Human bradykinin B2 receptors isolated by receptor-specific monoclonal antibodies are tyrosine phosphorylated.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

SH2 domains recognize specific phosphopeptide sequences

1993 • 2,685 citations

Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody.

1983 • 792 citations

Direct activation of the serine/threonine kinase activity of raf-1 through tyrosine phosphorylation by the PDGF β-receptor

1989 • 513 citations

Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor

1992 • 472 citations

Expression cloning of a rat B2 bradykinin receptor.

1991 • 430 citations

Bradykinin as a pain mediator: receptors are localized to sensory neurons, and antagonists have analgesic actions.

1988 • 396 citations

Bombesin, vasopressin, and endothelin stimulation of tyrosine phosphorylation in Swiss 3T3 cells. Identification of a novel tyrosine kinase as a major substrate.

1992 • 296 citations

Characterization of a tyrosine-specific kinase activity in human fibroblast membranes stimulated by platelet-derived growth factor.

1982 • 253 citations

Regulation of adrenergic receptor function by phosphorylation. I. Agonist-promoted desensitization and phosphorylation of alpha 1-adrenergic receptors coupled to inositol phospholipid metabolism in DDT1 MF-2 smooth muscle cells.

1987 • 206 citations

Agonist-dependent phosphorylation of the alpha 2-adrenergic receptor by the beta-adrenergic receptor kinase.

1987 • 156 citations

Activation of protein formation and cell division by bradykinin and des-Arg9-bradykinin.

1984 • 130 citations

Molecular cloning, functional expression and pharmacological characterization of a human bradykinin B2 receptor gene

1992 • 125 citations

Two bradykinin binding sites with picomolar affinities.

1986 • 123 citations

Bradykinin and bombesin rapidly stimulate tyrosine phosphorylation of a 120-kDa group of proteins in Swiss 3T3 cells.

1991 • 117 citations

The tyrosine kinase inhibitors methyl 2,5‐dihydroxycinnamate and genistein reduce thrombin‐evoked tyrosine phosphorylation and Ca²⁺ entry in human platelets

1993 • 113 citations

Introduction of Macromolecules into Bovine Adrenal Medullary Chromaffin Cells and Rat Pheochromocytoma Cells (PC12) by Permeabilization with Streptolysin O: Inhibitory Effect of Tetanus Toxin on Catecholamine Secretion

1989 • 112 citations

Isolation and identification of two hemolytic forms of streptolysin-O

1984 • 112 citations

The regulatory role of known tyrosine autophosphorylation sites of the insulin receptor kinase domain. An assessment by replacement with neutral and negatively charged amino acids.

1991 • 112 citations

Cross-talk between tyrosine kinase and G-protein-linked receptors. Phosphorylation of beta 2-adrenergic receptors in response to insulin.

1992 • 102 citations

Association of Fyn with the activated platelet-derived growth factor receptor: requirements for binding and phosphorylation.

1992 • 87 citations

Bradykinin Receptor‐Mediated Cyclic GMP Formation in a Nerve Cell Population (Murine Neuroblastoma Clone N1E‐115)

1984 • 85 citations

Multiple agonist-affinity states of opioid receptors: regulation of binding by guanyl nucleotides in guinea pig cortical, NG108-15, and 7315c cell membranes.

1988 • 78 citations

Chronic desensitization to bombesin by progressive down-regulation of bombesin receptors in Swiss 3T3 cells. Distinction from acute desensitization.

1990 • 69 citations

Structural features of the human bradykinin B2 receptor probed by agonists, antagonists, and anti-idiotypic antibodies

1993 • 67 citations

Bradykinin receptors undergo ligand-induced desensitization

1990 • 49 citations

Insulin-mimetic anti-insulin receptor monoclonal antibodies stimulate receptor kinase activity in intact cells.

1990 • 48 citations

Cloning of ligand-specific cell lines via gene transfer: identification of a D2 dopamine receptor subtype.

1989 • 41 citations

Purification and characterization of the rat liver vasopressin (V1) receptor.

1987 • 39 citations

Regulation of prostaglandin synthesis mediated by thrombin and b2 bradykinin receptors in a fibrosarcoma cell line

1982 • 35 citations

Solubilization and characterization of B2 bradykinin receptors from cultured human fibroblasts

1991 • 33 citations

Reinforcement of Signal Generation at B2 Bradykinin Receptors by Insulin, Epidermal Growth Factors, and Other Growth Factors

1989 • 31 citations

Characterization of soluble bradykinin receptor-like binding sites

1987 • 18 citations

Diversity of B2 bradykinin receptors with nanomolar affinity expressed in passaged IMR90 human lung fibroblasts.

1992 • 14 citations

Bradykinin recognizes different molecular forms of the B2 kinin receptor in the presence and absence of guanine nucleotides

1991 • 9 citations