Achieving Stability of Lipopolysaccharide-Induced NF-κB Activation

Initial sequencing and analysis of the human genome

2001 • 23,520 citations

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

1998 • 5,178 citations

Toll-like receptors: critical proteins linking innate and acquired immunity

2001 • 4,673 citations

Signaling to NF-κB

2004 • 3,768 citations

Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway

2003 • 3,104 citations

NF-κB functions as a tumour promoter in inflammation-associated cancer

2004 • 2,370 citations

A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

1997 • 2,137 citations

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

1997 • 2,048 citations

The IκB-NF-κB Signaling Module: Temporal Control and Selective Gene Activation

2002 • 1,805 citations

Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB

2001 • 1,427 citations

Toll-Like Receptor Signaling Pathways

2003 • 1,236 citations

Oscillations in NF-κB Signaling Control the Dynamics of Gene Expression

2004 • 1,170 citations

NF-κB Controls Expression of Inhibitor IκBα: Evidence for an Inducible Autoregulatory Pathway

1993 • 1,141 citations

A physical and functional map of the human TNF-α/NF-κB signal transduction pathway

2004 • 993 citations

IRF3 Mediates a TLR3/TLR4-Specific Antiviral Gene Program

2002 • 844 citations

RIP1 is an essential mediator of Toll-like receptor 3–induced NF-κB activation

2004 • 821 citations

Toll/IL-1 Receptor Domain-Containing Adaptor Inducing IFN-β (TRIF) Associates with TNF Receptor-Associated Factor 6 and TANK-Binding Kinase 1, and Activates Two Distinct Transcription Factors, NF-κB and IFN-Regulatory Factor-3, in the Toll-Like Receptor Signaling

2003 • 692 citations

Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha.

1993 • 639 citations

One Nucleotide in a κB Site Can Determine Cofactor Specificity for NF-κB Dimers

2004 • 383 citations

Toll-like receptor 3-mediated activation of NF-κB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-β

2004 • 365 citations

The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms.

1993 • 361 citations

Cutting Edge: TNFR-Associated Factor (TRAF) 6 Is Essential for MyD88-Dependent Pathway but Not Toll/IL-1 Receptor Domain-Containing Adaptor-Inducing IFN-β (TRIF)-Dependent Pathway in TLR Signaling

2004 • 294 citations

Investigations Into the Analysis and Modeling of the TNFα-Mediated NF-κB-Signaling Pathway

2003 • 85 citations

Identification of Mouse MD-2 Residues Important for Forming the Cell Surface TLR4-MD-2 Complex Recognized by Anti-TLR4-MD-2 Antibodies, and for Conferring LPS and Taxol Responsiveness on Mouse TLR4 by Alanine-Scanning Mutagenesis

2003 • 73 citations