • 251 citations

Thrombin causes neurite retraction in neuronal cells through activation of cell surface receptors

1992 • 245 citations

Development of sympathetic neurons in compartmentalized cultures

1982 • 239 citations

Expression of the UNC-5 guidance receptor in the touch neurons of C. elegans steers their axons dorsally

1993 • 237 citations

Semaphorins A and E act as antagonists of neuropilin-1 and agonists of neuropilin-2 receptors

1998 • 232 citations

Secreted Chick Semaphorins Bind Recombinant Neuropilin with Similar Affinities but Bind Different Subsets of Neurons In Situ

1997 • 191 citations

Anatomy of rat semaphorin III collapsin‐1 mRNA expression and relationship to developing nerve tracts during neuroembryogenesis

1996 • 185 citations

Efficient Nuclear Targeting of Granzyme B and the Nuclear Consequences of Apoptosis Induced by Granzyme B and Perforin Are Caspase-dependent, but Cell Death Is Caspase-independent

1998 • 166 citations

Bcl-2 Prevents Caspase-independent Cell Death

1998 • 162 citations

The guidance molecule Semaphorin III is expressed in regions of spinal cord and periphery avoided by growing sensory axons

1995 • 162 citations

Anatomy of rat semaphorin III collapsin-1 mRNA expression and relationship to developing nerve tracts during neuroembryogenesis

1996 • 158 citations

Neurites Can Remain Viable after Destruction of the Neuronal Soma by Programmed Cell Death (Apoptosis)

1994 • 154 citations

The Sensory Innervation of the Mouse Spinal Cord May Be Patterned by Differential Expression of and Differential Responsiveness to Semaphorins

1996 • 153 citations

A 70 Amino Acid Region within the Semaphorin Domain Activates Specific Cellular Response of Semaphorin Family Members

1997 • 145 citations

The Distribution of Collapsin-1 mRNA in the Developing Chick Nervous System

1996 • 139 citations

Thrombin Perturbs Neurite Outgrowth and Induces Apoptotic Cell Death in Enriched Chick Spinal Motoneuron Cultures through Caspase Activation

1998 • 131 citations

Anatomical distribution of the chemorepellent semaphorin III/collapsin-1 in the adult rat and human brain: Predominant expression in structures of the olfactory-hippocampal pathway and the motor system

1998 • 121 citations

Transition from Caspase-dependent to Caspase-independent Mechanisms at the Onset of Apoptotic Execution

1998 • 120 citations

Differential patterns of semaphorin expression in the developing rat brain

1998 • 118 citations

A sensory axon repellent secreted from ventral spinal cord explants is neutralized by antibodies raised against collapsin-1

1997 • 114 citations

Purification and characterization of a trophic factor for embryonic peripheral neurons: Comparison with fibroblast growth factors

1990 • 111 citations

The death domain motif found in Fas (Apo‐1) and TNF receptor is present in proteins involved in apoptosis and axonal guidance

1995 • 109 citations

An ankyrin-related gene (unc-44) is necessary for proper axonal guidance in Caenorhabditis elegans.

1995 • 106 citations

Dorsal root ganglion cell death and surviving cell numbers in relation to the development of sensory innervation in the rat hindlimb

1994 • 105 citations

GAP-43 expression in developing cutaneous and muscle nerves in the rat hindlimb

1991 • 104 citations

Semaphorins: mediators of repulsive growth cone guidance

1996 • 103 citations

GAP-43 expression in the developing rat lumbar spinal cord

1991 • 99 citations

Ventral spinal cord inhibition of neurite outgrowth from embryonic rat dorsal root ganglia

1993 • 99 citations

Development of Drosophila wing sensory neurons in mutants with missing or modified cell surface molecules

1993 • 62 citations

Trigeminal Ganglion Axons Are Repelled By Their Presumptive Targets

1998 • 44 citations

Construction and Use of Compartmented Cultures

1997 • 6 citations

Primary Cell Cultures of Peripheral and Central Neurons and Glia

1997 • 4 citations