Back to search

Expression of the Gene Encoding the Chemorepellent Semaphorin III Is Induced in the Fibroblast Component of Neural Scar Tissue Formed Following Injuries of Adult But Not Neonatal CNS

Data up to Jan 2025

Published1999
Citations308
References134

Total Citations Per Year

Abstract

References (134)

The Molecular Biology of Axon Guidance

1996 • 3,246 citations

Atlas of tumor pathology

1968 • 3,075 citations

Degeneration and Regeneration of the Nervous System.

1929 • 2,924 citations

Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor

1998 • 2,440 citations

— Tumors of the Central Nervous System

2013 • 1,787 citations

Axonal Elongation into Peripheral Nervous System "Bridges" After Central Nervous System Injury in Adult Rats

1981 • 1,679 citations

The Heterogeneity of Mononuclear Phagocytes in Lymphoid Organs: Distinct Macrophage Subpopulations in Rat Recognized by Monoclonal Antibodies ED1, ED2 and ED3

1985 • 1,605 citations

Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes

1991 • 1,171 citations

Neuropilin Is a Semaphorin III Receptor

1997 • 1,166 citations

A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin-labelled cRNA probes

1993 • 1,166 citations

Collapsin: A protein in brain that induces the collapse and paralysis of neuronal growth cones

1993 • 1,146 citations

Neuropilin Is a Receptor for the Axonal Chemorepellent Semaphorin III

1997 • 1,131 citations

A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration

1994 • 1,068 citations

The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules

1993 • 930 citations

Axons from CNS neurones regenerate into PNS grafts

1980 • 928 citations

Repair of Adult Rat Corticospinal Tract by Transplants of Olfactory Ensheathing Cells

1997 • 879 citations

Two membrane protein fractions from rat central myelin with inhibitory properties for neurite growth and fibroblast spreading.

1988 • 876 citations

Development of oligodendrocytes and Schwann cells studied with a monoclonal antibody against galactocerebroside.

1982 • 842 citations

Cell-type-specific markers for distinguishing and studying neurons and the major classes of glial cells in culture

1979 • 805 citations

Sulfated proteoglycans in astroglial barriers inhibit neurite outgrowth in vitro

1990 • 775 citations

Spinal Cord Repair in Adult Paraplegic Rats: Partial Restoration of Hind Limb Function

1996 • 764 citations

Regeneration of adult axons in white matter tracts of the central nervous system

1997 • 747 citations

Long-Distance Axonal Regeneration in the Transected Adult Rat Spinal Cord Is Promoted by Olfactory Ensheathing Glia Transplants

1998 • 711 citations

Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33

1995 • 687 citations

Two subsets of rat T lymphocytes defined with monoclonal antibodies

1980 • 678 citations

Neuropilin-2, a Novel Member of the Neuropilin Family, Is a High Affinity Receptor for the Semaphorins Sema E and Sema IV but Not Sema III

1997 • 650 citations

Neuropilin–Semaphorin III/D-Mediated Chemorepulsive Signals Play a Crucial Role in Peripheral Nerve Projection in Mice

1997 • 647 citations

Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3.

1986 • 602 citations

Molecular heterogeneity of basal laminae: isoforms of laminin and collagen IV at the neuromuscular junction and elsewhere.

1990 • 588 citations

Semaphorin III is needed for normal patterning and growth of nerves, bones and heart

1996 • 570 citations

Inhibitors of Neurite Growth

1993 • 545 citations

[46] Fibronectin: Purification, immunochemical properties, and biological activities

1982 • 542 citations

Disruption of Semaphorin III/D Gene Causes Severe Abnormality in Peripheral Nerve Projection

1997 • 517 citations

Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion

1993 • 517 citations

Sernaphorin III can function as a selective chemorepellent to pattern sensory projections in the spinal cord

1995 • 492 citations

Plexin A Is a Neuronal Semaphorin Receptor that Controls Axon Guidance

1998 • 456 citations

A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. Differential reactivity with subsets of immature and mature T lymphocytes.

