Two Forms of Hippocampal Long-Term Depression, the Counterpart of Long-Term Potentiation

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Long‐lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path

1973 • 7,118 citations

Magnesium gates glutamate-activated channels in mouse central neurones

1984 • 3,999 citations

Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones

1984 • 2,822 citations

NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones

1986 • 1,842 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade.

1992 • 1,675 citations

Short-Term Synaptic Plasticity

1989 • 1,464 citations

Deficient Hippocampal Long-Term Potentiation in α-Calcium-Calmodulin Kinase II Mutant Mice

1992 • 1,458 citations

Inhibition of Postsynaptic PKC or CaMKII Blocks Induction But Not Expression of LTP

1989 • 1,335 citations

Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain

1985 • 1,294 citations

A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory.

1989 • 1,114 citations

Intracellular injections of EGTA block induction of hippocampal long-term potentiation

1983 • 1,106 citations

Differential Presynaptic Localization of Metabotropic Glutamate Receptor Subtypes in the Rat Hippocampus

1997 • 1,105 citations

Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus

1992 • 1,088 citations

Involvement of a calcineurin/ inhibitor-1 phosphatase cascade in hippocampal long-term depression

1994 • 1,063 citations

An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation

1989 • 1,015 citations

NMDA-receptor-dependent synaptic plasticity: multiple forms and mechanisms

1993 • 893 citations

Contrasting properties of two forms of long-term potentiation in the hippocampus

1995 • 839 citations

Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor ε1 subunit

1995 • 832 citations

Postsynaptic Calcium Is Sufficient for Potentiation of Hippocampal Synaptic Transmission

1988 • 830 citations

Comparison of Two Forms of Long-Term Potentiation in Single Hippocampal Neurons

1990 • 755 citations

Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors

1993 • 736 citations

Developmental changes in distribution of NMDA receptor channel subunit mRNAs

1992 • 718 citations

An Essential Role for Protein Phosphatases in Hippocampal Long-Term Depression

1993 • 678 citations

Modulation of synaptic transmission and long-term potentiation: effects on paired pulse facilitation and EPSC variance in the CA1 region of the hippocampus

1993 • 675 citations

Structure and function of the NMDA receptor channel

1995 • 645 citations

Mediation of Hippocampal Mossy Fiber Long-Term Potentiation by Cyclic AMP

1994 • 600 citations

Signal transduction, pharmacological properties, and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4

1993 • 585 citations

Coexistence of peptides and classical neurotransmitters

1983 • 559 citations

Distribution of the messenger RNA for a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat

1993 • 554 citations

Two Distinct Forms of Long-Term Depression Coexist in CA1 Hippocampal Pyramidal Cells

1997 • 547 citations

Long-term potentiation of guinea pig mossy fiber responses is not blocked by N-methyl d-aspartate antagonists

1986 • 545 citations

The CaM kinase II hypothesis for the storage of synaptic memory

1994 • 510 citations

cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase

1994 • 501 citations

Impairment of Suckling Response, Trigeminal Neuronal Pattern Formation, and Hippocampal LTD in NMDA Receptor ε2 Subunit Mutant Mice

1996 • 486 citations

Postsynaptic Induction and Presynaptic Expression of Hippocampal Long-Term Depression

1994 • 481 citations

Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors

1997 • 469 citations

Calcium/calmodulin-dependent kinase II and long-term potentiation enhance synaptic transmission by the same mechanism.

1995 • 451 citations

Molecular Diversity and Functions of Glutamate Receptors

1994 • 445 citations

Phosphorylation and regulation of glutamate receptors by calcium/calmodulin-dependent protein kinase II

1993 • 437 citations

Distinct short-term plasticity at two excitatory synapses in the hippocampus

1996 • 428 citations

NMDA application potentiates synaptic transmission in the hippocampus

1988 • 421 citations

Three‐dimensional analysis of the structure and composition of CA3 branched dendritic spines and their synaptic relationships with mossy fiber boutons in the rat hippocampus

1992 • 418 citations

Peptidergic transmission in sympathetic ganglia of the frog.