1989 • 455 citations

THE FIBROBLAST AND WOUND REPAIR

1968 • 444 citations

Increased expression of the NG2 chondroitin-sulfate proteoglycan after brain injury

1994 • 395 citations

Monoclonal antibodies specific for vimentin.

1984 • 394 citations

Inhibition of neurite outgrowth on astroglial scars in vitro

1990 • 374 citations

Fasciclin IV: Sequence, expression, and function during growth cone guidance in the grasshopper embryo

1992 • 369 citations

Mouse monoclonal antibodies against rat major histocompatibility antigens. Two Ia antigens and expression of Ia and class I antigens in rat thymus

1982 • 364 citations

Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension

1995 • 352 citations

Neuropilin-2 Is a Receptor for Semaphorin IV Insight into the Structural Basis of Receptor Function and Specificity

1998 • 352 citations

Neuropilin-1 Is a Placenta Growth Factor-2 Receptor

1998 • 344 citations

Semaphorins act as attractive and repulsive guidance signals during the development of cortical projections

1998 • 340 citations

Degeneration & regeneration of the nervous system

1928 • 306 citations

Maturation of astrocytes in vitro alters the extent and molecular basis of neurite outgrowth

1990 • 299 citations

Enhanced expression of the developmentally regulated extracellular matrix molecule tenascin following adult brain injury.

1992 • 297 citations

Developmentally regulated expression of a cell surface protein, neuropilin, in the mouse nervous system

1996 • 292 citations

Deposition of Scar Tissue in the Central Nervous System

1983 • 285 citations

Semaphorin–Neuropilin Interactions Underlying Sympathetic Axon Responses to Class III Semaphorins

1998 • 279 citations

Biology of Dermal Wound Repair

1993 • 266 citations

Tumor Necrosis Factor-α Regulates Expression of Vascular Endothelial Growth Factor Receptor-2 and of Its Co-receptor Neuropilin-1 in Human Vascular Endothelial Cells

1998 • 262 citations

Patterning of Cortical Efferent Projections by Semaphorin-Neuropilin Interactions

1998 • 262 citations

Putative Inhibitory Extracellular Matrix Molecules at the Dorsal Root Entry Zone of the Spinal Cord during Development and after Root and Sciatic Nerve Lesions

1993 • 252 citations

Motor Axon Subpopulations Respond Differentially to the Chemorepellents Netrin-1 and Semaphorin D

1997 • 237 citations

A Poxvirus-Encoded Semaphorin Induces Cytokine Production from Monocytes and Binds to a Novel Cellular Semaphorin Receptor, VESPR

1998 • 234 citations

A family of molecules related to collapsin in the embryonic chick nervous system

1995 • 225 citations

Astrocyte-specific protein and radial glia in the cerebral cortex of newborn rat

1974 • 208 citations

Semaphorins III and IV repel hippocampal axons via two distinct receptors

1998 • 192 citations

Secreted Chick Semaphorins Bind Recombinant Neuropilin with Similar Affinities but Bind Different Subsets of Neurons In Situ

1997 • 191 citations

Anatomy of rat semaphorin III collapsin‐1 mRNA expression and relationship to developing nerve tracts during neuroembryogenesis

1996 • 185 citations

Evidence for a Role of the Chemorepellent Semaphorin III and Its Receptor Neuropilin-1 in the Regeneration of Primary Olfactory Axons

1998 • 184 citations

Regrowth of Severed Axons in the Neonatal Central Nervous System: Establishment of Normal Connections

1979 • 182 citations

Maggot's hair and bug's eye: Role of cell interactions and intrinsic factors in cell fate specification

1995 • 180 citations

Reactivity of a panel of neurofilament antibodies on phosphorylated and dephosphorylated neurofilaments.

1986 • 179 citations

Wound closure: evidence of cooperation between fibroblasts and collagen matrix

1988 • 178 citations

Affinity‐Purified Anti‐B‐50 Protein Antibody: Interference with the Function of the Phosphoprotein B‐50 in Synaptic Plasma Membranes

1983 • 173 citations

The guidance molecule Semaphorin III is expressed in regions of spinal cord and periphery avoided by growing sensory axons

1995 • 162 citations

Reactive astrocytes--a review.

1990 • 162 citations

Anatomy of rat semaphorin III collapsin-1 mRNA expression and relationship to developing nerve tracts during neuroembryogenesis

1996 • 158 citations

The Sensory Innervation of the Mouse Spinal Cord May Be Patterned by Differential Expression of and Differential Responsiveness to Semaphorins

1996 • 153 citations

Meningeal cells organize the superficial glia limitans of the cerebellum and produce components of both the interstitial matrix and the basement membrane

1994 • 151 citations

Fetal cell grafts into resection and contusion/compression injuries of the rat and cat spinal cord

1992 • 147 citations

Neurons of the olfactory epithelium in adult rats contain vimentin

1986 • 146 citations

The Distribution of Collapsin-1 mRNA in the Developing Chick Nervous System

1996 • 139 citations

Semaphorin III can repulse and inhibit adult sensory afferents in vivo

1997 • 139 citations

Neuroplasticity in the rearrangement of olfactory tract fibers after neonatal transection in hamsters

1976 • 136 citations

A Role for Collapsin-1 in Olfactory and Cranial Sensory Axon Guidance

1997 • 135 citations

A Septum-Derived Chemorepulsive Factor for Migrating Olfactory Interneuron Precursors

1996 • 128 citations

Anatomical distribution of the chemorepellent semaphorin III/collapsin-1 in the adult rat and human brain: Predominant expression in structures of the olfactory-hippocampal pathway and the motor system

1998 • 121 citations

Characterization of a Neurite Outgrowth Inhibitor Expressed After CNS Injury

1993 • 118 citations

Regional Heterogeneity in the Response of Astrocytes following Traumatic Brain Injury in the Adult Rat

1996 • 116 citations

A sensory axon repellent secreted from ventral spinal cord explants is neutralized by antibodies raised against collapsin-1

1997 • 114 citations

VEGF mRNA Induction Correlates With Changes in the Vascular Architecture Upon Spinal Cord Damage in the Rat

1997 • 113 citations

The response of the cerebral hemisphere of the rat to injury. II. The neonatal rat

1990 • 112 citations

Human Semaphorin K1 Is Glycosylphosphatidylinositol-linked and Defines a New Subfamily of Viral-related Semaphorins

1998 • 105 citations

Regulation of Semaphorin III/Collapsin-1 Gene Expression during Peripheral Nerve Regeneration

1998 • 104 citations

Semaphorins: mediators of repulsive growth cone guidance

1996 • 103 citations

An Ultrastructural and Immunocytochemical Analysis of Leptomeningeal and Meningioma Cultures

1986 • 101 citations

Three morphologically distinct types of interface develop between adult host and fetal brain transplants: Implications for scar formation in the adult central nervous system

1986 • 100 citations

The response of the cerebral hemisphere of the rat to injury. I. The mature rat

1990 • 91 citations

Tenascin-C expression and axonal sprouting following injury to the spinal dorsal columns in the adult rat

1997 • 89 citations

Lesion-induced sprouting of commissural/associational axons and induction of GAP-43 mRNA in hilar and CA3 pyramidal neurons in the hippocampus are diminished in aged rats

1995 • 82 citations

Interactions between meningeal cells and astrocytes in vivo and in vitro

1991 • 81 citations

Reactive astrocytes involved in the formation of lesional scars differ in the mediobasal hypothalamus and in other forebrain regions

1993 • 81 citations

Chondroitin Sulfate Proteoglycan and Tenascin in the Wounded Adult Mouse NeostriatumIn Vitro: Dopamine Neuron Attachment and Process Outgrowth

1996 • 77 citations

Injured neurons in the olfactory bulb of the adult rat grow axons along grafts of peripheral nerve

1985 • 72 citations

Local Changes in Vascular Architecture Following Partial Spinal Cord Lesion in the Rat

1997 • 71 citations

Origin of the connective tissue scar in the transected rat spinal cord

1981 • 70 citations

Chordoid meningioma in a child

1998 • 68 citations

The Semaphorins: A Family of Axonal Guidance Molecules?