1982 • 387 citations

Postsynaptic contribution to long-term potentiation revealed by the analysis of miniature synaptic currents

1992 • 372 citations

The antagonism of amino acid‐induced excitations of rat hippocampal CA1 neurones in vitro.

1983 • 360 citations

The opioid peptide dynorphin mediates heterosynaptic depression of hippocampal mossy fibre synapses and modulates long-term potentiation

1993 • 342 citations

Impairment of Hippocampal Mossy Fiber LTD in Mice Lacking mGluR2

1996 • 342 citations

Activation of metabotropic glutamate receptor type 2/3 suppresses transmission at rat hippocampal mossy fibre synapses.

1996 • 341 citations

Postsynaptic hyperpolarization during conditioning reversibly blocks induction of long-term potentiation

1986 • 324 citations

The role of Ca2+ channels in hippocampal mossy fiber synaptic transmission and long-term potentiation

1994 • 297 citations

A genetic test of the effects of mutations in PKA on mossy fiber ltp and its relation to spatial and contextual learning

1995 • 275 citations

The role of presynaptic calcium in short-term enhancement at the hippocampal mossy fiber synapse

1994 • 275 citations

Ca2+ Entry via postsynaptic voltage-sensitive Ca2+ channels can transiently potentiate excitatory synaptic transmission in the hippocampus

1992 • 237 citations

Immunohistochemical localization of metabotropic glutamate receptors, mGluR2 and mGluR3, in rat cerebellar cortex

1994 • 210 citations

Neocortical long-term potentiation

1993 • 185 citations

Presynaptic changes during mossy fibre LTP revealed by NMDA receptor-mediated synaptic responses

1995 • 179 citations

Presynaptic Long-Term Depression at the Hippocampal Mossy Fiber—CA3 Synapse

1996 • 162 citations

Induction of long-term potentiation at hippocampal mossy-fiber synapses follows a Hebbian rule

1990 • 145 citations

The role of Ca2+ entry via synaptically activated NMDA receptors in the induction of long-term potentiation

1993 • 140 citations

Differential expression of metabotropic glutamate receptors in the hippocampus and entorhinal cortex of the rat

1994 • 130 citations

Adenylate cyclases: critical foci in neuronal signaling

1995 • 125 citations

A rise in postsynaptic Ca 2+ potentiates miniature excitatory postsynaptic currents and AMPA responses in hippocampal neurons

1994 • 113 citations

Long-Term Synaptic Potentiation in the Superior Cervical Ganglion

1982 • 111 citations

2-Amino-4-phosphonobutyrate selectively blocks mossy fiber-CA3 responses in guinea pig but not rat hippocampus

1984 • 108 citations

Pharmacology of metabotropic glutamate receptors at the mossy fiber synapses of the guinea pig hippocampus

1995 • 107 citations

A LHRH-like peptidergic neurotransmitter capable of ‘action at a distance’ in autonomic ganglia

1983 • 101 citations

Identification of a Ca2+/calmodulin-dependent protein kinase II regulatory phosphorylation site in non-N-methyl-D-aspartate glutamate receptors.

1995 • 94 citations

Separate mechanisms of long-term potentiation in two input systems to CA3 pyramidal neurons of rat hippocampal slices as revealed by the whole-cell patch-clamp technique

1991 • 72 citations

Sustained rise in ACh sensitivity of a sympathetic ganglion cell induced by postsynaptic electrical activities

1983 • 45 citations

Mossy fiber long-term potentiation shows specificity but no apparent cooperativity

1992 • 41 citations

Calcium- and calmodulin-dependent phosphorylation of AMPA type glutamate receptor subunits by endogenous protein kinases in the post-synaptic density

1997 • 38 citations