1996 • 68 citations

Inhibitory factors controlling growth cone motility and guidance

1994 • 65 citations

Neuroplasticity in the Sparing or Deterioration of Function After Early Olfactory Tract Lesions

1975 • 62 citations

Target-deprived CNS neurons express the NGF gene while reactive glia around their axonal terminals contain low and high affinity NGF receptors

1994 • 61 citations

Tenascin in the injured rat optic nerve and in non‐neuronal cells in vitro: Potential role in neural repair

1994 • 61 citations

Neurotrophic factors in regeneration

1991 • 61 citations

Axonal interactions with connective tissue and glial substrata during optic nerve regeneration in Xenopus larvae and adults

1982 • 60 citations

SPINAL CORD TRANSECTION: A QUANTITATIVE ANALYSIS OF ELEMENTS OF THE CONNECTIVE TISSUE MATRIX FORMED WITHIN THE SITE OF LESION FOLLOWING ADMINISTRATION OF PIROMEN, CYTOXAN OR TRYPSIN

1979 • 57 citations

Oligodendroglial reaction following spinal cord injury in rat: Transient upregulation of MBP mRNA

1998 • 55 citations

Isolation and characterization of a bovine neural specific protein (CRMP-2) cDNA homologous to unc-33, a C. elegans gene implicated in axonal outgrowth and guidance

1998 • 54 citations

The heterogeneity of the reticulum of rat peripheral lymphoid organs identified by monoclonal antibodies

1989 • 48 citations

Leptomeningeal cells modulate the neurite growth promoting properties of astrocytes in vitro

1997 • 46 citations

Ultrastructural study on meningeal regeneration and meningo-glial relationships after cerebral stab wound in the adult rat

1988 • 45 citations

Trigeminal Ganglion Axons Are Repelled By Their Presumptive Targets

1998 • 44 citations

Immunolocalization of B-50 (GAP-43) in the mouse olfactory bulb: Predominant presence in preterminal axons

1992 • 42 citations

Developmental factors affecting regeneration in the central nervous system: early but not late formed mitral cells reinnervate olfactory cortex after neonatal tract section

1983 • 42 citations

Topical glucocorticoids modulate the lesion interface after cerebral cortical stab wounds in adult rats

1996 • 39 citations

Nerve Growth Factor Induces Process Formation in Meningeal Cells: Implications for Scar Formation in the Injured CNS

1998 • 38 citations

Changes in astroglial scar formation in rat optic nerve as a function of development

1990 • 36 citations

RESPONSE OF FETAL AND NEONATAL RAT BRAIN TO INJURY

1987 • 36 citations

Elevated expression of B‐50 (GAP‐43)‐mRNA in a subpopulation of olfactory bulb mitral cells following axotomy

1993 • 29 citations

Identification of Meningeal Cell Released Neurite Promoting Activities for Embryonic Hippocampal Neurons

1991 • 28 citations

The pia mater — a conduit for regenerating axons after ventral root replantation

1991 • 21 citations

Rapid fiber reorganization after early olfactory tract section and bulbectomy in the hamster

1983 • 19 citations

Developmental changes in the astrocytic response to lateral olfactory tract section

1986 • 14 citations

Leptomeningeal and skin fibroblasts: Two different cell types?

1994 • 13 citations

The acute microvascular responses to spinal cord injury.

1979 • 13 citations

Neurotrophic factors and CNS regeneration

1998 • 12 citations

Collagen biosynthesis in healing wounds of the spinal cord and surrounding membranes.

1980 • 7 citations

Implantation of cultured human leptomeningeal cells into rat brain

1997 • 5 citations

Deleted Work

1955 • 0 citations

Cited By (0)

Loading...
Expression of the Gene Encoding the Chemorepellent Semaphorin III Is Induced in the… (1999) – Molecular and Cellular Neuroscience | Metascience Observatory Explorer